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Article Title: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM
Article Snippet: The data that support the findings of this study are available to license from IBM (CCAE, MDCD, MDCR), Optum (OCEDM, OEHR), and IQVIA (IMRD).



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Description of databases from the Observational Health Data Sciences and Informatics network included in the study.

Journal: BMJ Medicine

Article Title: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM

doi: 10.1136/bmjmed-2023-000651

Figure Lengend Snippet: Description of databases from the Observational Health Data Sciences and Informatics network included in the study.

Article Snippet: The data that support the findings of this study are available to license from IBM (CCAE, MDCD, MDCR), Optum (OCEDM, OEHR), and IQVIA (IMRD).

Techniques:

Proportional incident use of second line antihyperglycaemic drugs in United States national databases, United States health system. CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Centre; DPP-4i=dipeptidyl peptidase-4 inhibitors; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; GLP-1 RA=glucagon-like peptide-1 receptor agonist; HIC=Health Informatics Centre at the University of Dundee; JHM=Johns Hopkins Medicine; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart-Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SGLT2i=sodium-glucose cotransporter 2 inhibitor; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; SU=sulfonylurea; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Journal: BMJ Medicine

Article Title: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM

doi: 10.1136/bmjmed-2023-000651

Figure Lengend Snippet: Proportional incident use of second line antihyperglycaemic drugs in United States national databases, United States health system. CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Centre; DPP-4i=dipeptidyl peptidase-4 inhibitors; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; GLP-1 RA=glucagon-like peptide-1 receptor agonist; HIC=Health Informatics Centre at the University of Dundee; JHM=Johns Hopkins Medicine; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart-Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SGLT2i=sodium-glucose cotransporter 2 inhibitor; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; SU=sulfonylurea; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Article Snippet: The data that support the findings of this study are available to license from IBM (CCAE, MDCD, MDCR), Optum (OCEDM, OEHR), and IQVIA (IMRD).

Techniques:

Proportional first incident use of glucagon-like peptide-1 receptor agonists as second line therapy after metformin in patients with established cardiovascular disease, and patients without established cardiovascular disease. ALPD=Australia Longitudinal Patient Database Practice Profile; CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Center; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; GLP-1 RA=glucagon-like peptide-1 receptor agonist; HIC=Health Informatics Centre at the University of Dundee; HKHA=Hong Kong Hospital Authority; IMRD=UK-IQVIA Medical Research Data; JHM=Johns Hopkins Medicine; MDCD=IBM Health MarketScan Multi-State Medicaid Database; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart - Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Journal: BMJ Medicine

Article Title: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM

doi: 10.1136/bmjmed-2023-000651

Figure Lengend Snippet: Proportional first incident use of glucagon-like peptide-1 receptor agonists as second line therapy after metformin in patients with established cardiovascular disease, and patients without established cardiovascular disease. ALPD=Australia Longitudinal Patient Database Practice Profile; CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Center; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; GLP-1 RA=glucagon-like peptide-1 receptor agonist; HIC=Health Informatics Centre at the University of Dundee; HKHA=Hong Kong Hospital Authority; IMRD=UK-IQVIA Medical Research Data; JHM=Johns Hopkins Medicine; MDCD=IBM Health MarketScan Multi-State Medicaid Database; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart - Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Article Snippet: The data that support the findings of this study are available to license from IBM (CCAE, MDCD, MDCR), Optum (OCEDM, OEHR), and IQVIA (IMRD).

Techniques:

Proportional first incident use of sodium-glucose Cctransporter 2 inhibitors as second line therapy after metformin in (A) patients with established cardiovascular disease, and (B) patients without established cardiovascular disease. ALPD=Australia Longitudinal Patient Database Practice Profile; CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Centre; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; HIC=Health Informatics Centre at the University of Dundee; HKHA=Hong Kong Hospital Authority; IMRD=UK-IQVIA Medical Research Data; JHM=Johns Hopkins Medicine; MDCD=IBM Health MarketScan Multi-State Medicaid Database; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart–Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SGLT2i=sodium-glucose cotransporter 2 inhibitor; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Journal: BMJ Medicine

Article Title: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM

doi: 10.1136/bmjmed-2023-000651

Figure Lengend Snippet: Proportional first incident use of sodium-glucose Cctransporter 2 inhibitors as second line therapy after metformin in (A) patients with established cardiovascular disease, and (B) patients without established cardiovascular disease. ALPD=Australia Longitudinal Patient Database Practice Profile; CCAE=IBM MarketScan Commercial Claims and Encounters Data; CUIMC=Columbia University Irving Medical Centre; FLPD=France Longitudinal Patient Database; GDA=Germany Disease Analyser; HIC=Health Informatics Centre at the University of Dundee; HKHA=Hong Kong Hospital Authority; IMRD=UK-IQVIA Medical Research Data; JHM=Johns Hopkins Medicine; MDCD=IBM Health MarketScan Multi-State Medicaid Database; MDCR=IBM Health MarketScan Medicare Supplemental and Coordination of Benefits Database; OCEDM=Optum Clinformatics Extended Data Mart–Date of Death; OEHR=Optum de-identified Electronic Health Record Dataset; SGLT2i=sodium-glucose cotransporter 2 inhibitor; SIDIAP=Information System for Research in Primary Care; STARR=Stanford Medicine; USOC=United States Open Claims; VA=Department of Veterans Affairs Healthcare System

Article Snippet: The data that support the findings of this study are available to license from IBM (CCAE, MDCD, MDCR), Optum (OCEDM, OEHR), and IQVIA (IMRD).

Techniques: