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pinp  (Elabscience Biotechnology)


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    Structured Review

    Elabscience Biotechnology pinp
    ( A ) Scatter plots of <t>PINP</t> <t>and</t> <t>PIIINP</t> plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.
    Pinp, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pinp/Human+P%E2%85%A0NP+(Procollagen+%E2%85%A0+N-Terminal+Propeptide)+ELISA+Kit/pmc12346474-174-19-22
    Average 94 stars, based on 12 article reviews
    pinp - by Bioz Stars, 2026-11
    94/100 stars

    Images

    1) Product Images from "Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia"

    Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

    Journal: International Journal of Molecular Sciences

    doi: 10.3390/ijms26157032

    ( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.
    Figure Legend Snippet: ( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.

    Techniques Used: Clinical Proteomics

    ( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.
    Figure Legend Snippet: ( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.

    Techniques Used: Clinical Proteomics

    Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.
    Figure Legend Snippet: Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.

    Techniques Used: Clinical Proteomics

    ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.
    Figure Legend Snippet: ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.

    Techniques Used:

    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: Life quality of men with ankylosing spondylitis: association with the disease course and the structural and functional state of bone tissue
    Article Snippet: .. The biochemical bone synthesis markers (osteocalcin and procollagen type I N-propeptide (PINP)) were evaluated by the immunoenzyme method, using the "N-MID Osteocalcin ELISA Kit" (Immunodiagnostic Systems, UK) and "Human PINP (Procollagen I N-Terminal Propeptide) ELISA Kit" (Elabscience, USA). .. The bone resorption marker (N-terminal telopeptide (NTx)) was assayed by the immunoenzyme method, using the "Human NTXI" kit (Elabscience, USA, catalog No: E-EL-H0836, Lot: 31DCADXW39) according to the producer’s specifications.



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    Comparison of demographic and clinical characteristics between r-axSpA with and without fatty lesions
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    Elabscience Biotechnology procollagen i n terminal propeptide
    Liraglutide (LIR) regulated streptozotocin (STZ)-induced bone metabolism imbalance and activation of neutrophil extracellular traps (NETs). Weight changes in rats were monitored weekly (A); the levels of serum insulin (B); and fasting blood glucose (FBG) (C) were detected; the serum levels of alkaline phosphatase (ALP) (D); osteocalcin (OCN) (E); procollagen I N-terminal <t>propeptide</t> (PINP) (F); tartrate-resistant acid phosphatase (TRACP) (G); and CTX-1 (H) were assessed using the corresponding assay kits; expression of cit-H3 in rat femur tissues was determined via immunofluorescence staining, scale bar = 20 μm (I); western blotting assays detected the expression of Sirtuin-1 (SIRT1) and NETs formation markers [cit-H3, myeloperoxidase (MPO), NE, and PAD4] in femur tissues, with GAPDH serving as the reference gene (J); quantitative analysis of the protein expressions (K). * P < 0.05, ** P < 0.01. All data are presented as means ± SD.
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    https://www.bioz.com/product/human+pinp/Human+PINP+(Procollagen+I+N-terminal+Propeptide+)+CLIA+Kit/pmc11892751-49-16-30
    Average 93 stars, based on 1 article reviews
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    Image Search Results


    ( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.

    Journal: International Journal of Molecular Sciences

    Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

    doi: 10.3390/ijms26157032

    Figure Lengend Snippet: ( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.

    Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

    Techniques: Clinical Proteomics

    ( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.

    Journal: International Journal of Molecular Sciences

    Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

    doi: 10.3390/ijms26157032

    Figure Lengend Snippet: ( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.

    Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

    Techniques: Clinical Proteomics

    Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.

    Journal: International Journal of Molecular Sciences

    Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

    doi: 10.3390/ijms26157032

    Figure Lengend Snippet: Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.

    Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

    Techniques: Clinical Proteomics

    ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.

    Journal: International Journal of Molecular Sciences

    Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

    doi: 10.3390/ijms26157032

    Figure Lengend Snippet: ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.

    Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

    Techniques:

    Comparison of demographic and clinical characteristics between r-axSpA with and without fatty lesions

    Journal: Arthritis Research & Therapy

    Article Title: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

    doi: 10.1186/s13075-025-03479-x

    Figure Lengend Snippet: Comparison of demographic and clinical characteristics between r-axSpA with and without fatty lesions

    Article Snippet: Serum levels of sclerostin (E-EL-H1544c, Elabscience, Wuhan, China), osteoprotegerin (OPG) (CHE0074, 4Abio, Beijing, China), procollagen I N-terminal propeptide (PINP) (E-EL-H0185c, Elabscience, Wuhan, China), cross linked C-telopeptide of type I collagen (CTX-I) (E-EL-H0835c, Elabscience, Wuhan, China) and osteocalcin (OC) (E-EL-H1343c, Elabscience, Wuhan, China) were measured with a specific sandwich enzyme-linked immunosorbent assay (ELISA).

    Techniques: Comparison

    Comparison of bone turnover markers levels between r-axSpA with and without fatty lesions. The serum levels of sclerostin were significantly lower in r-axSpA patients with fatty lesions than in those without fatty lesions ( p < 0.001). No significant differences were observed in terms of OPG, PINP, CTX-I or OC between two groups

    Journal: Arthritis Research & Therapy

    Article Title: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

    doi: 10.1186/s13075-025-03479-x

    Figure Lengend Snippet: Comparison of bone turnover markers levels between r-axSpA with and without fatty lesions. The serum levels of sclerostin were significantly lower in r-axSpA patients with fatty lesions than in those without fatty lesions ( p < 0.001). No significant differences were observed in terms of OPG, PINP, CTX-I or OC between two groups

    Article Snippet: Serum levels of sclerostin (E-EL-H1544c, Elabscience, Wuhan, China), osteoprotegerin (OPG) (CHE0074, 4Abio, Beijing, China), procollagen I N-terminal propeptide (PINP) (E-EL-H0185c, Elabscience, Wuhan, China), cross linked C-telopeptide of type I collagen (CTX-I) (E-EL-H0835c, Elabscience, Wuhan, China) and osteocalcin (OC) (E-EL-H1343c, Elabscience, Wuhan, China) were measured with a specific sandwich enzyme-linked immunosorbent assay (ELISA).

    Techniques: Comparison

    Univariate and multivariate analysis between CBM scores and clinical variables and biomarkers in r-axSpA with fatty lesions

    Journal: Arthritis Research & Therapy

    Article Title: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

    doi: 10.1186/s13075-025-03479-x

    Figure Lengend Snippet: Univariate and multivariate analysis between CBM scores and clinical variables and biomarkers in r-axSpA with fatty lesions

    Article Snippet: Serum levels of sclerostin (E-EL-H1544c, Elabscience, Wuhan, China), osteoprotegerin (OPG) (CHE0074, 4Abio, Beijing, China), procollagen I N-terminal propeptide (PINP) (E-EL-H0185c, Elabscience, Wuhan, China), cross linked C-telopeptide of type I collagen (CTX-I) (E-EL-H0835c, Elabscience, Wuhan, China) and osteocalcin (OC) (E-EL-H1343c, Elabscience, Wuhan, China) were measured with a specific sandwich enzyme-linked immunosorbent assay (ELISA).

    Techniques:

    Liraglutide (LIR) regulated streptozotocin (STZ)-induced bone metabolism imbalance and activation of neutrophil extracellular traps (NETs). Weight changes in rats were monitored weekly (A); the levels of serum insulin (B); and fasting blood glucose (FBG) (C) were detected; the serum levels of alkaline phosphatase (ALP) (D); osteocalcin (OCN) (E); procollagen I N-terminal propeptide (PINP) (F); tartrate-resistant acid phosphatase (TRACP) (G); and CTX-1 (H) were assessed using the corresponding assay kits; expression of cit-H3 in rat femur tissues was determined via immunofluorescence staining, scale bar = 20 μm (I); western blotting assays detected the expression of Sirtuin-1 (SIRT1) and NETs formation markers [cit-H3, myeloperoxidase (MPO), NE, and PAD4] in femur tissues, with GAPDH serving as the reference gene (J); quantitative analysis of the protein expressions (K). * P < 0.05, ** P < 0.01. All data are presented as means ± SD.

