ovcar 8 (ATCC)

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ATCC ovcar 8
Ovcar 8, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 7646 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ovcar+8/SK-OV-3/us12612361-142-109-143
Average 99 stars, based on 7646 article reviews

ovcar 8 - by Bioz Stars, 2026-09

99/100 stars

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Inhibition:

Article Title: Synthesis of New Thiazole-Privileged Chalcones as Tubulin Polymerization Inhibitors with Potential Anticancer Activities
Article Snippet: Among the tested derivatives, compound 2h was the most potent derivative, with broad cytotoxic effect (negative value) against LOX IMVI, RXF 393, UO-31, HCC-2998, SF-539, MDA-MB-468, OVCAR-3, KM12, U251, NCI-H23, SK-MEL-5, NCI-H522, ACHN, UACC-62, T-47D, CAKI-1, SK-MEL-28, MCF7, MALME-3M, NCI-H226, SW-620, OVCAR-5, MDA-MB-435, HCT-15, NCI-H460, SN12C, COLO 205, MDA-MB-231/ATCC, BT-549, SR, 786-0, and HCT-116 cancer cells with growth percentages of −98.99, −91.92, −89.63, −86.72, −85.88, −82.86, −79.48, −78.4, −75.99, −72.77, −68.8, −58.81, −58.35, −56.71, −56.63, −56.46, −47.02, −45.42, −42.94, −41.9, −37.8, −37.4, −36.95, −36.42, −30.68, −25.64, −24.88, −21.75, −17.58, −14.03, −10.99, −10.85, and −6.25, respectively. .. Also, it displayed remarkable cytostatic action (positive value) against EKVX, HOP-62, M14, SF-295, HL-60(TB), NCI/ADR-RES, PC-3, DU-145, RPMI-8226, UACC-257, IGROV1, SNB-19, OVCAR-4, MOLT-4, OVCAR-8, K-562, CCRF-CEM, SK-MEL-2, A549/ATCC, HT29, HS 578T, SF-268, NCI-H322M, SK-OV-3, and A498 cancer cells with growth inhibition percentages of 0.65, 0.68, 1.86, 4.14, 5.25, 8.19, 8.43, 8.55, 9.39, 9.4, 10.16, 10.38, 13.05, 13.31, 13.44, 13.77, 13.78, 16.88, 19.51, 20.35, 24.47, 27.46, 28.92, 44.61, and 8.87, respectively. ..

Multiple Displacement Amplification:

Article Title: Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding
Article Snippet: .. The disclosed compounds may be effective in inhibiting cell proliferation of one or more types of cancer cells including: lymphoma cells, such as; bladder cancer cells, such as; multiple myeloma cells, such as MM.1S cells; leukemia cells, such as CCRF-CEM, HL-60 (TB), MOLT-4, RPMI-8226 and SR; non-small lung cancer cells, such as A549/ATCC, EKVX, HOP-62, HOP-92, NCI-H226, NCI-H23, NCI-H322M, NCI-H460 and NCI-H522; colon cancer cells, such as COLO 205, HCC-2998, HCT-116, HCT-15, HT29, KM12 and SW-620; CNS: SF-268, SF-295, SF-539, SNB-19, SNB-75 and U251; melanoma cancer cells, such as LOX IMVI, MALME-3M, M14, MDA-MB-435, SK-MEL-2, SK-MEL-28, SK-MEL-5, UACC-257 and UACC-62; ovarian cancer cells, such as IGR-OV1, OVCAR-3, OVCAR-4, OVCAR-5, OVCAR-8, NCI/ADR-RES and SK—OV-3; renal cancer cells, such as 786-0, A498, ACHN, CAKI-1, RXF 393, SN12C, TK-10 and UO-31; prostate cancer cells, such as DU-145 and PC-3; and breast cancer cells, such as MCF7, MDA-MB-231/ATCC, MDA-MB-468, HS 578T, BT-549 and T-47D. ..

Article Title: TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
Article Snippet: .. NCI-H226 (ATCC Cat# CRL-5826; RRID:CVCL_1544; male), OVCAR-8 (NCI-Frederick Cancer DCTD; RRID:CVCL_1629; female), NCI-H290 (NIH Naval Hospital; RRID:CVCL_A555; male), MDA-MB-231 (ATCC Cat# HTB-26; RRID:CVCL_0062; female), VMRC-LCD (JCRB/HSRRB Cat# JCRB0814; RRID:CVCL_1787; male), ES-2 (ATCC Cat# CRL-1978; RRID:CVCL_3509; female), QGP-1 (JCRB/HSRRB Cat# JCRB0183; RRID:CVCL_3143; male), MSTO-211H (ATCC Cat# CRL-2081; CVCL_1430; male); these cells were cultured in RPMI with 10% FBS and 10 U/ml Penicillin-Streptomycin (GIBCO 15140122). .. 293T cells (ATCC Cat# CRL-3216, RRID:CVCL_0063; female) were cultured in DMEM with 10% FBS and 10 U/ml Penicillin-Streptomycin (GIBCO 15140122).

other:

Article Title: Anticancer Potential of Piericidin A1 and Derivatives Isolated From Streptomyces sp. Associated With Palythoa variabilis From Brazilian Reefs.
Article Snippet: The chromatograms were trimmed, and assembled, and the consensus sequence was generated in Geneious Prime (Biomatters Ltd., New Zealand).

Cell Culture:

Article Title: Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors
Article Snippet: .. KURAMOCHI (RRID:CVCL1345), OVSAHO (RRID:CVCL_3114), OVCAR-3 (ATCC HTB-161), OVCAR-8 (RRID:CVCL_1629), CAOV3 (ATCC HTB-75), OV81.2 and HEYA8 (RRID:CVCL_8878) cell lines were used as models for high-grade serous ovarian carcinoma and cultured in DMEM (MT10013CV, Corning)/Ham’s F-12 (MT10080CV, Corning) media (1:1) supplemented by 10% (V/V) of fetal bovine serum (FBS, Gibco), 100 U/ml penicillin, and 100 mg/ml streptomycin (Corning CellGro). ..

Incubation:

Article Title: HOOK2 downregulation compromises the tumorigenic and stemness properties of ovarian cancer cells by increasing endoplasmic reticulum stress.
Article Snippet: .. SKOV-3, OVCAR-8 and hTERT FT 282 cell lines were obtained from the ATCC commercial repository and maintained in RPMI (AQmedia: Sigma) (OVCAR-8, SKOV-3) or DMEM/F12 50:50 mix (AQmedia: Sigma) AR TI CL E IN P RE SS (hTERT FT 282) with 10% fetal bovine serum (FBS) (Gibco), penicillin, streptomycin and fungizone (Sigma) and incubated at 37 °C in 5% CO2 in a humidified atmosphere. ..

Review