Review



anti inositol 1 4 5 trisphosphate receptor ip3r  (Proteintech)


Bioz Verified Symbol Proteintech is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    Proteintech anti inositol 1 4 5 trisphosphate receptor ip3r
    Anti Inositol 1 4 5 Trisphosphate Receptor Ip3r, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 65 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/ITPR1-specific+Antibody/pm42810528-62-24-28
    Average 95 stars, based on 65 article reviews
    anti inositol 1 4 5 trisphosphate receptor ip3r - by Bioz Stars, 2026-10
    95/100 stars

    Images

    Related Articles

    Mutagenesis:

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051 , Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (p-p65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349-1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4 °C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 h at 37 °C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis.
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051, Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 AR TI CL E IN P RE SS ARTICLE IN PRESS dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (pp65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349- 1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4°C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 hour at 37°C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Blocking Assay:

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051 , Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (p-p65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349-1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4 °C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 h at 37 °C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis.
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051, Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 AR TI CL E IN P RE SS ARTICLE IN PRESS dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (pp65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349- 1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4°C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 hour at 37°C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Membrane:

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051 , Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (p-p65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349-1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4 °C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 h at 37 °C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Article Title: Pentraxin 3 ameliorates glucocorticoid-induced osteonecrosis of the femoral head via TLR4/NF-κB/FGF21 signaling axis.
    Article Snippet: .. The primary antibodies including beta-Actin (1:1000 dilution, M20005F, Abmart), PTX3 (1:1000, 13797-1-AP, Proteintech), Bax (1:1000, T40051, Abmart), Bcl-2 (1:500, sc-509, Santa Cruz Biotechnology), Osteocalcin (1:1000 dilution, DF12303, Affinity), ALP (1:1000 dilution, DF6225, Affinity), Collagen I (1:1000 dilution, A24112, ABclonal), Runx2 (1:1000 AR TI CL E IN P RE SS ARTICLE IN PRESS dilution, AF5186, Affinity), OPN (1:200 dilution, AF0227, Affinity), phosphorylated p65 (pp65,1:1000 dilution, AF2006, Affinity), phosphorylated IκB alpha (p-IκB, 1:1000 dilution, 82349- 1-RR, Proteintech), Toll like receptor 4 (TLR4, 1:1000 dilution, AF7017, Affinity), Mutant myeloid differentiation primary response 88 (MyD88, 1:1000 dilution, AF5195, Affinity), p65 (1:1000 dilution, AF5006, Affinity), IκB alpha (1:1000 dilution, AF5002, Affinity) and FGF21 (1:1000 dilution, TC52978S, Abmart) diluted in the blocking buffer, were applied to the membrane and allowed to incubate overnight at 4°C to detect the target proteins. .. Following incubation with the appropriate anti-rabbit or anti-mouse secondary antibodies for 1 hour at 37°C, the protein bands were visualized using the Odyssey infrared imaging system (LI-COR® Biosciences, USA) and analyzed according to the Odyssey software manual instructions. β-actin served as the internal control.

    Immunohistochemical staining:

    Article Title: Pathophysiological interaction of dextran sodium sulfate-induced colitis and diet-induced hepatic lesions in mice.
    Article Snippet: .. Immunohistochemical examination was conducted using antibodies against Toll-like receptor 4 (TLR4, 1:100; Proteintech Group, Inc., Illinois, USA) and CXCL16 (1:500; R&D Systems, Inc., Minnesota, USA). .. Histofine Simple Stain Mouse MAX-PO (R) (Nichirei Bioscience Inc., Tokyo, Japan) and Histofine MOUSESTAIN KIT (Nichirei Bioscience Inc.) were used as secondary antibodies, and the signals were visualized using 3,3ʹ-diaminobenzidine (Wako Pure Chemical Industries, Ltd., Osaka, Japan).

