Journal: Pharmaceuticals
Article Title: Exploring Wound-Healing Genomic Machinery with a Network-Based Approach
doi: 10.3390/ph10020055
Figure Lengend Snippet: Plots of the TNF pathway node behaviors after the stimulation of Rigenera ® . The plot has been obtained with Odefy and it refers to the output of one Monte Carlo simulation. In detail, Rigenera ® autologous micro-graft targets in the pathway have been initialized to their expression values, while other network nodes are randomly set to 0 or 1 . The plot shows that the values of some genes, initially set to 0, have been increased by the Rigenera ® action, and vice versa. Panel ( a ) shows the behaviors of all network nodes; Panel ( b ) shows a subset of such node behaviors, in which Tnfrsf1a exhibits an increase, Itch a decrease, while Rigenera ® seems to not affect the behaviors of Traf2 and Jun (their output values are similar to the initial ones).
Article Snippet: Simulations were performed using the MATLAB-toolbox Odefy [ ].
Techniques: Expressing