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hydroxypropyl methylcellulose  (Colorcon Inc)

 
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    Colorcon Inc hydroxypropyl methylcellulose
    Hydroxypropyl Methylcellulose, supplied by Colorcon Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hydroxypropyl+methylcellulose/hydroxypropyl+methylcellulose/pmc12908058-55-0-7
    Average 86 stars, based on 1 article reviews
    hydroxypropyl methylcellulose - by Bioz Stars, 2026-09
    86/100 stars

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    other:

    Article Title: A Quality-by-Design-Driven Framework for Process Variability Control and Design Space Establishment in Wet Granulation Systems
    Article Snippet: Hydroxypropyl cellulose (HPC-L) was supplied by Nippon Soda Co., Ltd. (Tokyo, Japan), and hydroxypropyl methylcellulose (HPMC K15M) was purchased from Colorcon, Inc. (Suwon, Republic of Korea).

    Article Title: Development and Evaluation of Curcumin-Loaded Mucoadhesive Buccal Films Using Green Deep Eutectic Solvents via Design of Experiments.
    Article Snippet: Hydroxypropyl methylcellulose (HPMC K100, 100 mPa·s in a 2% aqueous solution at 20 ◦C; Colorcon, Poughkeepsie, NY, USA) was kindly gifted by Colorcon, and Kollicoat® IR was kindly provided by BASF SE (Ludwigshafen, Germany).

    Article Title: Sustained Ocular Delivery of Moxifloxacin-Ufasomes-Laden In Situ Gel for Keratitis Management.
    Article Snippet: Hydroxypropyl methylcellulose (HPMC K4M, 4000 cps) was provided as gift from Colorcon (Dartford, UK).

    Article Title: Development and Evaluation of Curcumin-Loaded Mucoadhesive Buccal Films Using Green Deep Eutectic Solvents via Design of Experiments
    Article Snippet: Hydroxypropyl methylcellulose (HPMC K100, 100 mPa·s in a 2% aqueous solution at 20 °C; Colorcon, Poughkeepsie, NY, USA) was kindly gifted by Colorcon, and Kollicoat ® IR was kindly provided by BASF SE (Ludwigshafen, Germany).

    Article Title: Liposomal design and shear shielding of colloidal matrices control drug release.
    Article Snippet: The drug release of liposomes is strongly modulated by mechanical stress, yet the interplay between carrier properties and the surrounding colloidal environment remains difficult to resolve experimentally due to the challenge of preserving shear conditions and carrier microenvironment during measurement.. Here, we address this limitation using the Dispersion Releaser, a USP-referenced dialysis-based platform that enables in situ quantification of release under continuous shear.. Computational fluid dynamics (CFD) simulations were used to map flow regimes across 25-100 rotations per minute (RPM), informing the selection of 25 RPM (low shear) and 75 RPM (high shear) for subsequent experiments.

    Article Title: Sustained Ocular Delivery of Moxifloxacin–Ufasomes-Laden In Situ Gel for Keratitis Management
    Article Snippet: Hydroxypropyl methylcellulose (HPMC K4M, 4000 cps) was provided as gift from Colorcon (Dartford, UK).

    Starch:

    Article Title: A multidimensional strategy combining surface science, release kinetics, and morphology to guide sustained-release tablet development
    Article Snippet: This study investigates the relationship between surface thermodynamic properties and drug release kinetics in galantamine–HPMC compressed matrices.. An integrated experimental strategy was applied, encompassing excipient compatibility (FTIR, DSC), particle and flow characterization, surface energy analysis (contact angle, OWRK model), kinetic modeling, and morphological documentation (SEM, real-time imaging).. FTIR and DSC confirmed molecular dispersion and absence of incompatibilities.



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    Image Search Results


    Assessment of therapeutic efficacy of developed NRG formulation and comparison free NRG. Comparison of paw volume(a), and paw diameter(b). Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w /w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles).

    Journal: International Journal of Pharmaceutics: X

    Article Title: Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

    doi: 10.1016/j.ijpx.2026.100527

    Figure Lengend Snippet: Assessment of therapeutic efficacy of developed NRG formulation and comparison free NRG. Comparison of paw volume(a), and paw diameter(b). Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w /w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles).

    Article Snippet: Hydroxypropyl methylcellulose (HPMC; K4M) was supplied by Dow Chemical Company in Midland, MI.

    Techniques: Drug discovery, Formulation, Comparison, Negative Control

    X-ray radiographic of ankle joints of hind legs from different animal groups. Negative control rats show a normal structure of the joint; the Positive control group shows the induced arthritis with swelling of soft tissue on the hind paw (red circle), joint destruction, bone erosion, and deformities. Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Journal: International Journal of Pharmaceutics: X

    Article Title: Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

    doi: 10.1016/j.ijpx.2026.100527

    Figure Lengend Snippet: X-ray radiographic of ankle joints of hind legs from different animal groups. Negative control rats show a normal structure of the joint; the Positive control group shows the induced arthritis with swelling of soft tissue on the hind paw (red circle), joint destruction, bone erosion, and deformities. Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Article Snippet: Hydroxypropyl methylcellulose (HPMC; K4M) was supplied by Dow Chemical Company in Midland, MI.

