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fluorogenic hdac4 assay kit  (BPS Bioscience)


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    Structured Review

    BPS Bioscience fluorogenic hdac4 assay kit
    Fluorogenic Hdac4 Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hdac4+fluorogenic+assay+kit/HDAC4+Fluorogenic+Assay+Kit/10__4103_slash_apjtb__apjtb_622_25-93-6-10
    Average 94 stars, based on 24 article reviews
    fluorogenic hdac4 assay kit - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Activity Assay:

    Article Title: β-hydroxybutyrate impairs nasopharyngeal carcinoma cell aggressiveness via histone deacetylase 4 inhibition
    Article Snippet: Background Cancer stem cell phenotype confers tumor aggressiveness in multiple malignancies, including nasopharyngeal carcinoma (NPC).. Many studies supported that β-hydroxybutyrate (BHB), a ketone body, acts as an epigenetic factor with an anticancer effect.. Nevertheless, the effects of BHB on NPC remain elusive.

    Binding Assay:

    Article Title: Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
    Article Snippet: Epigenetic modifiers provide a new target for the development of anti-cancer drugs.. The eraser histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that targets various non-histone proteins such as transcription factors, nuclear receptors, cytoskeletal proteins, DNA repair proteins, and molecular chaperones.. Therefore, it became an attractive target for cancer treatment.



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    BPS Bioscience hdac4 fluorogenic assay kit
    ( A ) Antennal and whole-mount brain staining of Gr63a-Gal4 flies. Flies were exposed to diacetyl (headspace from 10 –2 soln) or air for 2–5 d. Brains and antenna were dissected on the indicated days, fixed, and then stained for neuropil marker nc82 (red) and anti-GFP (green). Magnification 25 x. ( B ) Mean of ab1C neurons expressing GFP after indicated days of odor exposure. d4on = 2,3-butanedione. n = 6, error bars = SEM. Schematic chemical structures of diacetyl, β-hydroxybutyrate, and sodium butyrate. ( C ) Dose–activity curves of class I HDACs: HDAC1, HDAC2, HDAC3, HDAC8, and class II HDAC6 treated with various concentrations of diacetyl. Percentage of HDAC activity is relative to the activity of each enzyme without diacetyl. IC50s are indicated in the chart areas. Error bars = SEM, n = 4–5. ( D ) Representative structures of odorants that inhibit HDACs (left), and average percentage inhibition of class I HDACs: HDAC1, HDAC3, and class II <t>HDAC4,</t> HDAC6 treated with 15 mM of indicated volatiles (right). Error bar = SD, each tested in duplicate.
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    Image Search Results


    ( A ) Antennal and whole-mount brain staining of Gr63a-Gal4 flies. Flies were exposed to diacetyl (headspace from 10 –2 soln) or air for 2–5 d. Brains and antenna were dissected on the indicated days, fixed, and then stained for neuropil marker nc82 (red) and anti-GFP (green). Magnification 25 x. ( B ) Mean of ab1C neurons expressing GFP after indicated days of odor exposure. d4on = 2,3-butanedione. n = 6, error bars = SEM. Schematic chemical structures of diacetyl, β-hydroxybutyrate, and sodium butyrate. ( C ) Dose–activity curves of class I HDACs: HDAC1, HDAC2, HDAC3, HDAC8, and class II HDAC6 treated with various concentrations of diacetyl. Percentage of HDAC activity is relative to the activity of each enzyme without diacetyl. IC50s are indicated in the chart areas. Error bars = SEM, n = 4–5. ( D ) Representative structures of odorants that inhibit HDACs (left), and average percentage inhibition of class I HDACs: HDAC1, HDAC3, and class II HDAC4, HDAC6 treated with 15 mM of indicated volatiles (right). Error bar = SD, each tested in duplicate.

    Journal: eLife

    Article Title: Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs

    doi: 10.7554/eLife.86823

    Figure Lengend Snippet: ( A ) Antennal and whole-mount brain staining of Gr63a-Gal4 flies. Flies were exposed to diacetyl (headspace from 10 –2 soln) or air for 2–5 d. Brains and antenna were dissected on the indicated days, fixed, and then stained for neuropil marker nc82 (red) and anti-GFP (green). Magnification 25 x. ( B ) Mean of ab1C neurons expressing GFP after indicated days of odor exposure. d4on = 2,3-butanedione. n = 6, error bars = SEM. Schematic chemical structures of diacetyl, β-hydroxybutyrate, and sodium butyrate. ( C ) Dose–activity curves of class I HDACs: HDAC1, HDAC2, HDAC3, HDAC8, and class II HDAC6 treated with various concentrations of diacetyl. Percentage of HDAC activity is relative to the activity of each enzyme without diacetyl. IC50s are indicated in the chart areas. Error bars = SEM, n = 4–5. ( D ) Representative structures of odorants that inhibit HDACs (left), and average percentage inhibition of class I HDACs: HDAC1, HDAC3, and class II HDAC4, HDAC6 treated with 15 mM of indicated volatiles (right). Error bar = SD, each tested in duplicate.

    Article Snippet: Commercial assay or kit , HDAC4 Fluorogenic Assay Kit , BPS Bioscience , 50064 , .

    Techniques: Staining, Marker, Expressing, Activity Assay, Inhibition

    Journal: eLife

    Article Title: Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs

    doi: 10.7554/eLife.86823

    Figure Lengend Snippet:

    Article Snippet: Commercial assay or kit , HDAC4 Fluorogenic Assay Kit , BPS Bioscience , 50064 , .

    Techniques: Sequencing, Activity Assay, Isolation, SYBR Green Assay, Protease Inhibitor, Western Blot