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srebp 1c  (Proteintech)


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    Structured Review

    Proteintech srebp 1c
    Srebp 1c, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srebp+1c/SREBF1+Fusion+Protein/pmc13619958-49-8-12
    Average 95 stars, based on 24 article reviews
    srebp 1c - by Bioz Stars, 2026-10
    95/100 stars

    Images

    Related Articles

    Incubation:

    Article Title: Qingyi Decoction Alleviates Alcoholic Pancreatitis by Improving Glycerolipid Homeostasis via the AMPK/SREBP-1c/PPARα Pathway
    Article Snippet: .. Subsequently, membranes were blocked with a 5% skim milk solution for 1.5 h. Antibodies AMPKα (Rabbit, Proteintech, 1:1000), p-AMPKα (Rabbit, CST, 1:1000), SREBP-1c (Rabbit, Affinity, 1:1000), ACC1 (Rabbit, ABclonal, 1:1000), FASN (Rabbit, Proteintech, 1:5000), PPARα (Rabbit, Proteintech, 1:1000) and CPT1A (Mouse, Affinity, 1:5000) were added overnight at 4°C, and horseradish peroxidase (HRP) conjugated secondary antibodies (ABclonal, 1:10000) was incubated for 1 h at room temperature. ..

    Article Title: Nobiletin alleviates alcoholic fatty liver disease by regulating lipid metabolism and oxidative stress via Ephx1 and Sult1a1.
    Article Snippet: Background: : Alcoholic fatty liver disease (AFLD) remains a global health burden with limited treatment options.. This study investigates nobiletin (NOB), a hexamethoxyflavone, for its potential in AFLD treatment through integrated epidemiological and mechanistic approaches.. Objectives: : This study integrated population-based analysis of dietary flavone intake with experimental investigations to examine the association between flavone intake and AFLD risk and to elucidate the molecular mechanisms underlying the hepatoprotective effects of NOB in AFLD.

    Western Blot:

    Article Title: Pu-erh tea regulated chronic low-grade inflammation and multi-organ interaction dysfunction via the “gut microbiota-SCFAs-mitochondria” axis
    Article Snippet: .. The antibodies used for Western blot were: FXR (Affinity, DF12511), PPAR-α (Affinity, AF5301), NFκB (Affinity, AF5006), NLRP3(Affinity, DF7438), SREBP-1c (Affinity, AF6283), Occludin (Proteintech,66378), ZO-1 (Servicebio, GB115686), TLR9 (Affinity, DF2970), Cleaved Caspase-1 (Cell Signaling Technology, 89332), ASC (Santa Cruz Biotechnology, 22514), Heat shock protein (HSP) 60 (Affinity, AF5374), GAPDH (Servicebio, GB15004). .. Short-chain fatty acids (SCFAs) standards used in the experiment: acetic acid (A116165), propionic acid (P110445), butyric acid (B110439), isobutyric acid (I103524), valeric acid (V108272), and isovaleric acid (I108280) were purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. Serum biochemical indicators [alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), and total cholesterol (TC)] were measured using Nanjing Jiancheng commercial kits.

    other:

    Article Title: Bruceine A ameliorates hepatic steatosis and oxidative stress in alcoholic liver disease by activating Farnesoid X receptor to upregulate forkhead box A2 expression.
    Article Snippet: Background: Alcoholic liver disease (ALD) represents a major risk that threatens human health worldwide and lacks effective therapies.. Alcohol-induced inflammation and oxidative stress can trigger and aggravate liver steatosis and promote the development of diseases such as alcoholic liver fibrosis without effective treatment.. Bruceine A (BA), a compound extracted from traditional Chinese medicine Brucea javanica, exhibits various activities in multiple diseases.



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    srebp 1c  (ABclonal Biotechnology)
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    ( A–E ) The mRNA levels of <t>SREBP-1c,</t> ACC1, FASN, PPARα, and CPT1A in pancreatic tissues measured by RT-qPCR (n=3, * P <0.05, ** P <0.01, *** P <0.001, ns indicates no statistical significance).
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    protein 1c srebp 1c  (Santa Cruz Biotechnology)
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    Effects of Tofo on the hepatic protein levels. A Hepatic protein levels of ACC, FASN, <t>SREBP-1c,</t> CD36, FATP2, CPT1a, FXR, and β-actin. B The protein levels were normalized relative to the expression of β-actin. Data are presented as mean ± SD ( n = 3 per group). Statistical analyses were performed using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, and “ns” non-significant
    Protein 1c Srebp 1c, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    ( A–E ) The mRNA levels of SREBP-1c, ACC1, FASN, PPARα, and CPT1A in pancreatic tissues measured by RT-qPCR (n=3, * P <0.05, ** P <0.01, *** P <0.001, ns indicates no statistical significance).

