mcf 12a human non tumorigenic breast cell line (ATCC)

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ATCC mcf 12a human non tumorigenic breast cell line

Assessment of Stizolophus balsamita extract, stizolin, stizolicin, and izospiciformin on breast cancer cells’ viability. MCF7, MDA-MB-231, SK-BR-3, <t>and</t> <t>MCF-12A</t> cells were treated for 24 (A) , 48 (B) , or 72 (C) h with a wide range of concentrations of studied compounds, i.e., 1–100 µg/mL. The mean ± SD from three experiments is shown. Statistically significant differences versus control samples are shown: *p < 0.05; p < 0.005; *p < 0.001.

Mcf 12a Human Non Tumorigenic Breast Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 296 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mcf+12a+cell+lines/MCF-12A/pmc13199166-75-19-32
Average 96 stars, based on 296 article reviews

mcf 12a human non tumorigenic breast cell line - by Bioz Stars, 2026-10

96/100 stars

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1) Product Images from "Selective biological activity of parthenolide derivatives — stizolin, stizolicin, and izospiciformin — isolated from the leaves of Stizolophus balsamita , in different breast cancer molecular subtypes in vitro"

Article Title: Selective biological activity of parthenolide derivatives — stizolin, stizolicin, and izospiciformin — isolated from the leaves of Stizolophus balsamita , in different breast cancer molecular subtypes in vitro

Journal: Frontiers in Pharmacology

doi: 10.3389/fphar.2026.1799963

Assessment of Stizolophus balsamita extract, stizolin, stizolicin, and izospiciformin on breast cancer cells’ viability. MCF7, MDA-MB-231, SK-BR-3, and MCF-12A cells were treated for 24 (A) , 48 (B) , or 72 (C) h with a wide range of concentrations of studied compounds, i.e., 1–100 µg/mL. The mean ± SD from three experiments is shown. Statistically significant differences versus control samples are shown: *p < 0.05; p < 0.005; *p < 0.001.

Figure Legend Snippet: Assessment of Stizolophus balsamita extract, stizolin, stizolicin, and izospiciformin on breast cancer cells’ viability. MCF7, MDA-MB-231, SK-BR-3, and MCF-12A cells were treated for 24 (A) , 48 (B) , or 72 (C) h with a wide range of concentrations of studied compounds, i.e., 1–100 µg/mL. The mean ± SD from three experiments is shown. Statistically significant differences versus control samples are shown: *p < 0.05; p < 0.005; *p < 0.001.

Techniques Used: Control

Control:

Article Title: KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β-catenin signaling pathway.
Article Snippet: .. The human normal breast epithelial MCF‐10A and MCF‐12A cell lines, which have been widely used as control cell lines for BC cell lines (16,17), and BC MCF‐7, ZR‐75‐1, HCC‐1937 and MDA‐MB‐436 cell lines, were purchased from the American Type Culture Collection (ATCC). .. Cells were cultured at 37 ̊C in DMEM (Thermo Fisher Scientific, Inc.) supplemented with 10% FBS (Gibco; Thermo Fisher Scientific, Inc.), in a humid atmosphere with 5% CO2.

Article Title: KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β-catenin signaling pathway
Article Snippet: .. The human normal breast epithelial MCF-10A and MCF-12A cell lines, which have been widely used as control cell lines for BC cell lines ( , ), and BC MCF-7, ZR-75-1, HCC-1937 and MDA-MB-436 cell lines, were purchased from the American Type Culture Collection (ATCC). .. Cells were cultured at 37°C in DMEM (Thermo Fisher Scientific, Inc.) supplemented with 10% FBS (Gibco; Thermo Fisher Scientific, Inc.), in a humid atmosphere with 5% CO 2 .

Multiple Displacement Amplification:

Article Title: Highly potent TACC3 inhibitor as a novel anticancer drug candidate
Article Snippet: .. Materials and Methods Cell Culture and Reagents MDA-MB-436, MDA-MB-157 and MCF-12A cell lines were obtained from ATCC. ..

Article Title: Role of aromatase activation on sodium arsenite-induced proliferation, migration, and invasion of MDA-MB-231 and MDA-MB-453 breast cancer cell lines.
Article Snippet: Arsenic is an endocrine disruptor that promotes breast cancer (BCa) development.. Estrogen synthesis, through aromatase activation, is essential for BCa promotion and progression through activating the G-coupled estrogen receptor 1 (GPER1), regulating rapid nongenomic effects involved in cell proliferation and migration of BCa cells.. Herein, was studied the role of aromatase activation and the GPER1 pathway on sodium arsenite-induced promotion and progression of MDA-MB-231 and MDA-MB-453 BCa cell lines.

Cell Culture:

Article Title: Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer
Article Snippet: .. MCF-10A and MCF-12A cell lines were obtained from American Type Culture Collection (ATCC) and cultured in mammary epithelial cell growth basal medium with single quots supplements and growth factors (#Lonza CC-4136). .. Cells were treated with the medium-chain fatty acid sodium octanoate (OA; Sigma # C5038) dissolved in PBS; and long-chain fatty acid Linoleic acid (LA; Sigma # L8134) complexed with fatty acid-free BSA (Roche 10775835001).

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