Review




Structured Review

OpGen Inc mapsolver software (v.2.1.1;
Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with <t>MapSolver</t> (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.
Mapsolver Software (V.2.1.1;, supplied by OpGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mapsolver+v%2E2%2E1%2E1+software/mapsolver+software/pmc04888882-248-9-12
Average 90 stars, based on 1 article reviews
mapsolver software (v.2.1.1; - by Bioz Stars, 2026-10
90/100 stars

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1) Product Images from "Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics"

Article Title: Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics

Journal: mSphere

doi: 10.1128/mSphere.00036-16

Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with MapSolver (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.
Figure Legend Snippet: Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with MapSolver (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.

Techniques Used: Sequencing

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In Silico:

Article Title: Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 26 of sequenced E. coli isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Article Title: Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 19 sequenced S. aureus isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Sequencing:

Article Title: Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 26 of sequenced E. coli isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Article Title: Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 19 sequenced S. aureus isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Transformation Assay:

Article Title: Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 26 of sequenced E. coli isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Article Title: Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 19 sequenced S. aureus isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Software:

Article Title: Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 26 of sequenced E. coli isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).

Article Title: Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers
Article Snippet: The optical maps of the studied strains were then compared with the in silico restriction maps of 19 sequenced S. aureus isolates whose sequence genomes were available in GenBank and transformed by using the MapSolver v.2.1.1 software (OpGen SA).



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OpGen Inc mapsolver software (v.2.1.1;
Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with <t>MapSolver</t> (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.
Mapsolver Software (V.2.1.1;, supplied by OpGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mapsolver+v%2E2%2E1%2E1+software/mapsolver+software/pmc04888882-248-9-12
Average 90 stars, based on 1 article reviews
mapsolver software (v.2.1.1; - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
OpGen Inc mapsolver v.2.1.1 software
Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with <t>MapSolver</t> (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.
Mapsolver V.2.1.1 Software, supplied by OpGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mapsolver+v%2E2%2E1%2E1+software/mapsolver+software/pmc04512213-43-34-37
Average 90 stars, based on 1 article reviews
mapsolver v.2.1.1 software - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with MapSolver (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.

Journal: mSphere

Article Title: Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics

doi: 10.1128/mSphere.00036-16

Figure Lengend Snippet: Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with MapSolver (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.

Article Snippet: Restriction map alignments between different strains were generated using MapSolver software (v.2.1.1; OpGen, Gaithersburg, MD).

Techniques: Sequencing