Review



mouse anti pp53 s392  (Cell Signaling Technology Inc)


Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93

    Structured Review

    Cell Signaling Technology Inc mouse anti pp53 s392
    Mouse Anti Pp53 S392, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 176 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser392)+Antibody/pm41813667-172-17-21
    Average 93 stars, based on 176 article reviews
    mouse anti pp53 s392 - by Bioz Stars, 2026-09
    93/100 stars

    Images

    Related Articles

    SDS Page:

    Article Title: Phototoxicity-free blue light for enhancing therapeutic angiogenic efficacy of stem cells.
    Article Snippet: diode (bOLED) as a safe and effective light source that could generate a low amount of heat and luminance compared to conventional light sources (e.g., light-emitting diodes).. We compared phototoxicity of bOLED light with different light fluences to human adipose-derived stem cells (hADSC).. We further explored molecular mechanisms involved in the therapeutic efficacy of bOLED for enhancing angiogenic properties of hADSC, including intracellular ROS control in hADSCs.

    Membrane:

    Article Title: Chronic kidney disease amplifies severe kidney injury and mortality in a mouse model of skin arsenical exposure
    Article Snippet: .. The membrane was probed with various primary antibodies fibronectin 1:5000 (F3648, Sigma Aldrich), α-SMA 1:5000 (A5228, Sigma Aldrich), Galectin-3 1:1000 (sc-32790, Santa Cruz Biotechnology), NGAL 1:2000 (AF1857, R&D System), KIM-1 1:800 (AF1817, R&D System), p-H2AX 1:1000 (ab26350, Abcam), pATM 1:500 (AF1655, R&D System), pCHK1 1:500 (2348, CST), pP53 1:800 (9284, CST), Bax 1:1000 (2772, CST), Bcl 2 1:1000 (3498, CST), Cleaved caspase 3 1:1000 (NB100–56708, Novus Biologicals), overnight at 4°C and then washed three times with TBST. .. Finally, the membranes were incubated with HRP-conjugated secondary antibodies (Invitrogen, MA) for 1.5–2hr.

    Article Title: Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism
    Article Snippet: .. Proteins were then transferred to a polyvinylidene difluoride membrane (PVDF, Merck-Millipore, Milan, Italy) and membranes were blocked at RT with TBST (10 mM Tris-HCl pH 7.5, 100 mM NaCl, 0.1% Tween 20) containing 5% milk for 1 h. Thereafter, they were incubated on a shaker overnight at 4 °C, with a 5% BSA solution containing the primary antibody against AMPK (#2532, 1:1000), Bcl-2 (#15071, 1:1000), GAPDH (#2118, 1:1000), LDHA (#3582, 1:2000), pACC (Ser79) (#11818, 1:1000), pAKT (Thr308) (#13038, 1:1000), pAMPK (Thr 172) (#2531, 1:1000), pERK (#9101, 1:1000), pP53 (#9286, 1:1000), pP65-NF-κB (Ser 536) (#3033, 1:1000), pRb (#8516, 1:2000), Rb (#9309, 1:2000), pSTAT3 (#9145, 1:2000) (Cell Signaling Technology, Danvers, MA, USA); AKT (GTX121937, 1:4000), ATP5B (GTX132925, 1:3000), CDK4 (GTX102993, 1:3000), COX4 (GTX114330, 1:3000), CREB (GTX112846, 1:3000), Cyclin A2 (GTX103042, 1:3000), Cyclin D1 (GTX108624, 1:10000), ERK1/2 (GTX134462, 1:10000), FRA1 (GTX134242, 1:4000), HIF1α (GTX127309, 1:3000), LC3B (GTX127375, 1:2000), P21/Waf1 (GTX629543, 1:3000), p4EBP1 (GTX133181, 1:6000), 4EBP1 (GTX116315, 1: 4000), P65-NF-κB (GTX102090, 1:3000), PARP1 (GTX628836, 1:3000), pcJun (GTX133873, 1:3000), pCREB (GTX130379, 1:3000), PGM2 (GTX119168, 1:3000), pPKM2 (GTX133886, 1:3000), STAT3 (GTX104616, 1:3000), TRPC6 (GTX113859, 1:3000), UQCRC1 (GTX630393, 1:1000) (Genetex, Alton Parkway, Irvine, CA, USA); GPX4 (67763-1, 1:3000) (Proteintech, Manchester, UK); P53 (sc-263, 1:3000) (Santa Cruz Biotechnology, Dallas, TX, USA); PGC1α (PA5-38022, 1:1000) (Invitrogen, Thermo Scientific, Waltham, MA, USA); and Bcl-xL (ab77571, 1:1000) (Abcam, Cambridge, UK). .. Then, membranes were washed 3 times with TBST buffer for 30 min and incubated for 1 h with a horseradish peroxidase-conjugated secondary antibody (anti-rabbit or anti-mouse, 1:6000-1:4000, Cell Signaling Technology, Danvers, MA, USA).