    Immunohistochemistry:

    Article Title: Sodium butyrate modulates ocular surface microbiome and attenuates inflammation of meibomian gland dysfunction in ApoE -/- mice.
    Article Snippet: .. Immunohistochemistry (IHC) staining was conducted to identify cells in conjunctivae and MGs positive for CD3 (ab16669, Abcam, 1:500), CD4 (ab183685, Abcam, 1:500), toll-like receptor 4 (TLR4, 19811-1-AP, Proteintech, 1:200), toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP, ab17218, Abcam, 1:200), myeloid differentiation primary response 88 (MyD88, PA5-19918, Invitrogen, 1:250), tumor necrosis factor receptor-associated factor 6 (TRAF6, ab137452, Abcam, 1:200), interleukin-1 receptor-associated kinase (IRAK1,10478-2-AP, Proteintech, 1:200), IkappaB kinase beta (IKKβ, ab124957, Abcam, 1:200), nuclear factor-kappa B (NF-κB) p65 (ab16502, Abcam, 1:200), and interferon-gamma (IFN-γ, bs-0480R, Bioss, 1:100), IL-17A antibody (26163-1-AP, Proteintech, 1:500), and inducible nitric oxide synthase (iNOS, 80517-1-RR, Proteintech, 1:200). .. Sections were then treated with a secondary goat anti-rabbit antibody (ab205718, Abcam, 1:1000) and stained with 3,3’-diaminobenzidine (DAB, ZSGB-BIO, Beijing, China).

    Article Title: Sodium butyrate modulates ocular surface microbiome and attenuates inflammation of meibomian gland dysfunction in ApoE −/− mice
    Article Snippet: .. Immunohistochemistry (IHC) staining was conducted to identify cells in conjunctivae and MGs positive for CD3 (ab16669, Abcam, 1:500), CD4 (ab183685, Abcam, 1:500), toll-like receptor 4 (TLR4, 19811-1-AP, Proteintech, 1:200), toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP, ab17218, Abcam, 1:200), myeloid differentiation primary response 88 (MyD88, PA5-19918, Invitrogen, 1:250), tumor necrosis factor receptor-associated factor 6 (TRAF6, ab137452, Abcam, 1:200), interleukin-1 receptor-associated kinase (IRAK1, 10478-2-AP, Proteintech, 1:200), IkappaB kinase beta (IKKβ, ab124957, Abcam, 1:200), nuclear factor-kappa B (NF-κB) p65 (ab16502, Abcam, 1:200), and interferon-gamma (IFN-γ, bs-0480R, Bioss, 1:100), IL-17A antibody (26163-1-AP, Proteintech, 1:500), and inducible nitric oxide synthase (iNOS, 80517-1-RR, Proteintech, 1:200). .. Sections were then treated with a secondary goat anti-rabbit antibody (ab205718, Abcam, 1:1000) and stained with 3,3′-diaminobenzidine (DAB, ZSGB-BIO, Beijing, China).

    Staining:

    Article Title: Sodium butyrate modulates ocular surface microbiome and attenuates inflammation of meibomian gland dysfunction in ApoE -/- mice.
    Article Snippet: .. Immunohistochemistry (IHC) staining was conducted to identify cells in conjunctivae and MGs positive for CD3 (ab16669, Abcam, 1:500), CD4 (ab183685, Abcam, 1:500), toll-like receptor 4 (TLR4, 19811-1-AP, Proteintech, 1:200), toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP, ab17218, Abcam, 1:200), myeloid differentiation primary response 88 (MyD88, PA5-19918, Invitrogen, 1:250), tumor necrosis factor receptor-associated factor 6 (TRAF6, ab137452, Abcam, 1:200), interleukin-1 receptor-associated kinase (IRAK1,10478-2-AP, Proteintech, 1:200), IkappaB kinase beta (IKKβ, ab124957, Abcam, 1:200), nuclear factor-kappa B (NF-κB) p65 (ab16502, Abcam, 1:200), and interferon-gamma (IFN-γ, bs-0480R, Bioss, 1:100), IL-17A antibody (26163-1-AP, Proteintech, 1:500), and inducible nitric oxide synthase (iNOS, 80517-1-RR, Proteintech, 1:200). .. Sections were then treated with a secondary goat anti-rabbit antibody (ab205718, Abcam, 1:1000) and stained with 3,3’-diaminobenzidine (DAB, ZSGB-BIO, Beijing, China).

