soluble vcam 1 svcam 1 (R&D Systems)
R&D Systems is a verified supplier 
R&D Systems manufactures this product 
94
Structured Review
R&D Systems
soluble vcam 1 svcam 1
Soluble Vcam 1 Svcam 1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 53 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+svcam/Human+VCAM-1%2FCD106+DuoSet+ELISA/pmc12790166-62-2-5
Average 94 stars, based on 53 article reviews
Soluble Vcam 1 Svcam 1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 53 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+svcam/Human+VCAM-1%2FCD106+DuoSet+ELISA/pmc12790166-62-2-5
Average 94 stars, based on 53 article reviews
soluble vcam 1 svcam 1 - by Bioz Stars,
2026-10
94/100 stars
Images
1) Product Images from "Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition"
Article Title: Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition
Journal: Annals of Clinical and Translational Neurology
doi: 10.1002/acn3.70207
Figure Legend Snippet: Blood biomarker dynamics during the annual 12‐week dosing gap. (A) NfL serum levels measured during SID (baseline, time point A), at the end of the 12‐week dosing gap (time point B), as well as 3 months post gap (time point C). (B) SVCAM‐1 serum levels measured during SID (baseline, time point A), at the end of the 12‐week dosing gap (time point B), as well as 3 months post gap (time point C). (C) SVCAM‐1 levels correlated to NTZ serum levels measured at baseline (green, time point A) and at the end of the 12‐week dosing gap (orange, time point B). Spearman (non‐parametric) analysis revealed a significant correlation ( p value < 0.0001).
Techniques Used: Biomarker Discovery
Figure Legend Snippet: The annual 12‐week dosing gap modulates the composition of CSF immune cells. (A) Quantification of CD45+ CSF immune cell counts per ml by flow cytometry at time points A and B from six patients. (B) UMAP plots of CSF scRNAseq data immune cell subsets from nine patients at time points A (left) and B (right), annotated by aCSF. (C–I) Quantification of immune cell subset clusters as a percentage of cells within each sample from CSF of healthy donors (HD), treatment‐naïve MS (MS), and NTZ‐treated MS patients on SID (baseline, time point A) as well as after the A12WG (time point B). Only subsets with a significant increase from time points A and B are shown. (J–L) The scatterplots depict correlations between absolute changes from time points A and B of immune cell subset proportions in the CSF and serum concentrations of sVCAM‐1. Only significant positive correlations are shown. (M–N) The scatterplots depict correlations between absolute changes from time points A and B of immune cell subset proportions in the CSF and serum concentrations of NfL. Only significant correlations are shown. Statistical difference is indicated * p < 0.05. The circled dots indicate patients with MRI features after the treatment gap (patient #6, black; patient #8, blue).
Techniques Used: Flow Cytometry, Tandem Mass Spectroscopy
Figure Legend Snippet: Mechanism of action of natalizumab. (A) with a scenario where all VLA‐4‐expressing immune cells are blocked from trafficking into the CNS. Theoretical scenario (B) where some cells are blocked from trafficking into the CNS, while others are not. When VLA‐4 binds to VCAM‐1, sVCAM‐1 can be produced.
