promass software (Novatia LLC)
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Promass Software, supplied by Novatia LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/promass+software/promass+software/us12173368-713-12-14
Average 90 stars, based on 1 article reviews
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other:Article Title: Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in bacterial and mammalian cells Article Snippet: The spectra was analyzed Article Title: Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells. Article Snippet: The spectra were analyzed Software:Article Title: Isolation and Partial Characterization of Novel, Structurally Uniform (Hfq 6 ) n≥8 Assemblies Carrying Accessory Transcription and Translation Factors. Article Snippet: In growing E. coli cells, the transcription−translation complexes (TTCs) form characteristic foci; however, the exact molecular composition of these superstructures is not known with certainty.. Herein, we report that, during our recently developed “fast” procedures for purification of E. coli RNA polymerase (RP), a fraction of the RP’s α/RpoA subunits is displaced from the core RP complexes and copurifies with multiprotein superstructures carrying the nucleic acid-binding protein Hfq and the ribosomal protein S6.. We show that the main components of these large multiprotein assemblies are fixed protein copy-number (Hfq6)n≥8 complexes; these complexes have a high level of structural uniformity and are distinctly unlike the previously described (Hfq6)n “head-to-tail” polymers. Article Title: Sequencing of Phosphoramidate Oligonucleotides by Acid Hydrolysis and Mass Spectrometry. Article Snippet: Hydrolysis of N3’-P5’ phosphoramidate and thiophosphoramidate oligonucleotides with 0.1% formic acid leads to the cleavage of the 3’ N-P bond and generates two products one of which contains a 5’-phosphate.. Analysis of the hydrolytic products by liquid chromatography coupled to mass spectrometry reveals the mass ladder from both termini, which is used to determine the sequence.. While acid hydrolysis does not result in depurination, internal fragments especially in the low mass range are detected. Article Title: Compositions and analysis of dephosphorylated oligoribonucleotides Article Snippet: .. Oligonucleotide mass fingerprinting was performed by deconvoluting raw intact MS data with Article Title: Reductive Desulfuration as an Important Tool in Detection of Small Molecule Modifications to Payload of Antibody Drug Conjugates. Article Snippet: A high resolution accurate mass LC−MS method was developed to facilitate the characterization of a subset of antibody drug conjugate (ADC) biotherapeutics, where the payload is linked to the antibody by a thioether bond.. Desulfuration of the thioether linker was optimized for release of the payload to take advantage of the high resolution and high mass accuracy of the Orbitrap to characterize metabolism of the payload.. Two model ADCs, trastuzumab emtansine (T-DM1) and SigmaMAb dansyl-cadavarine-SMCC (SigmaMAb ADC mimic) were selected for optimization of the desulfuration reaction as a function of reaction time, pH, organic solvent, and chaotropic reagents (urea, guanidine HCl) by monitoring the yield of released desulfurated DM1 from T-DM1 and desulfurated dansyl-cadaverine-SMCC from SigmaMAb ADC mimic, respectively. Article Title: Methods and compositions for modifying a single stranded target nucleic acid Article Snippet: .. Mass spectral deconvolution was performed using |