    Article Title: Sodium butyrate modulates ocular surface microbiome and attenuates inflammation of meibomian gland dysfunction in ApoE −/− mice
    Article Snippet: .. Immunohistochemistry (IHC) staining was conducted to identify cells in conjunctivae and MGs positive for CD3 (ab16669, Abcam, 1:500), CD4 (ab183685, Abcam, 1:500), toll-like receptor 4 (TLR4, 19811-1-AP, Proteintech, 1:200), toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP, ab17218, Abcam, 1:200), myeloid differentiation primary response 88 (MyD88, PA5-19918, Invitrogen, 1:250), tumor necrosis factor receptor-associated factor 6 (TRAF6, ab137452, Abcam, 1:200), interleukin-1 receptor-associated kinase (IRAK1, 10478-2-AP, Proteintech, 1:200), IkappaB kinase beta (IKKβ, ab124957, Abcam, 1:200), nuclear factor-kappa B (NF-κB) p65 (ab16502, Abcam, 1:200), and interferon-gamma (IFN-γ, bs-0480R, Bioss, 1:100), IL-17A antibody (26163-1-AP, Proteintech, 1:500), and inducible nitric oxide synthase (iNOS, 80517-1-RR, Proteintech, 1:200). .. Sections were then treated with a secondary goat anti-rabbit antibody (ab205718, Abcam, 1:1000) and stained with 3,3′-diaminobenzidine (DAB, ZSGB-BIO, Beijing, China).

    Western Blot:

    Article Title: 6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
    Article Snippet: With lung cancer rates climbing steadily, the development of effective prevention strategies has become more crucial than ever.. Our previous research has revealed that ginger oil possesses potential lung cancer preventive activity, demonstrating inhibitory effects against tobacco carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung cancer in A/J mice.. 6-Gingerol, a bioactive compound from ginger (Zingiber officinale Rosc.), exhibits multiple pharmacological activities.



