Journal: International Journal of Nanomedicine
Article Title: Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system
doi: 10.2147/IJN.S28761
Figure Lengend Snippet: In vitro indirubin concentration-time profiles from the SMEDDS formulations and S-SMEDDS with hydrophilic polymers of ( A ) PEG 4000, ( B ) HPMC, and ( C ) PVP K17 (n = 5). Abbreviations: SMEDDS, self-microemulsifying drug delivery system; S-SMEDDS, supersaturatable self-microemulsifying drug delivery system; PEG, polyethylene glycol; PVP, polyvinylpyrrolidone; HPMC, hydroxypropyl methylcellulose.
Article Snippet: Polyoxyl 40 hydrogenated castor oil (Cremophor ® RH 40), polyoxyl castor oil (Cremophor EL), and povidone K17 (PVP K17) were from BASF, Ludwigshafen, Germany.
Techniques: In Vitro, Concentration Assay