    Journal: Journal of Inflammation Research

    Article Title: Qingyi Decoction Alleviates Alcoholic Pancreatitis by Improving Glycerolipid Homeostasis via the AMPK/SREBP-1c/PPARα Pathway

    doi: 10.2147/JIR.S537259

    Figure Lengend Snippet: ( A–E ) The mRNA levels of SREBP-1c, ACC1, FASN, PPARα, and CPT1A in pancreatic tissues measured by RT-qPCR (n=3, * P <0.05, ** P <0.01, *** P <0.001, ns indicates no statistical significance).

    Article Snippet: Subsequently, membranes were blocked with a 5% skim milk solution for 1.5 h. Antibodies AMPKα (Rabbit, Proteintech, 1:1000), p-AMPKα (Rabbit, CST, 1:1000), SREBP-1c (Rabbit, Affinity, 1:1000), ACC1 (Rabbit, ABclonal, 1:1000), FASN (Rabbit, Proteintech, 1:5000), PPARα (Rabbit, Proteintech, 1:1000) and CPT1A (Mouse, Affinity, 1:5000) were added overnight at 4°C, and horseradish peroxidase (HRP) conjugated secondary antibodies (ABclonal, 1:10000) was incubated for 1 h at room temperature.

    Techniques: Quantitative RT-PCR

    ( A–F ) The protein levels of AMPKα, p-AMPKα, SREBP-1c, ACC1, FASN, PPARα, and CPT1A in pancreatic tissues detected by Western blot (n=3, * P <0.05, ** P <0.01, *** P <0.001, ns indicates no statistical significance).

    Journal: Journal of Inflammation Research

    Article Title: Qingyi Decoction Alleviates Alcoholic Pancreatitis by Improving Glycerolipid Homeostasis via the AMPK/SREBP-1c/PPARα Pathway

    doi: 10.2147/JIR.S537259

    Figure Lengend Snippet: ( A–F ) The protein levels of AMPKα, p-AMPKα, SREBP-1c, ACC1, FASN, PPARα, and CPT1A in pancreatic tissues detected by Western blot (n=3, * P <0.05, ** P <0.01, *** P <0.001, ns indicates no statistical significance).

    Article Snippet: Subsequently, membranes were blocked with a 5% skim milk solution for 1.5 h. Antibodies AMPKα (Rabbit, Proteintech, 1:1000), p-AMPKα (Rabbit, CST, 1:1000), SREBP-1c (Rabbit, Affinity, 1:1000), ACC1 (Rabbit, ABclonal, 1:1000), FASN (Rabbit, Proteintech, 1:5000), PPARα (Rabbit, Proteintech, 1:1000) and CPT1A (Mouse, Affinity, 1:5000) were added overnight at 4°C, and horseradish peroxidase (HRP) conjugated secondary antibodies (ABclonal, 1:10000) was incubated for 1 h at room temperature.

    Techniques: Western Blot

    Effects of Tofo on the hepatic protein levels. A Hepatic protein levels of ACC, FASN, SREBP-1c, CD36, FATP2, CPT1a, FXR, and β-actin. B The protein levels were normalized relative to the expression of β-actin. Data are presented as mean ± SD ( n = 3 per group). Statistical analyses were performed using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, and “ns” non-significant

    Journal: BMC Gastroenterology

    Article Title: Tofogliflozin attenuates liver steatosis and fibrosis in non-diabetic non-alcoholic steatohepatitis mice

    doi: 10.1186/s12876-026-04610-1

    Figure Lengend Snippet: Effects of Tofo on the hepatic protein levels. A Hepatic protein levels of ACC, FASN, SREBP-1c, CD36, FATP2, CPT1a, FXR, and β-actin. B The protein levels were normalized relative to the expression of β-actin. Data are presented as mean ± SD ( n = 3 per group). Statistical analyses were performed using one-way ANOVA. * P < 0.05, ** P < 0.01, *** P < 0.001, and “ns” non-significant

    Article Snippet: The primary antibodies used in immunoblotting included antibodies against acetyl-CoA carboxylase (ACC) (#3676, Cell Signaling Technology, MA, USA), cluster of differentiation 36 (CD36) (#28109, Cell Signaling Technology), carnitine palmitoyltransferase 1a (CPT1a) (ab234111, Abcam), fatty acid synthase (FASN) (#3180, Cell Signaling Technology), fatty acid transport protein 2 (FATP2) (#78771, Cell Signaling Technology), farnesoid X receptor (FXR) (#72105, Cell Signaling Technology), and sterol regulatory element binding protein-1c (SREBP-1c) (sc-13551, Santa Cruz Biotechnology, TX, USA).

    Techniques: Expressing