fluorogenic dpp4 assay kit (BPS Bioscience)
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Fluorogenic Dpp4 Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluorogenic+dpp4+assay+kit/DPP4+Assay+Kit/10__1002_slash_slct__202505084-221-19-23
Average 93 stars, based on 6 article reviews
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In Vitro:Article Title: Design, synthesis and evaluation the bioactivities of novel 8‑methoxy-1-azacoumarin-3-carboxamide derivatives as anti-diabetic agents Article Snippet: In this study, a novel series of 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid and N-substituted 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxamide derivatives 2–10 were designed, synthesized, and screened for their in vitro α-amylase, α-glucosidase and DPP-4 enzymes resulting in effective anti-diabetic agents.. The research results showed that these compounds had significant inhibitory effects on both α-amylase and α-glucosidase enzymes.. Specifically, compound 4 demonstrated the most potency with IC50 of 30.50±2.67 and 19.98±3.24μM for α-glucosidase and α-amylase activities respectively, which was significantly more powerful than the drug Acarbose (IC50 = 48.97±3.42μM and 16.59±3.78μM). Article Title: Novel Imidazole–Chromen‐2‐One Derivatives: Design, Synthesis, and Biological Evaluation as Potential Antidiabetic and Antioxidant Agents Article Snippet: A series of novel imidazole–chromen-2one derivatives (6–11) were designed, synthesized, and evaluated using an analogbased drug design approach for their potential dual α-glucosidase/ α-amylase inhibitory and anti-inflammatory activities.. In vitro biochemical assays were conducted to assess enzyme inhibition and antioxidant potential.. Among all tested compounds, compound (11) exhibited the most potent α-glucosidase and α-amylase inhibitory effects, with IC50 values comparable to the standard drug Acarbose , indicating significant antidiabetic potential. Recombinant:Article Title: Design, synthesis and evaluation the bioactivities of novel 8‑methoxy-1-azacoumarin-3-carboxamide derivatives as anti-diabetic agents Article Snippet: In this study, a novel series of 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid and N-substituted 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxamide derivatives 2–10 were designed, synthesized, and screened for their in vitro α-amylase, α-glucosidase and DPP-4 enzymes resulting in effective anti-diabetic agents.. The research results showed that these compounds had significant inhibitory effects on both α-amylase and α-glucosidase enzymes.. Specifically, compound 4 demonstrated the most potency with IC50 of 30.50±2.67 and 19.98±3.24μM for α-glucosidase and α-amylase activities respectively, which was significantly more powerful than the drug Acarbose (IC50 = 48.97±3.42μM and 16.59±3.78μM). Article Title: Novel Imidazole–Chromen‐2‐One Derivatives: Design, Synthesis, and Biological Evaluation as Potential Antidiabetic and Antioxidant Agents Article Snippet: A series of novel imidazole–chromen-2one derivatives (6–11) were designed, synthesized, and evaluated using an analogbased drug design approach for their potential dual α-glucosidase/ α-amylase inhibitory and anti-inflammatory activities.. In vitro biochemical assays were conducted to assess enzyme inhibition and antioxidant potential.. Among all tested compounds, compound (11) exhibited the most potent α-glucosidase and α-amylase inhibitory effects, with IC50 values comparable to the standard drug Acarbose , indicating significant antidiabetic potential. Enzyme Inhibition Assay:Article Title: Design, synthesis and evaluation the bioactivities of novel 8‑methoxy-1-azacoumarin-3-carboxamide derivatives as anti-diabetic agents Article Snippet: In this study, a novel series of 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid and N-substituted 8‐methoxy-2-oxo-1,2-dihydroquinoline-3-carboxamide derivatives 2–10 were designed, synthesized, and screened for their in vitro α-amylase, α-glucosidase and DPP-4 enzymes resulting in effective anti-diabetic agents.. The research results showed that these compounds had significant inhibitory effects on both α-amylase and α-glucosidase enzymes.. Specifically, compound 4 demonstrated the most potency with IC50 of 30.50±2.67 and 19.98±3.24μM for α-glucosidase and α-amylase activities respectively, which was significantly more powerful than the drug Acarbose (IC50 = 48.97±3.42μM and 16.59±3.78μM). |

