eidd 1931 (MedChemExpress)
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eidd 1931
Eidd 1931, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 45 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/eidd+1931/EIDD-1931/pmc13107972-432-13-14
Average 95 stars, based on 45 article reviews
Eidd 1931, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 45 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/eidd+1931/EIDD-1931/pmc13107972-432-13-14
Average 95 stars, based on 45 article reviews
eidd 1931 - by Bioz Stars,
2026-09
95/100 stars
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1) Product Images from "De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus"
Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus
Journal: Cell reports
doi: 10.1016/j.celrep.2026.117074
Figure Legend Snippet: (A–E) Dose-response curves are shown for various small-molecule inhibitors against rGhV M-GS* (purple) and rNiV (orange). CHO-B2 cells were infected at an MOI of 0.05 and treated with (A) EIDD-2749, (B) GHP-88309, (C) remdesivir, (D) EIDD-1931 (molnupiravir active form), or (E) favipiravir (T-705). (F and G) Additional dose-response curves were measured in primary human astrocytes for (F) EIDD-2749 and (G) GHP-88309 under the same MOI and assay conditions. (H) Summary of half-maximal inhibitory concentrations (IC 50 ) derived from the dose-response curves in (A–G). Each row indicates the respective compound, virus, calculated IC 50 , corresponding 95% confidence interval, and the cell type in which the assay was performed. IC 50 values were determined in GraphPad Prism by nonlinear regression of (inhibitor) vs. normalized response. All experiments were conducted in biological triplicate. Error bars depict standard deviation.
Techniques Used: Infection, Derivative Assay, Virus, Standard Deviation
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Infection:Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: GHP-88309 , Sigma Aldrich , Cat# SML2997.GHP-88309 , Sigma Aldrich , Cat# SML2997.. Article Title: Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery Article Snippet: Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.. Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus. Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors. Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs normalized response. .. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo. Article Snippet: (“Favipiravir | C5H4FN3O2 | CID 492405 - PubChem,” n.d.) (FAV; T-705; B0084-463609 or HY-14768) was purchased from BOC Sciences or MedChem Express. .. Sofosbuvir (“Sofosbuvir |C22H29FN3O9P | CID 45375808 - PubChem,” n.d.) (SOF; GS-7977; HY-15005) and the cell-active metabolite of MPV, Derivative Assay:Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: GHP-88309 , Sigma Aldrich , Cat# SML2997.GHP-88309 , Sigma Aldrich , Cat# SML2997.. Article Title: Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery Article Snippet: Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.. Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus. Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors. Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs normalized response. .. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo. Article Snippet: (“Favipiravir | C5H4FN3O2 | CID 492405 - PubChem,” n.d.) (FAV; T-705; B0084-463609 or HY-14768) was purchased from BOC Sciences or MedChem Express. .. Sofosbuvir (“Sofosbuvir |C22H29FN3O9P | CID 45375808 - PubChem,” n.d.) (SOF; GS-7977; HY-15005) and the cell-active metabolite of MPV, Virus:Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: GHP-88309 , Sigma Aldrich , Cat# SML2997.GHP-88309 , Sigma Aldrich , Cat# SML2997.. Article Title: Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery Article Snippet: Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.. Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus. Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors. Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs normalized response. .. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo. Article Snippet: (“Favipiravir | C5H4FN3O2 | CID 492405 - PubChem,” n.d.) (FAV; T-705; B0084-463609 or HY-14768) was purchased from BOC Sciences or MedChem Express. .. Sofosbuvir (“Sofosbuvir |C22H29FN3O9P | CID 45375808 - PubChem,” n.d.) (SOF; GS-7977; HY-15005) and the cell-active metabolite of MPV, Standard Deviation:Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: GHP-88309 , Sigma Aldrich , Cat# SML2997.GHP-88309 , Sigma Aldrich , Cat# SML2997.. Article Title: Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery Article Snippet: Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.Molnupiravir (EIDD-2801) , MedChemExpress , Cat#HY-135853.. Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus. Article Snippet: All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.All drug inhibition assays were conducted in at least biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs. normalized response.. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors. Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors Article Snippet: BI-1347, CCT-251921, MSC-2530818 targeting CDK8, adefovir (AFV), brincidofovir (BCV), cidofovir (CDV), Article Title: De novo recovery of Ghana virus, an African bat Henipavirus, reveals differential tropism and attenuated pathogenicity compared to Nipah virus Article Snippet: biological triplicate, and IC 50 values were calculated in GraphPad Prism software by nonlinear regression of the [inhibitor] vs normalized response. .. Compounds employed in this study include EIDD-2749 (MedChemExpress, HY-146246), GHP-88309 (Sigma Aldrich, SML2997), Article Title: Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo. Article Snippet: (“Favipiravir | C5H4FN3O2 | CID 492405 - PubChem,” n.d.) (FAV; T-705; B0084-463609 or HY-14768) was purchased from BOC Sciences or MedChem Express. .. Sofosbuvir (“Sofosbuvir |C22H29FN3O9P | CID 45375808 - PubChem,” n.d.) (SOF; GS-7977; HY-15005) and the cell-active metabolite of MPV, |