    Similar Products

    tlr4  (MedChemExpress)
    97
    MedChemExpress tlr4
    Tlr4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/Toll-Like+Receptor+4+Antibody/pm42533582-141-0-5
    Average 97 stars, based on 1 article reviews
    tlr4 - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier
    nuclear receptor coactivator 4  (ABclonal Biotechnology)
    96
    ABclonal Biotechnology nuclear receptor coactivator 4
    Nuclear Receptor Coactivator 4, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/%5BKO+Validated%5D+NCOA4+Rabbit+pAb/10__1016_slash_j__phymed__2026__158852-90-48-58
    Average 96 stars, based on 1 article reviews
    nuclear receptor coactivator 4 - by Bioz Stars, 2026-10
    96/100 stars
    		  Buy from Supplier
    anti inositol 1 4 5 trisphosphate receptor ip3r  (Proteintech)
    95
    Proteintech anti inositol 1 4 5 trisphosphate receptor ip3r
    Anti Inositol 1 4 5 Trisphosphate Receptor Ip3r, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/ITPR1-specific+Antibody/pm42810528-62-24-28
    Average 95 stars, based on 1 article reviews
    anti inositol 1 4 5 trisphosphate receptor ip3r - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    genlisa human tnfrsf4 ox40 elisa kit  (Krishgen Biosystems)
    94
    Krishgen Biosystems genlisa human tnfrsf4 ox40 elisa kit
    Genlisa Human Tnfrsf4 Ox40 Elisa Kit, supplied by Krishgen Biosystems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/Human+Tumor+Necrosis+Factor+Receptor+Superfamily+Member+4%2C+Tnfrsf4+%2F+Ox40+GENLISA+ELISA/10__26650_slash_1964715-72-22-30
    Average 94 stars, based on 1 article reviews
    genlisa human tnfrsf4 ox40 elisa kit - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    tlr4 signaling  (MedChemExpress)
    97
    MedChemExpress tlr4 signaling
    <t>TLR4</t> inhibition supports zeolite-mediated reduction of LPS-induced NF-κB activation in THP-1 Dual cells. THP-1 Dual NF-κB reporter cells were pre-treated with the small-molecule TLR4 inhibitor TAK-242 (5 µM) for 1 h prior to stimulation with lipopolysaccharide (LPS) or combined clinoptilolite zeolite and LPS treatment conditions. DMSO (0.1%) was included as a vehicle control. Data are presented as mean ± SD. Statistical significance was determined using an unpaired Student’s t-test. ns, not significant.
    Tlr4 Signaling, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/Toll-Like+Receptor+4+Antibody/pmc13468899-99-2-15
    Average 97 stars, based on 1 article reviews
    tlr4 signaling - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier
    tlr4 agonist rs09  (MedChemExpress)
    97
    MedChemExpress tlr4 agonist rs09
    OHSV2 induces NLRP3/Caspase-1/GSDMD-dependent pyroptosis in bladder cancer cells via <t>TLR4.</t> a RT-qPCR analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5) (n = 3). b Western Blot analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5). c Immunohistochemistry analysis to detect the expression of TLR4 proteins in subcutaneous xenograft tumor tissues from nude mice. d CCK-8 assay to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the viability of bladder cancer cells (n = 6). e Western Blot analysis to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the expression of TLR4, NLRP3, Caspase-1, and GSDMD. f Western blot analysis of TLR4 after TLR4 knockdown. g CCK-8 assay showing partial restoration of cell viability after TLR4 knockdown (n = 6). h Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-overexpressing cells after OHSV2 treatment. i Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-knockdown cells after OHSV2 treatment. Data are presented as mean ± SD. Statistical significance was determined by unpaired two-tailed Student's t-test (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Tlr4 Agonist Rs09, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/Toll-Like+Receptor+4+Antibody/pmc13415730-218-1-4
    Average 97 stars, based on 1 article reviews
    tlr4 agonist rs09 - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier
    anti tlr4 antibody  (MedChemExpress)
    97
    MedChemExpress anti tlr4 antibody
    OHSV2 induces NLRP3/Caspase-1/GSDMD-dependent pyroptosis in bladder cancer cells via <t>TLR4.</t> a RT-qPCR analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5) (n = 3). b Western Blot analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5). c Immunohistochemistry analysis to detect the expression of TLR4 proteins in subcutaneous xenograft tumor tissues from nude mice. d CCK-8 assay to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the viability of bladder cancer cells (n = 6). e Western Blot analysis to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the expression of TLR4, NLRP3, Caspase-1, and GSDMD. f Western blot analysis of TLR4 after TLR4 knockdown. g CCK-8 assay showing partial restoration of cell viability after TLR4 knockdown (n = 6). h Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-overexpressing cells after OHSV2 treatment. i Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-knockdown cells after OHSV2 treatment. Data are presented as mean ± SD. Statistical significance was determined by unpaired two-tailed Student's t-test (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Anti Tlr4 Antibody, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/Toll-Like+Receptor+4+Antibody/pmc13335758-216-82-61
    Average 97 stars, based on 1 article reviews
    anti tlr4 antibody - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier
    receptor 4 tlr4 ligand monophosphoryl lipid a  (InvivoGen)
    94
    InvivoGen receptor 4 tlr4 ligand monophosphoryl lipid a
    OHSV2 induces NLRP3/Caspase-1/GSDMD-dependent pyroptosis in bladder cancer cells via <t>TLR4.</t> a RT-qPCR analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5) (n = 3). b Western Blot analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5). c Immunohistochemistry analysis to detect the expression of TLR4 proteins in subcutaneous xenograft tumor tissues from nude mice. d CCK-8 assay to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the viability of bladder cancer cells (n = 6). e Western Blot analysis to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the expression of TLR4, NLRP3, Caspase-1, and GSDMD. f Western blot analysis of TLR4 after TLR4 knockdown. g CCK-8 assay showing partial restoration of cell viability after TLR4 knockdown (n = 6). h Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-overexpressing cells after OHSV2 treatment. i Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-knockdown cells after OHSV2 treatment. Data are presented as mean ± SD. Statistical significance was determined by unpaired two-tailed Student's t-test (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Receptor 4 Tlr4 Ligand Monophosphoryl Lipid A, supplied by InvivoGen, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/receptor+4/MPLA-SM*+VacciGrade/10__1097_slash_tp__0000000000005787-76-13-23
    Average 94 stars, based on 1 article reviews
    receptor 4 tlr4 ligand monophosphoryl lipid a - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    TLR4 inhibition supports zeolite-mediated reduction of LPS-induced NF-κB activation in THP-1 Dual cells. THP-1 Dual NF-κB reporter cells were pre-treated with the small-molecule TLR4 inhibitor TAK-242 (5 µM) for 1 h prior to stimulation with lipopolysaccharide (LPS) or combined clinoptilolite zeolite and LPS treatment conditions. DMSO (0.1%) was included as a vehicle control. Data are presented as mean ± SD. Statistical significance was determined using an unpaired Student’s t-test. ns, not significant.