    Techniques: Negative Control, Positive Control

    Effects of different treatments on inflammatory biomarkers measured by ELISA: (a) mTOR, (b) IL-1β, (c) Lipid peroxidation (LPO, ex-pressed as MDA levels), (d) MMP3, (e) TNF-α, (f) NF-KB, (g) IL-6,qPCR expression gene 88 (MYD88)(h), thioredoxin interacting protein (TXNIP)(i), and B-cell lymphoma 2 (BCL-2)(j). Data are expressed as mean ± SD ( n = 10). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, and ns (not significant) versus the control group. Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles).

    Journal: International Journal of Pharmaceutics: X

    Article Title: Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

    doi: 10.1016/j.ijpx.2026.100527

    Figure Lengend Snippet: Effects of different treatments on inflammatory biomarkers measured by ELISA: (a) mTOR, (b) IL-1β, (c) Lipid peroxidation (LPO, ex-pressed as MDA levels), (d) MMP3, (e) TNF-α, (f) NF-KB, (g) IL-6,qPCR expression gene 88 (MYD88)(h), thioredoxin interacting protein (TXNIP)(i), and B-cell lymphoma 2 (BCL-2)(j). Data are expressed as mean ± SD ( n = 10). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, and ns (not significant) versus the control group. Abbreviations: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles).

    Article Snippet: Hydroxypropyl methylcellulose (HPMC; K4M) was supplied by Dow Chemical Company in Midland, MI.

    Techniques: Enzyme-linked Immunosorbent Assay, Expressing, Control, Negative Control

    H&E histological assessment (a) and quantitative scoring of cartilage surface damage (b), cellularity loss (c), and tidemark integrity (d) in CFA-induced RA rats treated GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). H&E, X:100 scale bar 100 μm & X:400 bar 50 μm. Data are presented as mean ± SD (n = 10). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 versus the negative.

    Journal: International Journal of Pharmaceutics: X

    Article Title: Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

    doi: 10.1016/j.ijpx.2026.100527

    Figure Lengend Snippet: H&E histological assessment (a) and quantitative scoring of cartilage surface damage (b), cellularity loss (c), and tidemark integrity (d) in CFA-induced RA rats treated GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). H&E, X:100 scale bar 100 μm & X:400 bar 50 μm. Data are presented as mean ± SD (n = 10). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 versus the negative.

    Article Snippet: Hydroxypropyl methylcellulose (HPMC; K4M) was supplied by Dow Chemical Company in Midland, MI.

    Techniques: Negative Control

    (a)Immunohistochemical photomicrographs of lung sections stained for Transforming Growth Factor-Beta (TGF-β) expression in different groups. Severe positive TGF-β expression is indicated in neoplastic cells (arrows). Group assignments: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). (b) Quantitative analysis of TGF-β immunoreactivity, presented as reaction area percentage (%) IHC counterstained with Mayer's hematoxylin—low magnification X: 100 bar 100 μ and high magnification 400 bar 50 μ. Data are expressed as mean ± SD (n = 10). **p < 0.01, ****p < 0.0001 versus the negative control group.

    Journal: International Journal of Pharmaceutics: X

    Article Title: Hyaluronic acid microneedle patch for transdermal delivery of naringin-loaded PEGylated terpesomes in a rat model of rheumatoid arthritis: Modulation TGF-β1, oxidative stress, and inflammation

    doi: 10.1016/j.ijpx.2026.100527

    Figure Lengend Snippet: (a)Immunohistochemical photomicrographs of lung sections stained for Transforming Growth Factor-Beta (TGF-β) expression in different groups. Severe positive TGF-β expression is indicated in neoplastic cells (arrows). Group assignments: GI (healthy negative control), GII (RA model, untreated), GIII (treated with Naringin gel containing 2% w/w HPMC), GIV (treated with Naringin-loaded terpesomes in gel with 2% w/w HPMC), and GV (treated with Naringin-loaded terpesomes incorporated in Hyaluronic acid microneedles). (b) Quantitative analysis of TGF-β immunoreactivity, presented as reaction area percentage (%) IHC counterstained with Mayer's hematoxylin—low magnification X: 100 bar 100 μ and high magnification 400 bar 50 μ. Data are expressed as mean ± SD (n = 10). **p < 0.01, ****p < 0.0001 versus the negative control group.

    Article Snippet: Hydroxypropyl methylcellulose (HPMC; K4M) was supplied by Dow Chemical Company in Midland, MI.

    Techniques: Immunohistochemical staining, Staining, Expressing, Negative Control