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Panel (A) –comparison of phospholipid concentration in dodecane on naproxen apparent permeability across 0.45 µm PVDF membrane filter (LiDo 5: n = 5, LiDo 10: n = 7). Panel (B) –comparison of membrane filter material, <t>containing</t> <t>5%</t> <t>L-α-phosphatidylcholine</t> in dodecane on naproxen apparent permeability (PVDF: n = 5, PC: n = 3). PVDF – 0.45 µm pore size hydrophobic polyvinylidene fluoride membrane, PC – 0.20 µm pore size polycarbonate track etched membrane.
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Panel (A) –comparison of phospholipid concentration in dodecane on naproxen apparent permeability across 0.45 µm PVDF membrane filter (LiDo 5: n = 5, LiDo 10: n = 7). Panel (B) –comparison of membrane filter material, <t>containing</t> <t>5%</t> <t>L-α-phosphatidylcholine</t> in dodecane on naproxen apparent permeability (PVDF: n = 5, PC: n = 3). PVDF – 0.45 µm pore size hydrophobic polyvinylidene fluoride membrane, PC – 0.20 µm pore size polycarbonate track etched membrane.
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Panel (A) –comparison of phospholipid concentration in dodecane on naproxen apparent permeability across 0.45 µm PVDF membrane filter (LiDo 5: n = 5, LiDo 10: n = 7). Panel (B) –comparison of membrane filter material, containing 5% L-α-phosphatidylcholine in dodecane on naproxen apparent permeability (PVDF: n = 5, PC: n = 3). PVDF – 0.45 µm pore size hydrophobic polyvinylidene fluoride membrane, PC – 0.20 µm pore size polycarbonate track etched membrane.

Journal: Journal of Pharmacy & Pharmaceutical Sciences

Article Title: Dissolution-permeation approach for biopharmaceutical evaluation: a feasibility study using naproxen

doi: 10.3389/jpps.2026.16570

Figure Lengend Snippet: Panel (A) –comparison of phospholipid concentration in dodecane on naproxen apparent permeability across 0.45 µm PVDF membrane filter (LiDo 5: n = 5, LiDo 10: n = 7). Panel (B) –comparison of membrane filter material, containing 5% L-α-phosphatidylcholine in dodecane on naproxen apparent permeability (PVDF: n = 5, PC: n = 3). PVDF – 0.45 µm pore size hydrophobic polyvinylidene fluoride membrane, PC – 0.20 µm pore size polycarbonate track etched membrane.

Article Snippet: Soy L-α-phosphatidylcholine (95%) was obtained from Avanti Polar Lipids, USA.

Techniques: Comparison, Concentration Assay, Permeability, Membrane, Pore Size