camp glosensor (20f) biosensor hek293g (Promega)
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Camp Glosensor (20f) Biosensor Hek293g, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glosensor+(20f)+camp+biosensor/hek293+cells/pmc11191602-68-9-18
Average 90 stars, based on 1 article reviews
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1) Product Images from "A novel and selective fluorescent ligand for the study of adenosine A 2B receptors"
Article Title: A novel and selective fluorescent ligand for the study of adenosine A 2B receptors
Journal: Pharmacology Research & Perspectives
doi: 10.1002/prp2.1223
Figure Legend Snippet: Effect of PSB603‐BY630 on Glosensor cAMP concentration‐response curves to the A 2B ‐selective agonist BAY 60–6583 in (A) HEK293G cells endogenously expressing A 2B R or (B) HEK293G cells overexpressing NLuc‐A 2B R. Concentration response curves were obtained in the absence and presence of 20 nM or 200 nM PSB603‐BY630. Values are mean ± S.E.M. of five separate experiments carried out in triplicate. Data represent peak luminescence response and are expressed as a percentage of the peak luminescence response to 3 μM BAY 60–6583 (in a) or 0.3 μM BAY 60–6583 (in b) obtained in the absence of antagonist in each individual experiment.
Techniques Used: Concentration Assay, Expressing
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Article Snippet: Stable mixedexpression populations of Article Title: A novel and selective fluorescent ligand for the study of adenosine A 2B receptors Article Snippet: A clonal HEK 293 cell line stably expressing the Article Title: S-nitrosylation is required for β 2 AR desensitization and experimental asthma. Article Snippet: In brief Post-translational modification of the b2AR by S-nitrosylation, resulting from receptor activation or direct modification, promotes receptor desensitization and caveolar internalization.. Preventing b2AR S-nitrosylation leads to sustained receptor signaling, thereby increasing cAMP, Erk, and NO. Mice with mutant b2AR refractory to S-nitrosylation are resistant to bronchoconstriction, inflammation, and development of asthma, suggesting that this newly identified desensitization mechanism may be targeted therapeutically in obstructive airway diseases. 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Article Snippet: Stable mixedexpression populations of Article Title: A novel and selective fluorescent ligand for the study of adenosine A 2B receptors Article Snippet: A clonal HEK 293 cell line stably expressing the Article Title: S-nitrosylation is required for β 2 AR desensitization and experimental asthma. Article Snippet: In brief Post-translational modification of the b2AR by S-nitrosylation, resulting from receptor activation or direct modification, promotes receptor desensitization and caveolar internalization.. Preventing b2AR S-nitrosylation leads to sustained receptor signaling, thereby increasing cAMP, Erk, and NO. Mice with mutant b2AR refractory to S-nitrosylation are resistant to bronchoconstriction, inflammation, and development of asthma, suggesting that this newly identified desensitization mechanism may be targeted therapeutically in obstructive airway diseases. 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Article Snippet: Stable mixedexpression populations of Article Title: A novel and selective fluorescent ligand for the study of adenosine A 2B receptors Article Snippet: A clonal HEK 293 cell line stably expressing the Article Title: S-nitrosylation is required for β 2 AR desensitization and experimental asthma. Article Snippet: In brief Post-translational modification of the b2AR by S-nitrosylation, resulting from receptor activation or direct modification, promotes receptor desensitization and caveolar internalization.. Preventing b2AR S-nitrosylation leads to sustained receptor signaling, thereby increasing cAMP, Erk, and NO. Mice with mutant b2AR refractory to S-nitrosylation are resistant to bronchoconstriction, inflammation, and development of asthma, suggesting that this newly identified desensitization mechanism may be targeted therapeutically in obstructive airway diseases. Article Title: Regionally selective cardiovascular responses to adenosine A 2A and A 2B receptor activation Article Snippet: A clonal HEK 293 cell line stably expressing the Article Title: Regionally selective cardiovascular responses to adenosine A <sub>2A</sub> and A <sub>2B</sub> receptor activation Article Snippet: A clonal HEK 293 cell line stably expressing the Article Title: Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity Article Snippet: Software:Article Title: Kinetic analysis of endogenous β 2 ‐adrenoceptor‐mediated cAMP GloSensor™ responses in HEK293 cells Article Snippet: HEK293 cells stably expressing the Article Title: Kinetic Analysis of the Early Signaling Steps of the Human Chemokine Receptor CXCR4. 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