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Macklin Inc span 80
Span 80, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/span+80/80+span/pmc13113478-40-19-24
Average 86 stars, based on 1 article reviews
span 80 - by Bioz Stars, 2026-10
86/100 stars

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Article Title: On-Demand Collaborative Delivery for Remodeling the Senescent Microenvironment in Intervertebral Disc Degeneration.
Article Snippet: The senescent microenvironment, defined as the cellular environment surrounding senescent cells, plays a pivotal role in tissue degenerative diseases by promoting inflammation, disrupting extracellular matrix homeostasis, and inducing senescence in neighboring healthy cells.. By analyzing the etiology of the senescent microenvironment in intervertebral disc degeneration (IVDD), senescence-associated secretory phenotype (SASP)-positive nucleus pulposus cells (NPCs) and pro-inflammatory macrophages were considered the most likely primary contributors to this pathological microenvironment.. Inspired by these findings, we developed an on-demand collaborative delivery system that concurrently suppresses the SASP in senescent NPCs and reprograms macrophages to attenuate intervertebral disc degeneration.

Article Title: Rapid self-assembly of lignin and dopamine to synthesis acid-base resistant superhydrophobic coating for oil-water separation
Article Snippet: • The lignin surface was functionalized to fabricate superhydrophobic coating.. • The coating exhibited significant superhydrophobic stability and durability.. • A superior flux of 906.35 L m 2 h 1 for oil-water mixtures separation was

Article Title: Reactive polyacrylate-modified WPUA IPN coatings covalently integrated with PP-g-NH₂ for strong adhesion to expanded polypropylene
Article Snippet: A novel waterborne polyurea (WPUA) coating system with an interpenetrating polymer network (IPN) structure was developed to overcome the adhesion limitations of coatings on expanded polypropylene (EPP) substrates.. Amino-functionalized polypropylene (PP-g-NH2) was introduced as a reactive adhesion promoter, forming covalent linkages with urethane-related groups in WPUA and enhancing interfacial affinity with the EPP surface through local chain interpenetration and van der Waals interactions.. Two polyacrylate (PA) systemsmethyl methacrylate (MMA)/butyl acrylate (BA) (IPN-M) and isobornyl acrylate (iBOA)/acrylic acid (AA) (IPN-I)-were incorporated to construct IPN structures, significantly enhancing interfacial compatibility, mechanical properties, and water resistance.

Article Title: Engineering Bone-Mimetic Microspheres to Recapitulate the Tumor Microenvironment for In Vitro Osteosarcoma Modeling
Article Snippet: GelMA, PEGDA, and lithium phenyl (2,4,6-trimethylbenzoyl) phosphinate (LAP) were bought from Engineering for Life (Suzhou, China). nHA (H875580) and Span 80 were acquired from Macklin (Shanghai, China).

Article Title: High-elongation, water-weldable, and fully degradable biomass foams fabricated via oven drying
Article Snippet: Span 80, Tween 80, xanthan gum, sodium bromide, and chloroacetic acid were obtained from Macklin Biochemical Co. Ltd. (Shanghai, China).

Dissolution:

Article Title: Multifunctional hydrogel microspheres regulate the balance of osteoblastic-osteoclastogenesis to treat osteoporotic bone defects by the NFATc1/RANKL/MAPK signaling
Article Snippet: Osteoporosis (OP) is characterized by diminished bone mass and increased skeletal fragility, representing a metabolic disorder.. Osteoporotic bone defects (OBD) pose significant treatment challenges due to the active generation of osteoclasts (OCs) and the suppression of osteogenic differentiation.. These complications impose a substantial burden on patients and the healthcare system.

CMC:

Article Title: Enhanced transdermal delivery of S-flurbiprofen-lidocaine ionic liquid-loaded emulgel for synergistic anti-inflammation and analgesia.
Article Snippet: An S-flurbiprofen (SFP)-lidocaine (LDC) ionic liquid (IL)-loaded emulgel (SFP-LDC-IL-EMG) was developed for enhanced transdermal delivery and synergistic anti-inflammation and analgesia.. SFP-LDC IL was synthesized from SFP and LDC at a molar ratio of 1:1, dissolved in isopropyl myristate (IPM, oil phase) and incorporated into water phase to create a nanoemulsion.. The nanoemulsion was then dispersed into sodium carboxymethyl cellulose (CMC-Na) gel matrix to form the final product of SFP-LDC-IL-EMG, which was characterized via rheology, morphology and stability in detail.



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FTIR Spectra of ( A ) Span 80, ( B ) Cholesterol, ( C ) Phyllanthus emblica extract, ( D ) Blank optimized formulation, and ( E ) Phyllanthus emblica loaded optimized formulation. The spectra were recorded over 4000–400 cm −1 to evaluate possible interactions between the extract and the niosomal components. The disappearance of the characteristic C–O stretching band of Phyllanthus emblica extract at 1058 cm −1 in the niosomal formulation suggests interaction with the surfactant–cholesterol bilayer and successful encapsulation.
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FTIR Spectra of ( A ) Span 80, ( B ) Cholesterol, ( C ) Phyllanthus emblica extract, ( D ) Blank optimized formulation, and ( E ) Phyllanthus emblica loaded optimized formulation. The spectra were recorded over 4000–400 cm −1 to evaluate possible interactions between the extract and the niosomal components. The disappearance of the characteristic C–O stretching band of Phyllanthus emblica extract at 1058 cm −1 in the niosomal formulation suggests interaction with the surfactant–cholesterol bilayer and successful encapsulation.
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FTIR Spectra of ( A ) Span 80, ( B ) Cholesterol, ( C ) Phyllanthus emblica extract, ( D ) Blank optimized formulation, and ( E ) Phyllanthus emblica loaded optimized formulation. The spectra were recorded over 4000–400 cm −1 to evaluate possible interactions between the extract and the niosomal components. The disappearance of the characteristic C–O stretching band of Phyllanthus emblica extract at 1058 cm −1 in the niosomal formulation suggests interaction with the surfactant–cholesterol bilayer and successful encapsulation.
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FTIR Spectra of ( A ) Span 80, ( B ) Cholesterol, ( C ) Phyllanthus emblica extract, ( D ) Blank optimized formulation, and ( E ) Phyllanthus emblica loaded optimized formulation. The spectra were recorded over 4000–400 cm −1 to evaluate possible interactions between the extract and the niosomal components. The disappearance of the characteristic C–O stretching band of Phyllanthus emblica extract at 1058 cm −1 in the niosomal formulation suggests interaction with the surfactant–cholesterol bilayer and successful encapsulation.

Journal: Pharmaceuticals

Article Title: Development of Phyllanthus emblica Extract-Loaded Niosomes for Cancer Treatment: Formulation and In Vitro Evaluation

doi: 10.3390/ph19040582

Figure Lengend Snippet: FTIR Spectra of ( A ) Span 80, ( B ) Cholesterol, ( C ) Phyllanthus emblica extract, ( D ) Blank optimized formulation, and ( E ) Phyllanthus emblica loaded optimized formulation. The spectra were recorded over 4000–400 cm −1 to evaluate possible interactions between the extract and the niosomal components. The disappearance of the characteristic C–O stretching band of Phyllanthus emblica extract at 1058 cm −1 in the niosomal formulation suggests interaction with the surfactant–cholesterol bilayer and successful encapsulation.

Article Snippet: Span 80, Tween 20, cholesterol, and Brij 35 were purchased from Alpha Chemika, Mumbai, India.

Techniques: Formulation, Encapsulation