    Journal: Iranian Journal of Pharmaceutical Research : IJPR

    Article Title: The Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Liraglutide Regulates Sirtuin-1-Mediated Neutrophil Extracellular Traps to Improve Diabetes-Induced Bone Metabolism Imbalance

    doi: 10.5812/ijpr-148139

    Figure Lengend Snippet: Liraglutide (LIR) regulated streptozotocin (STZ)-induced bone metabolism imbalance and activation of neutrophil extracellular traps (NETs). Weight changes in rats were monitored weekly (A); the levels of serum insulin (B); and fasting blood glucose (FBG) (C) were detected; the serum levels of alkaline phosphatase (ALP) (D); osteocalcin (OCN) (E); procollagen I N-terminal propeptide (PINP) (F); tartrate-resistant acid phosphatase (TRACP) (G); and CTX-1 (H) were assessed using the corresponding assay kits; expression of cit-H3 in rat femur tissues was determined via immunofluorescence staining, scale bar = 20 μm (I); western blotting assays detected the expression of Sirtuin-1 (SIRT1) and NETs formation markers [cit-H3, myeloperoxidase (MPO), NE, and PAD4] in femur tissues, with GAPDH serving as the reference gene (J); quantitative analysis of the protein expressions (K). * P < 0.05, ** P < 0.01. All data are presented as means ± SD.

    Article Snippet: Serum levels of alkaline phosphatase (ALP, D799817-0500, Sangon, Shanghai, China), osteocalcin (OCN, D731045-0096, Sangon, Shanghai, China), procollagen I N-terminal propeptide (PINP, D731148-0096, Sangon, Shanghai, China), tartrate-resistant acid phosphatase (TRACP, E-EL-R0939, Elabscience, Wuhan, China), and c-terminal telopeptide of type 1 collagen (CTX-1, D731151-0096, Sangon, Shanghai, China) were measured using ELISA kits, following each manufacturer's instructions.

    Techniques: Activation Assay, Expressing, Immunofluorescence, Staining, Western Blot

    Knockdown of sirtuin-1 (SIRT1) regulated liraglutide (LIR)-inhibited oxidative stress and inflammation in vivo. The serum pro-inflammatory factors interleukin 6 (IL-6) (A); and TNF-α (B; as well as the anti-inflammatory factors IL-10 (C); and TGF-β (D); were detected using the corresponding assay kits. The levels of malondialdehyde (MDA) (E); and superoxide dismutase (SOD) (F) were assessed through ELISA kits; the serum levels of alkaline phosphatase (ALP) (G); OCN (H); procollagen I N-terminal propeptide (PINP) (I); tartrate-resistant acid phosphatase (TRACP) (J); and CTX-1 (K) were assessed using the corresponding assay kits. * P < 0.05, ** P < 0.01. ns = non-significant. All data are presented as means ± SD.

    Journal: Iranian Journal of Pharmaceutical Research : IJPR

    Article Title: The Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Liraglutide Regulates Sirtuin-1-Mediated Neutrophil Extracellular Traps to Improve Diabetes-Induced Bone Metabolism Imbalance

    doi: 10.5812/ijpr-148139

    Figure Lengend Snippet: Knockdown of sirtuin-1 (SIRT1) regulated liraglutide (LIR)-inhibited oxidative stress and inflammation in vivo. The serum pro-inflammatory factors interleukin 6 (IL-6) (A); and TNF-α (B; as well as the anti-inflammatory factors IL-10 (C); and TGF-β (D); were detected using the corresponding assay kits. The levels of malondialdehyde (MDA) (E); and superoxide dismutase (SOD) (F) were assessed through ELISA kits; the serum levels of alkaline phosphatase (ALP) (G); OCN (H); procollagen I N-terminal propeptide (PINP) (I); tartrate-resistant acid phosphatase (TRACP) (J); and CTX-1 (K) were assessed using the corresponding assay kits. * P < 0.05, ** P < 0.01. ns = non-significant. All data are presented as means ± SD.

    Article Snippet: Serum levels of alkaline phosphatase (ALP, D799817-0500, Sangon, Shanghai, China), osteocalcin (OCN, D731045-0096, Sangon, Shanghai, China), procollagen I N-terminal propeptide (PINP, D731148-0096, Sangon, Shanghai, China), tartrate-resistant acid phosphatase (TRACP, E-EL-R0939, Elabscience, Wuhan, China), and c-terminal telopeptide of type 1 collagen (CTX-1, D731151-0096, Sangon, Shanghai, China) were measured using ELISA kits, following each manufacturer's instructions.

    Techniques: Knockdown, In Vivo, Enzyme-linked Immunosorbent Assay