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ld information  (Genomics England)

 
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    Genomics England ld information
    Ld Information, supplied by Genomics England, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ld+information/england+from+genomics+imputation+information+ld+the+ukbb/pm42162431-554-6-11
    Average 86 stars, based on 1 article reviews
    ld information - by Bioz Stars, 2026-11
    86/100 stars

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    Selection:

    Article Title: Genetic analysis of circulating metabolic traits in 619,372 individuals.
    Article Snippet: .. For instrument selection, we used the LD information from the UKBB Genomics England imputation (Pan-UKBB EUR subset, n = 413,897) and used greedy pruning strategy to only retain variants with P < 5 × 10−8 and r2 < 0.01. ..



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    ld information  (Genomics England)
    86
    Genomics England ld information
    Ld Information, supplied by Genomics England, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ld+information/england+from+genomics+imputation+information+ld+the+ukbb/pm42162431-554-6-11
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    reference identifiers additional information other ld columns 130 042 901 miltenyi biotec other cd4  (Miltenyi Biotec)
    96
    Miltenyi Biotec reference identifiers additional information other ld columns 130 042 901 miltenyi biotec other cd4
    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
    Reference Identifiers Additional Information Other Ld Columns 130 042 901 Miltenyi Biotec Other Cd4, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    supplementary information s2 lds sample buffer  (Thermo Fisher)
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
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    linkage disequilibrium ld block information  (Thermo Fisher)
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
    Linkage Disequilibrium Ld Block Information, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page

    Journal: eLife

    Article Title: Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

    doi: 10.7554/elife.69975

    Figure Lengend Snippet: Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page

    Article Snippet: DOI: https://doi.org/10.7554/eLife.69975 36 of 37 Appendix 1—key resources table continued Reagent type (species) or resource Designation Source or reference Identifiers Additional information Other LD Columns 130-042-901 Miltenyi Biotec Other CD4 (L3T4) MicroBeads, mouse 1 x 2 mL 130-117-043 Miltenyi Biotec Other CD8a (Ly-2) MicroBeads, mouse 130-117-044 Miltenyi Biotec Other DAPI (4’,6- Diamidino-2Phenylindole, Dihydrochloride) D1306 Thermo Fisher Other Precision Count Beads 424902 Biolegend Other RBC Lysis Buffer (10X) 420301 Biolegend Other Liquid DAB+ K3468 Dako Liu, Yu, Xu, et al. eLife 2021;10:e69975.

    Techniques: Control, Double Knockout