p38 mapk activator (MedChemExpress)

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MedChemExpress p38 mapk activator
P38 Mapk Activator, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 162 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/p38+mapk+activity/Phospho-p38+alpha%2FMAPK14+(Thr180%2BTyr182)+Antibody/pm42281258-62-11-14
Average 97 stars, based on 162 article reviews

p38 mapk activator - by Bioz Stars, 2026-10

97/100 stars

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Article Title: Rack1‐mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights
Article Snippet: .. To induce ferroptosis, cells were treated with 10 μM Erastin (APExBIO Technology, Houston, TX, USA) for 24 h. Ferrostatin‐1 (Fer‐1; APExBIO Technology) was used at a concentration of 100 nM to inhibit ferroptosis for 24 h. Suppression of P38‐MAPK activity was achieved by treating cells with 520 nM doramapimod (MedChemExpress, MCE, Rahway, NJ, USA) for 24 h. To induce Nqo1 activity, cells were treated with 2‐HBA (MCE) at a concentration of 0.6 μM for 24 h. The siRNA of Rack1 (RiboBio, Guangzhou, China) was used at a concentration of 80 nM, with a treatment time of 24–36 h. .. Intracellular ferrous iron was detected using the FerroOrange fluorescent probe (Dojindo, Beijing, China).

Article Title: Rack1-mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights.
Article Snippet: .. To induce ferroptosis, cells were treated with 10 μM Erastin (APExBIO Technology, Houston, TX, USA) for 24 h. Ferrostatin-1 (Fer-1; APExBIO Technology) was used at a concentration of 100 nM to inhibit ferroptosis for 24 h. Suppression of P38-MAPK activity was achieved by treating cells with 520 nM doramapimod (MedChemExpress, MCE, Rahway, NJ, USA) for 24 h. To induce Nqo1 activity, cells were treated with 2-HBA (MCE) at a concentration of 0.6 μM for 24 h. The siRNA of Rack1 (RiboBio, Guangzhou, China) was used at a concentration of 80 nM, with a treatment time of 24–36 h. .. Intracellular ferrous iron was detected using the FerroOrange fluorescent probe (Dojindo, Beijing, China).

Activity Assay:

Article Title: p38 mitogen-activated protein kinase drives senescence in CD4 + T lymphocytes and increases their pathological potential
Article Snippet: The semi-quantitative analysis was performed using the ImageJ/Fiji software (NIH). .. To neutralize the p38 MAPK activity, the H 2 O 2 -exposed CD4 + T lymphocytes were cultured for 4 days in the presence of the p38 MAPK-specific inhibitor BIRB-796 500 nM (MedChemExpress), with DMSO used as the vehicle control. .. To assess the involvement of autophagy, CD4+ T lymphocytes were co-treated with BIRB-796 and the autophagy inhibitor Bafilomycin A1 200 nM (Invitrogen) under the same culture conditions.

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Article Title: p38 mitogen-activated protein kinase drives senescence in CD4 + T lymphocytes and increases their pathological potential.
Article Snippet: The semi-quantitative analysis was performed using the ImageJ/Fiji software (NIH).

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