fluorogenic hdac4 assay kit (BPS Bioscience)
Structured Review
Fluorogenic Hdac4 Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hdac4+fluorogenic+assay+kit/HDAC4+Fluorogenic+Assay+Kit/10__4103_slash_apjtb__apjtb_622_25-93-6-10
Average 94 stars, based on 24 article reviews
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Activity Assay:Article Title: β-hydroxybutyrate impairs nasopharyngeal carcinoma cell aggressiveness via histone deacetylase 4 inhibition Article Snippet: Background Cancer stem cell phenotype confers tumor aggressiveness in multiple malignancies, including nasopharyngeal carcinoma (NPC).. Many studies supported that β-hydroxybutyrate (BHB), a ketone body, acts as an epigenetic factor with an anticancer effect.. Nevertheless, the effects of BHB on NPC remain elusive. Binding Assay:Article Title: Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344. Article Snippet: Epigenetic modifiers provide a new target for the development of anti-cancer drugs.. The eraser histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that targets various non-histone proteins such as transcription factors, nuclear receptors, cytoskeletal proteins, DNA repair proteins, and molecular chaperones.. Therefore, it became an attractive target for cancer treatment. |
