other:Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 41 42 43 TABLE S4: Estimated parameters (best fit and [95%-confidence interval]) as well as model calibration quality of 44 the GUTS-RED-IT (implementation: openGUTS MATLAB®) for 5 species 45 Species kD [1/d] mw [μg/L] Fs [-] hb [1/d] NRMSE [%] (< 50) NSE [-] (> 0.5) SPPE [%] (-50 to +50) C. carpio 0.450 [0.0884; 0.727] 3.55 [0.949; 4.70] 1.38 [1.17; 2.07] 0.00689 [0.000454; 0.0303] 3.6 1.0 -6.2 to 2.8 P. promelas 0.277 [0.209; 0.450] 3.46 [3.14; 3.78] 2.11 [1.29; 3.15] 0.00859 [0.00708; 0.0104] 8.2 0.87 -9.3 to 4.8 C. variegatus 0.479 [0.333; 0.513] 27.0 [22.0; 28.2] 1.05 [1.05; 1.29]a 1.00e-06 [1.00e-06; 0.0144]a 0.016 1.0 -3.5e-2 to 4.0e-4 O. mykiss 4.88 [1.38; 7.67] 9.76 [7.46; 11.4] 1.05 [1.05; 2.95]a 1.00e-06 [1.00e-06; 0.0132]a 0.035 1.0 -0.030 to 0 L. macrochirus 0.940 [0.559; 1.64] 25.2 [19.3; 32.4] 1.56 [1.24; 2.52] 1.00e-06 [1.00e-06; 0.0161]a 2.1 1.0 -0.70 to 0.089 Parameters Quality criteria kD = dominant rate constant NSE = Nash-Sutcliff model efficiency coefficient mw = median of threshold distribution NRMSE = Normalised root-means-square error Fs = factor spreadb SPPE = Survival-probability prediction error hb = background hazard rate a Upper 95% parameter CI has run into a boundary.
Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 82 83 Figure S4: LP50 comparison for GUTS-RED-IT implementations (circle = morse, triangle = openGUTS MATLAB®, 84 square = openGUTS standalone) across five different fish species: a) sheepshead minnow; b) common carp; 85 c) bluegill; d) rainbow trout; and e) fathead minnow (acute and ELS test) for exposure scenario B.
Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 88 89 90 91 Figure S5: LP50 comparison for GUTS-RED-SD implementations (circle = morse, triangle = openGUTS MATLAB®, 92 square = openGUTS standalone) across five different fish species: a) sheepshead minnow; b) common carp; 93 c) bluegill; d) rainbow trout; and e) fathead minnow (acute and ELS test) for exposure scenario C. For openGUTS 94 versions, predictions were conducted from the best fit (dot) and the parameter sample (95% confidence interval 95 - vertical line), for morse from the posterior distribution (median - dot and 95% credible intervals - vertical line).
Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 68 69 Figure S2: LP50 comparison for GUTS-RED-IT implementations (circle = morse, triangle = openGUTS MATLAB®, 70 square = openGUTS standalone) across five different fish species: a) sheepshead minnow; b) common carp; 71 c) bluegill; d) rainbow trout; and e) fathead minnow (acute and ELS test) for exposure scenario A.
Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 35 b factor spread Fs = 391/beta, where beta is the shape parameter of the log-logistic distribution (Jager and Ashauer 36 2018) 37 38 TABLE S3: Estimated parameters (best fit and [95%-confidence interval]) as well as model calibration quality of 39 the GUTS-RED-SD (implementation: openGUTS MATLAB®) for 5 species 40 Species kD [1/d] zw [μg/L] bw [L/(μg d)] hb [1/d] NRMSE [%] (< 50) NSE [-] (> 0.5) SPPE [%] (-50 to +50) C. carpio 1.00 [0.335; 2.16] 4.05 [1.67; 4.84] 1.41 [0.353; 4.14] 0.00684 [0.000497; 0.0301] 3.3 1.0 -4.5 to 2.7 P. promelas 2.00 [1.02; 5.05] 3.44 [3.25; 3.54] 0.214 [0.0974; 0.542] 0.00923 [0.00779; 0.0109] 9.0 0.85 -3.0 to 8.0 C. variegatus 0.509 [0.435; 0.805] 27.7 [22.2; 28.6] 210 [0.210; 2230]a 1.00e-06 [1.00e-06; 0.0144]a 0.001 1.0 0 to 0.00135 O. mykiss 144 [6.02; 144]b 9.53 [7.01; 9.79] 1.02 [0.139; 18600] 1.00e-06 [1.00e-06; 0.0137]a 6.0 0.98 -4.0e-4 to 8.9 L. macrochirus 3.17 [1.50; 144]a 21.8 [18.7; 22.8] 0.112 [0.0380; 0.291] 1.00e-06 [1.00e-06; 0.0162]a 2.7 1.0 -5.5e-3 to 2.0 Parameters Quality criteria kD = dominant rate constant NSE = Nash-Sutcliff model efficiency coefficient zw = threshold for effects NRMSE = Normalised root-means-square error bw = killing rate constant SPPE = Survival-probability prediction error hb = background hazard rate a Upper 95% parameter CI has run into a boundary.
Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles
Article Snippet: 74 75 76 77 Figure S3 LP50 comparison for GUTS-RED-SD implementations (circle = morse, triangle = openGUTS MATLAB®, 78 square = openGUTS standalone) across five different fish species: a) sheepshead minnow; b) common carp; 79 c) bluegill; d) rainbow trout; and e) fathead minnow (acute and ELS test) for exposure scenario B.
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![Model comparison for reduced general unified threshold models of survival of fathead minnow (GUTS‐RED‐stochastic death [SD]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐SD are dominant rate constant, threshold for effects, killing rate constant, and background mortality. For <t>openGUTS</t> versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. zw = threshold for effects; hb = background mortality; k D = dominant rate constant; bw = killing rate constant.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8144/pmc09328144/pmc09328144__ETC-41-1732-g002.jpg)
![Model comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐IT are dominant rate constant, median of the threshold distribution, threshold distribution shape parameter, and background mortality. For openGUTS versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. mw = median of the threshold distribution; hb = background mortality; k D = dominant rate constant; beta = threshold distribution shape parameter.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8144/pmc09328144/pmc09328144__ETC-41-1732-g003.jpg)
![Median lethal profile comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) implementations (circle = morse, triangle = openGUTS MATLAB®, square = openGUTS standalone) across five different fish species: sheepshead minnow, common carp, bluegill, rainbow trout, and fathead minnow (calibration was performed with acute and early life stage test) for exposure Scenario C. For openGUTS versions, the best fit (dot) and 95% confidence interval (vertical line) are displayed; for morse, the median (dot) and 95% credible intervals (vertical line) of the posterior distributions are displayed. LP50 = median lethal profile.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8144/pmc09328144/pmc09328144__ETC-41-1732-g001.jpg)