Techniques Used: Expressing, Produced
Related Articles
Enzyme-linked Immunosorbent Assay:Article Title: Lower serum kallistatin level is associated with 28-day mortality in patients with septic shock. Article Snippet: Contents lists available at ScienceDirect Journal of Critical Care j ourna l homepage: www. journa ls .e lsev ie r .com/ journa l -o f -c r i t i ca l -ca re Lower serum kallistatin level is associated with 28-day mortality in patients with septic shock Taegyun Kim, MDa, Gil Joon Suh, MD, PhD a,b,⁎, Woon Yong Kwon, MD, PhD a,b, Kyung Su Kim, MD, PhD a, Yoon Sun Jung, MDa, So Mi Shin, MDc a Department of Emergency Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea b Department of Emergency Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea c Division of Critical Care Medicine, Department of Emergency Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea ⁎ Corresponding author at: Department of Emerge University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 030 E-mail addresses: kimtaegyun@snuh.org (T. Kim), suh kwy711@snu.ac.kr (W.Y.. Kwon). https://doi.org/10.1016/j.jcrc.2018.09.008 0883-9441/© 2018 Elsevier Inc. All rights reserved. a b s t r a c t a r t i c l e i n f o Keywords: Purpose: Investigation for whether serum levels of kallistatin, vascular cell adhesion molecule-1 (VCAM-1), and E-selectin are associated with outcomes in patients with septic shock Material and methods: Biomarker levels were measured using blood samples from patients with septic shock at admission, 24 h, and 72 h and from healthy volunteers.. The primary outcome was 28-day mortality. Article Title: Association between the simultaneous decrease in the levels of soluble vascular cell adhesion molecule-1 and S100 protein and good neurological outcomes in cardiac arrest survivors Article Snippet: .. The Human ICAM-1/CD54 Allele-specific Quantikine ELISA Kit (DCD540; R&D Systems, Minneapolis, MN, USA), Article Title: Serum Metabolomic Analysis of Coronary Heart Disease Patients with Stable Angina Pectoris Subtyped by Traditional Chinese Medicine Diagnostics Reveals Biomarkers Relevant to Personalized Treatments Article Snippet: .. The Human ET-1 QuantiGlo ELISA Kit (lot QET00B), Human sICAM-1/CD54 Allele-specific Quantikine ELISA Kit (lot DCD540), and Article Title: Endothelial Function and Arterial Stiffness Should Be Measured to Comprehensively Assess Obstructive Sleep Apnea in Clinical Practice Article Snippet: Serum tumor necrosis factor-alpha (TNF-α) levels were measured using the IMMULITE 1000 Automatic Chemiluminescence Immunoassay (Siemens Medical, USA). .. Serum vascular cell adhesion molecule (VCAM), endothelin-1 (ET-1), and plasma vascular endothelial growth factor (VEGF) were measured using the Article Title: Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier Article Snippet: Mouse plasma samples were used to measure soluble VCAM-1 using VCAM-1 ELISA kit (Raybiotech, ELM-VCAM-1) according to manual instructions. .. Soluble VCAM1 was measured in human plasma samples using the Article Title: Anti-cardiolipin and increased serum adhesion molecule levels in patients with aggressive periodontitis. Article Snippet: Background: We observed that a significant proportion of patients with periodontitis have elevated serum levels of b2-glycoprotein-I–dependent anti-cardiolipin (anti-CL).. These prothrombotic autoantibodies, commonly found to be elevated in patients with systemic lupus erythematosus and the antiphospholipid syndrome, are associated with adverse pregnancy outcomes, such as fetal involution, prematurity, and low birth weight, and with cardiovascular sequelae, such as atherosclerosis, stroke, and myocardial infarction.. Anti-CL is known to promote vascular inflammation and thrombosis. Article Title: Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 Article Snippet: Mouse plasma samples were used to measure soluble VCAM-1 using VCAM-1 ELISA kit (Raybiotech, ELM-VCAM-1) according to manual instructions. .. Soluble VCAM1 was measured in human plasma samples using the Article Title: Linking Complement Activation, Coagulation, and Neutrophils in Transplant-Associated Thrombotic Microangiopathy. Article Snippet: 1Department of Hematology, BMT Unit, G. Papanikolaou Hospital, Thessaloniki, Greece 2Laboratory of Molecular Hematology, Democritus University of Thrace, Alexandroupolis, Greece 3Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States 4 Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany 5National Center for Tumor Diseases, Partner Site Dresden, of the German Cancer Research Center, Heidelberg and of the Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, and of the Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany Clinical Proteomics:Article Title: Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier Article Snippet: Mouse plasma samples were used to measure soluble VCAM-1 using VCAM-1 ELISA kit (Raybiotech, ELM-VCAM-1) according to manual instructions. .. Soluble VCAM1 was measured in human plasma samples using the Article Title: Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 Article Snippet: Mouse plasma samples were used to measure soluble VCAM-1 using VCAM-1 ELISA kit (Raybiotech, ELM-VCAM-1) according to manual instructions. .. Soluble VCAM1 was measured in human plasma samples using the |