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mda mb 231  (ATCC)
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Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue <t>bars)</t> <t>and</t> <t>MDA‐MB‐231</t> (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.
Mda Mb 231, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-231/MDA-MB-231/pmc13673301-91-6-8
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mda mb 231 - by Bioz Stars, 2026-10
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human breast adenocarcinoma mda mb 231  (ATCC)
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Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue <t>bars)</t> <t>and</t> <t>MDA‐MB‐231</t> (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.
Human Breast Adenocarcinoma Mda Mb 231, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 1 article reviews
human breast adenocarcinoma mda mb 231 - by Bioz Stars, 2026-10
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tnbc xenograft model mda mb 231  (ATCC)
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Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue <t>bars)</t> <t>and</t> <t>MDA‐MB‐231</t> (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.
Tnbc Xenograft Model Mda Mb 231, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-231/MDA-MB-231/pm42803936-97-9-13
Average 99 stars, based on 1 article reviews
tnbc xenograft model mda mb 231 - by Bioz Stars, 2026-10
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human breast cancer cell line mda mb 231  (ATCC)
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ATCC human breast cancer cell line mda mb 231
Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue <t>bars)</t> <t>and</t> <t>MDA‐MB‐231</t> (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.
Human Breast Cancer Cell Line Mda Mb 231, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mda-mb-231/MDA-MB-231/10__1038_slash_s41467___026___78085___9-489-6-27
Average 99 stars, based on 1 article reviews
human breast cancer cell line mda mb 231 - by Bioz Stars, 2026-10
99/100 stars
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Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue bars) and MDA‐MB‐231 (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.

Journal: International Journal of Genomics

Article Title: Single‐Cell Multiomics Integration Reveals Cell Trajectories and Regulatory Networks in Breast Cancer Progression

doi: 10.1155/ijog/9324717

Figure Lengend Snippet: Quantitative RT‐PCR validation of key subtype marker genes in breast cancer cell lines. Bar chart of relative mRNA expression levels of six marker genes (ERBB2, ESR1, PGR, KRT5, VIM, and CDH1) normalized to GAPDH in MCF‐7 (luminal, blue bars) and MDA‐MB‐231 (basal/TNBC, red bars) cell lines. Error bars represent standard deviation from three independent biological replicates. Significance brackets indicate: ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 by two‐tailed Student′s t ‐test. Luminal markers ERBB2, ESR1, PGR, and CDH1 show significantly higher expression in MCF‐7, whereas basal/mesenchymal markers KRT5 and VIM are significantly enriched in MDA‐MB‐231, validating single‐cell sequencing findings.

Article Snippet: MCF‐7 (luminal, ER+/PR+/HER2‐, ATCC HTB‐22) and MDA‐MB‐231 (basal/TNBC, ATCC HTB‐26) cell lines were cultured in DMEM supplemented with 10% FBS, 100 U/mL penicillin, and 100 μ g/mL streptomycin at 37°C/5% CO2.

Techniques: Quantitative RT-PCR, Biomarker Discovery, Marker, Expressing, Standard Deviation, Two Tailed Test, Single-Cell Sequencing