    other:

    Article Title: Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study
    Article Snippet: The following antibodies were used: proliferating cell nuclear antigen (PCNA; Cat# sc-25280, RRID: AB_628109; Santa Cruz Biotechnology, Santa Cruz, CA, USA), TYR (Cat# sc-15341, RRID: AB_2256771; Santa Cruz Biotechnology), glyceraldehyde-3-phosphate dehydrogenase (Cat# sc-166545, RRID: AB_2107299; Santa Cruz Biotechnology), pp53 (Cat# 9284, RRID: AB_331464; Cell Signaling Technology, Danvers, MA, USA), p53 (Cat# sc-126, RRID: AB_628082; Santa Cruz Biotechnology), pp38 (Cat# 9211, RRID: AB_331641; Cell Signaling Technology), pCREB (Cat# 9191, RRID: AB_331606; Cell Signaling Technology), MITF (Cat# ab140606; Abcam, Cambridge, UK), anti-mouse immunoglobulin G (IgG; Cat# ADI-SAB-100-J, RRID: AB_11179634; Enzo Life Sciences, Farmingdale, NY, USA), and anti-rabbit IgG (Cat# ADI-SAB-300-J, RRID: AB_11179983; Enzo Life Sciences).

    Article Title: Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study.
    Article Snippet: The following antibodies were used: proliferating cell nuclear antigen (PCNA; Cat# sc-25280, RRID: AB_628109; Santa Cruz Biotechnology, Santa Cruz, CA, USA), TYR (Cat# sc-15341, RRID: AB_2256771; Santa Cruz Biotechnology), glyceraldehyde-3-phosphate dehydrogenase (Cat# sc-166545, RRID: AB_2107299; Santa Cruz Biotechnology), pp53 (Cat# 9284, RRID: AB_331464; Cell Signaling Technology, Danvers, MA, USA), p53 (Cat# sc-126, RRID: AB_628082; Santa Cruz Biotechnology), pp38 (Cat# 9211, RRID: AB_331641; Cell Signaling Technology), pCREB (Cat# 9191, RRID: AB_331606; Cell Signaling Technology), MITF (Cat# ab140606; Abcam, Cambridge, UK), anti-mouse immunoglobulin G (IgG; Cat# ADI-SAB-100-J, RRID: AB_11179634; Enzo Life Sciences, Farmingdale, NY, USA), and anti-rabbit IgG (Cat# ADI-SAB-300-J, RRID: AB_11179983; Enzo Life Sciences).

    Incubation:

    Article Title: Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism
    Article Snippet: .. Proteins were then transferred to a polyvinylidene difluoride membrane (PVDF, Merck-Millipore, Milan, Italy) and membranes were blocked at RT with TBST (10 mM Tris-HCl pH 7.5, 100 mM NaCl, 0.1% Tween 20) containing 5% milk for 1 h. Thereafter, they were incubated on a shaker overnight at 4 °C, with a 5% BSA solution containing the primary antibody against AMPK (#2532, 1:1000), Bcl-2 (#15071, 1:1000), GAPDH (#2118, 1:1000), LDHA (#3582, 1:2000), pACC (Ser79) (#11818, 1:1000), pAKT (Thr308) (#13038, 1:1000), pAMPK (Thr 172) (#2531, 1:1000), pERK (#9101, 1:1000), pP53 (#9286, 1:1000), pP65-NF-κB (Ser 536) (#3033, 1:1000), pRb (#8516, 1:2000), Rb (#9309, 1:2000), pSTAT3 (#9145, 1:2000) (Cell Signaling Technology, Danvers, MA, USA); AKT (GTX121937, 1:4000), ATP5B (GTX132925, 1:3000), CDK4 (GTX102993, 1:3000), COX4 (GTX114330, 1:3000), CREB (GTX112846, 1:3000), Cyclin A2 (GTX103042, 1:3000), Cyclin D1 (GTX108624, 1:10000), ERK1/2 (GTX134462, 1:10000), FRA1 (GTX134242, 1:4000), HIF1α (GTX127309, 1:3000), LC3B (GTX127375, 1:2000), P21/Waf1 (GTX629543, 1:3000), p4EBP1 (GTX133181, 1:6000), 4EBP1 (GTX116315, 1: 4000), P65-NF-κB (GTX102090, 1:3000), PARP1 (GTX628836, 1:3000), pcJun (GTX133873, 1:3000), pCREB (GTX130379, 1:3000), PGM2 (GTX119168, 1:3000), pPKM2 (GTX133886, 1:3000), STAT3 (GTX104616, 1:3000), TRPC6 (GTX113859, 1:3000), UQCRC1 (GTX630393, 1:1000) (Genetex, Alton Parkway, Irvine, CA, USA); GPX4 (67763-1, 1:3000) (Proteintech, Manchester, UK); P53 (sc-263, 1:3000) (Santa Cruz Biotechnology, Dallas, TX, USA); PGC1α (PA5-38022, 1:1000) (Invitrogen, Thermo Scientific, Waltham, MA, USA); and Bcl-xL (ab77571, 1:1000) (Abcam, Cambridge, UK). .. Then, membranes were washed 3 times with TBST buffer for 30 min and incubated for 1 h with a horseradish peroxidase-conjugated secondary antibody (anti-rabbit or anti-mouse, 1:6000-1:4000, Cell Signaling Technology, Danvers, MA, USA).

    Western Blot:

    Article Title: NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression
    Article Snippet: .. Immunoblotting, Immunohistochemistry and Immunofluorescence Hematoxylin eosin staining, IHC and western blot analysis were performed using standard protocol as described previously 4, using antibodies against HA-tag (#3724; Cell Signaling), NFATc1 (7A6, #sc7294; Santa Cruz Biotechnologies and ab25916; abcam), CD45 (#550539; BD Pharmingen), eif2α (#9722; Cell signaling), p-Eif2α (#9721; Cell Signaling), CHOP(#2895; Cell Signaling), Ddit3 (ab179823; abcam), cleaved caspase-3 (#9661; Cell signaling), cleaved caspase-1 (#67314; Cell signaling), cleaved IL-1β (#52718; Cell signaling), pP53-(s15) (#9284; Cell signaling), NLRP3 (AG-203-0014-C101; Adipogene) and β-actin (A3845; Sigma), Gasdermin D (#39754; Cell signaling), cleaved Gasdermin D (#10137; Cell signaling); TRB3 (#LS-B12111; LSBio), ATF4 (#NB100-852; Novusbio), PERK (#3192; Cell signaling), p-PERK (#3179; Cell signaling), p-PKR (#MBS856680; MyBioSource), PKR (#MBS150276; MyBioSource). ..

    Immunohistochemistry:

    Article Title: NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression
    Article Snippet: .. Immunoblotting, Immunohistochemistry and Immunofluorescence Hematoxylin eosin staining, IHC and western blot analysis were performed using standard protocol as described previously 4, using antibodies against HA-tag (#3724; Cell Signaling), NFATc1 (7A6, #sc7294; Santa Cruz Biotechnologies and ab25916; abcam), CD45 (#550539; BD Pharmingen), eif2α (#9722; Cell signaling), p-Eif2α (#9721; Cell Signaling), CHOP(#2895; Cell Signaling), Ddit3 (ab179823; abcam), cleaved caspase-3 (#9661; Cell signaling), cleaved caspase-1 (#67314; Cell signaling), cleaved IL-1β (#52718; Cell signaling), pP53-(s15) (#9284; Cell signaling), NLRP3 (AG-203-0014-C101; Adipogene) and β-actin (A3845; Sigma), Gasdermin D (#39754; Cell signaling), cleaved Gasdermin D (#10137; Cell signaling); TRB3 (#LS-B12111; LSBio), ATF4 (#NB100-852; Novusbio), PERK (#3192; Cell signaling), p-PERK (#3179; Cell signaling), p-PKR (#MBS856680; MyBioSource), PKR (#MBS150276; MyBioSource). ..

    Immunofluorescence:

    Article Title: NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression
    Article Snippet: .. Immunoblotting, Immunohistochemistry and Immunofluorescence Hematoxylin eosin staining, IHC and western blot analysis were performed using standard protocol as described previously 4, using antibodies against HA-tag (#3724; Cell Signaling), NFATc1 (7A6, #sc7294; Santa Cruz Biotechnologies and ab25916; abcam), CD45 (#550539; BD Pharmingen), eif2α (#9722; Cell signaling), p-Eif2α (#9721; Cell Signaling), CHOP(#2895; Cell Signaling), Ddit3 (ab179823; abcam), cleaved caspase-3 (#9661; Cell signaling), cleaved caspase-1 (#67314; Cell signaling), cleaved IL-1β (#52718; Cell signaling), pP53-(s15) (#9284; Cell signaling), NLRP3 (AG-203-0014-C101; Adipogene) and β-actin (A3845; Sigma), Gasdermin D (#39754; Cell signaling), cleaved Gasdermin D (#10137; Cell signaling); TRB3 (#LS-B12111; LSBio), ATF4 (#NB100-852; Novusbio), PERK (#3192; Cell signaling), p-PERK (#3179; Cell signaling), p-PKR (#MBS856680; MyBioSource), PKR (#MBS150276; MyBioSource). ..

    Staining:

    Article Title: NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression
    Article Snippet: .. Immunoblotting, Immunohistochemistry and Immunofluorescence Hematoxylin eosin staining, IHC and western blot analysis were performed using standard protocol as described previously 4, using antibodies against HA-tag (#3724; Cell Signaling), NFATc1 (7A6, #sc7294; Santa Cruz Biotechnologies and ab25916; abcam), CD45 (#550539; BD Pharmingen), eif2α (#9722; Cell signaling), p-Eif2α (#9721; Cell Signaling), CHOP(#2895; Cell Signaling), Ddit3 (ab179823; abcam), cleaved caspase-3 (#9661; Cell signaling), cleaved caspase-1 (#67314; Cell signaling), cleaved IL-1β (#52718; Cell signaling), pP53-(s15) (#9284; Cell signaling), NLRP3 (AG-203-0014-C101; Adipogene) and β-actin (A3845; Sigma), Gasdermin D (#39754; Cell signaling), cleaved Gasdermin D (#10137; Cell signaling); TRB3 (#LS-B12111; LSBio), ATF4 (#NB100-852; Novusbio), PERK (#3192; Cell signaling), p-PERK (#3179; Cell signaling), p-PKR (#MBS856680; MyBioSource), PKR (#MBS150276; MyBioSource). ..



    Similar Products

    93
    Cell Signaling Technology Inc mouse anti pp53 s392
    Mouse Anti Pp53 S392, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser392)+Antibody/pm41813667-172-17-21
    Average 93 stars, based on 1 article reviews
    mouse anti pp53 s392 - by Bioz Stars, 2026-09
    93/100 stars
      Buy from Supplier

    96
    Cell Signaling Technology Inc mouse anti pp53 s15
    Mouse Anti Pp53 S15, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser15)+Antibody/pmc13039127-214-11-15
    Average 96 stars, based on 1 article reviews
    mouse anti pp53 s15 - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    96
    Cell Signaling Technology Inc pp53 s15
    Pp53 S15, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser15)+Mouse+mAb/pmc12682131-10-0-5
    Average 96 stars, based on 1 article reviews
    pp53 s15 - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    96
    Cell Signaling Technology Inc pp53
    Pp53, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser15)+Antibody/pm41189087-45-38-43
    Average 96 stars, based on 1 article reviews
    pp53 - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    96
    Cell Signaling Technology Inc anti pp53 ser15
    Anti Pp53 Ser15, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser15)+Mouse+mAb/pmc12559235-415-21-23
    Average 96 stars, based on 1 article reviews
    anti pp53 ser15 - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    93
    Cell Signaling Technology Inc pp53 phospho p53
    Mechanisms of PD-L1 regulation in lung cancer. PD-L1 expression in tumor cells is regulated at multiple levels. The <t>p53–p21</t> axis can negatively influence PD-L1 transcription, while oncogenic pathways such as PI3K/AKT and JAK/STAT promote its up-regulation. Epigenetic mechanisms play a critical role: histone acetylation and methylation dynamically regulate chromatin accessibility, and DNA methylation (e.g., via DNMT1) can repress or activate PD-L1 transcription depending on context. Collectively, these mechanisms contribute to PD-L1-mediated immune evasion and tumor survival.
    Pp53 Phospho P53, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser15)+Rabbit+mAb/pmc12428147-3-0-3
    Average 93 stars, based on 1 article reviews
    pp53 phospho p53 - by Bioz Stars, 2026-09
    93/100 stars
      Buy from Supplier

