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lectins lta  (Vector Laboratories)


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    Vector Laboratories lectins lta
    Lectins Lta, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 96/100, based on 405 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lta+lectin/Biotinylated+Lotus+Tetragonolobus+Lectin+(LTL)/pm40375122-77-1-4
    Average 96 stars, based on 405 article reviews
    lectins lta - by Bioz Stars, 2026-09
    96/100 stars

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    Staining:

    Article Title: Galectin-8 counteracts folic acid-induced acute kidney injury and prevents its transition to fibrosis.
    Article Snippet: Acute kidney injury (AKI), characterized by a sudden decline in kidney function involving tubular damage and epithelial cell death, can lead to progressive tissue fibrosis and chronic kidney disease due to interstitial fibroblast activation and tissue repair failures that lack direct treatments.. After an AKI episode, surviving renal tubular cells undergo cycles of dedifferentiation, proliferation and redifferentiation while fibroblast activity increases and then declines to avoid an exaggerated extracellular matrix deposition.. Appropriate tissue recovery versus pathogenic fibrotic progression depends on fine-tuning all these processes.



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    ( A ) Cystic index represented as the percentage of cystic area per kidney section from 1-, 3-, 7-, and 10-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. Each data point represents one animal (n ≥ 3). Statistical analysis was performed using two-way ANOVA and is presented as the mean ± SEM. ( B ) Representative images of <t>LTA+</t> and mG+ cystic tubules in Cdh16Cre;ROSA mT/mG ;Fbxw7 f/f (middle and right panels) and Cdh16Cre;ROSA mT/mG (left panel) mice. White arrows show cystic mG+ tubules that are LTA + . Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( C–J ) Representative images of immunofluorescence staining for ( C , D ) proximal tubule marker, Lotus <t>tetragonolobus</t> agglutinin (LTA), ( E , F ) thick ascending limb of the loop of Henle marker, NKCC2, and ( G , H ) collecting duct marker, Dolichos biflorus agglutinin (DBA) from 3- and 7-month-old kidneys of Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. White arrows show dilated or cystic tubular segments of the kidney that are positive for ( C , D ) LTA (green), ( E , F ) NKCC2 (pink), and ( G , H ) DBA (red). Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( I , J ) Pie chart displaying the percentage of cystic tubules distributed across different kidney segments from 3- and 7-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice ( n ≥ 3).
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    ( A ) Cystic index represented as the percentage of cystic area per kidney section from 1-, 3-, 7-, and 10-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. Each data point represents one animal (n ≥ 3). Statistical analysis was performed using two-way ANOVA and is presented as the mean ± SEM. ( B ) Representative images of <t>LTA+</t> and mG+ cystic tubules in Cdh16Cre;ROSA mT/mG ;Fbxw7 f/f (middle and right panels) and Cdh16Cre;ROSA mT/mG (left panel) mice. White arrows show cystic mG+ tubules that are LTA + . Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( C–J ) Representative images of immunofluorescence staining for ( C , D ) proximal tubule marker, Lotus <t>tetragonolobus</t> agglutinin (LTA), ( E , F ) thick ascending limb of the loop of Henle marker, NKCC2, and ( G , H ) collecting duct marker, Dolichos biflorus agglutinin (DBA) from 3- and 7-month-old kidneys of Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. White arrows show dilated or cystic tubular segments of the kidney that are positive for ( C , D ) LTA (green), ( E , F ) NKCC2 (pink), and ( G , H ) DBA (red). Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( I , J ) Pie chart displaying the percentage of cystic tubules distributed across different kidney segments from 3- and 7-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice ( n ≥ 3).
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    ( A ) Cystic index represented as the percentage of cystic area per kidney section from 1-, 3-, 7-, and 10-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. Each data point represents one animal (n ≥ 3). Statistical analysis was performed using two-way ANOVA and is presented as the mean ± SEM. ( B ) Representative images of <t>LTA+</t> and mG+ cystic tubules in Cdh16Cre;ROSA mT/mG ;Fbxw7 f/f (middle and right panels) and Cdh16Cre;ROSA mT/mG (left panel) mice. White arrows show cystic mG+ tubules that are LTA + . Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( C–J ) Representative images of immunofluorescence staining for ( C , D ) proximal tubule marker, Lotus <t>tetragonolobus</t> agglutinin (LTA), ( E , F ) thick ascending limb of the loop of Henle marker, NKCC2, and ( G , H ) collecting duct marker, Dolichos biflorus agglutinin (DBA) from 3- and 7-month-old kidneys of Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. White arrows show dilated or cystic tubular segments of the kidney that are positive for ( C , D ) LTA (green), ( E , F ) NKCC2 (pink), and ( G , H ) DBA (red). Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( I , J ) Pie chart displaying the percentage of cystic tubules distributed across different kidney segments from 3- and 7-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice ( n ≥ 3).
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    Image Search Results