    Journal: Frontiers in Immunology

    Article Title: Adsorption-mediated modulation of lipopolysaccharide bioactivity by clinoptilolite zeolite with in vitro immunomodulatory effects and in vivo safety evaluation

    doi: 10.3389/fimmu.2026.1818740

    Figure Lengend Snippet: TLR4 inhibition supports zeolite-mediated reduction of LPS-induced NF-κB activation in THP-1 Dual cells. THP-1 Dual NF-κB reporter cells were pre-treated with the small-molecule TLR4 inhibitor TAK-242 (5 µM) for 1 h prior to stimulation with lipopolysaccharide (LPS) or combined clinoptilolite zeolite and LPS treatment conditions. DMSO (0.1%) was included as a vehicle control. Data are presented as mean ± SD. Statistical significance was determined using an unpaired Student’s t-test. ns, not significant.

    Article Snippet: To inhibit TLR4 signaling, cells were pre-treated with the small-molecule TLR4 inhibitor TAK-242 ( ) (MedChemExpress, HY-11109) at a final concentration of 5 μM for 1 h prior to stimulation.

    Techniques: Inhibition, Activation Assay, Control

    OHSV2 induces NLRP3/Caspase-1/GSDMD-dependent pyroptosis in bladder cancer cells via TLR4. a RT-qPCR analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5) (n = 3). b Western Blot analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5). c Immunohistochemistry analysis to detect the expression of TLR4 proteins in subcutaneous xenograft tumor tissues from nude mice. d CCK-8 assay to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the viability of bladder cancer cells (n = 6). e Western Blot analysis to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the expression of TLR4, NLRP3, Caspase-1, and GSDMD. f Western blot analysis of TLR4 after TLR4 knockdown. g CCK-8 assay showing partial restoration of cell viability after TLR4 knockdown (n = 6). h Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-overexpressing cells after OHSV2 treatment. i Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-knockdown cells after OHSV2 treatment. Data are presented as mean ± SD. Statistical significance was determined by unpaired two-tailed Student's t-test (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Journal: Molecular Biomedicine

    Article Title: Oncolytic virus OHSV2 induces pyroptosis in bladder cancer cells via the TLR4/NLRP3/Caspase-1/GSDMD pathway

    doi: 10.1186/s43556-026-00506-4

    Figure Lengend Snippet: OHSV2 induces NLRP3/Caspase-1/GSDMD-dependent pyroptosis in bladder cancer cells via TLR4. a RT-qPCR analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5) (n = 3). b Western Blot analysis of the expression levels of TLR4 in bladder cancer cells treated with different concentrations (5% PBS, MOI = 1, MOI = 5). c Immunohistochemistry analysis to detect the expression of TLR4 proteins in subcutaneous xenograft tumor tissues from nude mice. d CCK-8 assay to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the viability of bladder cancer cells (n = 6). e Western Blot analysis to evaluate the effects of OHSV2 in combination with an TLR4 inhibitor (Resatorvid) on the expression of TLR4, NLRP3, Caspase-1, and GSDMD. f Western blot analysis of TLR4 after TLR4 knockdown. g CCK-8 assay showing partial restoration of cell viability after TLR4 knockdown (n = 6). h Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-overexpressing cells after OHSV2 treatment. i Western blot analysis of NLRP3, Cleaved Caspase-1, and N-GSDMD expression in TLR4-knockdown cells after OHSV2 treatment. Data are presented as mean ± SD. Statistical significance was determined by unpaired two-tailed Student's t-test (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Article Snippet: The TLR4 agonist RS09 (MCE, USA) was administered intraperitoneally at a dose of 2 mg/kg per injection every day from day 0.

    Techniques: Quantitative RT-PCR, Expressing, Western Blot, Immunohistochemistry, CCK-8 Assay, Knockdown, Two Tailed Test