    97
    Cell Signaling Technology Inc pp53 ser15 cell signaling
    Mechanisms of PD-L1 regulation in lung cancer. PD-L1 expression in tumor cells is regulated at multiple levels. The <t>p53–p21</t> axis can negatively influence PD-L1 transcription, while oncogenic pathways such as PI3K/AKT and JAK/STAT promote its up-regulation. Epigenetic mechanisms play a critical role: histone acetylation and methylation dynamically regulate chromatin accessibility, and DNA methylation (e.g., via DNMT1) can repress or activate PD-L1 transcription depending on context. Collectively, these mechanisms contribute to PD-L1-mediated immune evasion and tumor survival.
    Pp53 Ser15 Cell Signaling, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p38+MAPK+(Thr180%2FTyr182)+Antibody/pmc10104783__41556_2023_1096_MOESM1_ESM-38-218-220
    Average 97 stars, based on 1 article reviews
    pp53 ser15 cell signaling - by Bioz Stars, 2026-09
    97/100 stars
      Buy from Supplier

    95
    Cell Signaling Technology Inc rabbit anti pp53
    Mechanisms of PD-L1 regulation in lung cancer. PD-L1 expression in tumor cells is regulated at multiple levels. The <t>p53–p21</t> axis can negatively influence PD-L1 transcription, while oncogenic pathways such as PI3K/AKT and JAK/STAT promote its up-regulation. Epigenetic mechanisms play a critical role: histone acetylation and methylation dynamically regulate chromatin accessibility, and DNA methylation (e.g., via DNMT1) can repress or activate PD-L1 transcription depending on context. Collectively, these mechanisms contribute to PD-L1-mediated immune evasion and tumor survival.
    Rabbit Anti Pp53, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pp53/Phospho-p53+(Ser46)+Antibody/pm40588650-359-77-79
    Average 95 stars, based on 1 article reviews
    rabbit anti pp53 - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    Image Search Results


    Mechanisms of PD-L1 regulation in lung cancer. PD-L1 expression in tumor cells is regulated at multiple levels. The p53–p21 axis can negatively influence PD-L1 transcription, while oncogenic pathways such as PI3K/AKT and JAK/STAT promote its up-regulation. Epigenetic mechanisms play a critical role: histone acetylation and methylation dynamically regulate chromatin accessibility, and DNA methylation (e.g., via DNMT1) can repress or activate PD-L1 transcription depending on context. Collectively, these mechanisms contribute to PD-L1-mediated immune evasion and tumor survival.

    Journal: Cancers

    Article Title: Regulation of PD-L1 Expression by SAHA-Mediated Histone Deacetylase Inhibition in Lung Cancer Cells

    doi: 10.3390/cancers17172919

    Figure Lengend Snippet: Mechanisms of PD-L1 regulation in lung cancer. PD-L1 expression in tumor cells is regulated at multiple levels. The p53–p21 axis can negatively influence PD-L1 transcription, while oncogenic pathways such as PI3K/AKT and JAK/STAT promote its up-regulation. Epigenetic mechanisms play a critical role: histone acetylation and methylation dynamically regulate chromatin accessibility, and DNA methylation (e.g., via DNMT1) can repress or activate PD-L1 transcription depending on context. Collectively, these mechanisms contribute to PD-L1-mediated immune evasion and tumor survival.

    Article Snippet: pp53 (Phospho-p53) , CST , 12571 , 1:1000.

    Techniques: Expressing, Methylation, DNA Methylation Assay