    ( A ) Cystic index represented as the percentage of cystic area per kidney section from 1-, 3-, 7-, and 10-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. Each data point represents one animal (n ≥ 3). Statistical analysis was performed using two-way ANOVA and is presented as the mean ± SEM. ( B ) Representative images of LTA+ and mG+ cystic tubules in Cdh16Cre;ROSA mT/mG ;Fbxw7 f/f (middle and right panels) and Cdh16Cre;ROSA mT/mG (left panel) mice. White arrows show cystic mG+ tubules that are LTA + . Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( C–J ) Representative images of immunofluorescence staining for ( C , D ) proximal tubule marker, Lotus tetragonolobus agglutinin (LTA), ( E , F ) thick ascending limb of the loop of Henle marker, NKCC2, and ( G , H ) collecting duct marker, Dolichos biflorus agglutinin (DBA) from 3- and 7-month-old kidneys of Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. White arrows show dilated or cystic tubular segments of the kidney that are positive for ( C , D ) LTA (green), ( E , F ) NKCC2 (pink), and ( G , H ) DBA (red). Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( I , J ) Pie chart displaying the percentage of cystic tubules distributed across different kidney segments from 3- and 7-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice ( n ≥ 3).

    Journal: EMBO Molecular Medicine

    Article Title: SOX9-dependent fibrosis drives renal function in nephronophthisis

    doi: 10.1038/s44321-025-00233-3

    Figure Lengend Snippet: ( A ) Cystic index represented as the percentage of cystic area per kidney section from 1-, 3-, 7-, and 10-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. Each data point represents one animal (n ≥ 3). Statistical analysis was performed using two-way ANOVA and is presented as the mean ± SEM. ( B ) Representative images of LTA+ and mG+ cystic tubules in Cdh16Cre;ROSA mT/mG ;Fbxw7 f/f (middle and right panels) and Cdh16Cre;ROSA mT/mG (left panel) mice. White arrows show cystic mG+ tubules that are LTA + . Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( C–J ) Representative images of immunofluorescence staining for ( C , D ) proximal tubule marker, Lotus tetragonolobus agglutinin (LTA), ( E , F ) thick ascending limb of the loop of Henle marker, NKCC2, and ( G , H ) collecting duct marker, Dolichos biflorus agglutinin (DBA) from 3- and 7-month-old kidneys of Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice. White arrows show dilated or cystic tubular segments of the kidney that are positive for ( C , D ) LTA (green), ( E , F ) NKCC2 (pink), and ( G , H ) DBA (red). Nuclei are stained with DAPI (blue). Scale bar: 50 µm. ( I , J ) Pie chart displaying the percentage of cystic tubules distributed across different kidney segments from 3- and 7-month-old Fbxw7 f/f and Cdh16Cre;Fbxw7 f/f mice ( n ≥ 3).

    Article Snippet: Fluorescein (1:1000; Vector Laboratories FL-1321) or Cy5 (1:1000; USBIO 518482) conjugated Lotus Tetragonolobus Lectin (LTA) and Rhodamine conjugated Dolichos Biflorus Agglutinin (DBA) (1:1000; Vector Laboratories RL-1032-2), was added to co-stain proximal tubules and collecting ducts, respectively, in the secondary antibody solution wherever needed.

    Techniques: Staining, Immunofluorescence, Marker