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marker isolectin b4  (Vector Laboratories)


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    Vector Laboratories marker isolectin b4
    Marker Isolectin B4, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 95/100, based on 648 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/marker isolectin b4/product/Vector Laboratories
    Average 95 stars, based on 648 article reviews
    marker isolectin b4 - by Bioz Stars, 2026-05
    95/100 stars

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    Refi - 10 reduces pathological neovascularization in oxygen-induced retinopathy (OIR) mice. ( A ) Refi-10 was administered intraperitoneally at P13, and retinas were analyzed at P17. ( B ) Analysis of retinal vasculature. ( a ) Representative <t>IB4-stained</t> whole-mount retinas from normal, OIR, OIR + Refi-10 (25 mg/kg), and OIR + Refi-10 (50 mg/kg) mice at P17. Avascular areas were circled in white . ( b ) Enlarged views of the boxed regions in a . Yellow arrows indicate vascular tufts. ( c ) Neovascularization regions were highlighted in white by ImageJ software. ( d , e ) The quantification of neovascular area and avascular area for each group. Scale bars = 1000 µm. ( C ) Representative H&E staining of retinal sections and quantification of endothelial cell nuclei anterior to the inner limiting membrane. Scale bars = 500 µm. Data are presented as mean ± SD ( n = 6 mice per group; * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).
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    Refi - 10 reduces pathological neovascularization in oxygen-induced retinopathy (OIR) mice. ( A ) Refi-10 was administered intraperitoneally at P13, and retinas were analyzed at P17. ( B ) Analysis of retinal vasculature. ( a ) Representative IB4-stained whole-mount retinas from normal, OIR, OIR + Refi-10 (25 mg/kg), and OIR + Refi-10 (50 mg/kg) mice at P17. Avascular areas were circled in white . ( b ) Enlarged views of the boxed regions in a . Yellow arrows indicate vascular tufts. ( c ) Neovascularization regions were highlighted in white by ImageJ software. ( d , e ) The quantification of neovascular area and avascular area for each group. Scale bars = 1000 µm. ( C ) Representative H&E staining of retinal sections and quantification of endothelial cell nuclei anterior to the inner limiting membrane. Scale bars = 500 µm. Data are presented as mean ± SD ( n = 6 mice per group; * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: An APE1 Redox Inhibitor Attenuates Pathological Retinal Vascularization by Suppressing FGF2 Angiogenic Signaling

    doi: 10.1167/iovs.67.3.47

    Figure Lengend Snippet: Refi - 10 reduces pathological neovascularization in oxygen-induced retinopathy (OIR) mice. ( A ) Refi-10 was administered intraperitoneally at P13, and retinas were analyzed at P17. ( B ) Analysis of retinal vasculature. ( a ) Representative IB4-stained whole-mount retinas from normal, OIR, OIR + Refi-10 (25 mg/kg), and OIR + Refi-10 (50 mg/kg) mice at P17. Avascular areas were circled in white . ( b ) Enlarged views of the boxed regions in a . Yellow arrows indicate vascular tufts. ( c ) Neovascularization regions were highlighted in white by ImageJ software. ( d , e ) The quantification of neovascular area and avascular area for each group. Scale bars = 1000 µm. ( C ) Representative H&E staining of retinal sections and quantification of endothelial cell nuclei anterior to the inner limiting membrane. Scale bars = 500 µm. Data are presented as mean ± SD ( n = 6 mice per group; * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).

    Article Snippet: Then, they were incubated with IB4 (1:100, DL-1208-.5; Vector Laboratories, USA) overnight at 4°C.

    Techniques: Staining, Software, Membrane