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mouse dpp4 cd26 antibody  (R&D Systems)


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    R&D Systems mouse dpp4 cd26 antibody
    Mouse Dpp4 Cd26 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 59 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dpp4/pm41984505-138-9-13?v=R%26D+Systems
    Average 93 stars, based on 59 article reviews
    mouse dpp4 cd26 antibody - by Bioz Stars, 2026-06
    93/100 stars

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    A to F, Oral glucose tolerance test (OGTT) performed after rosuvastatin (0.2 mg) treatment once daily for 27 days. A, Rosuvastatin-treated mice exhibit lower 60- and 90-minute plasma glucose levels, but B, area under the curve (AUC) was unaffected for glucose. C, Rosuvastatin-treated mice exhibit higher 5- and 60-minute plasma glucagon-like peptide 1 (GLP-1) levels, but D, AUC was unaffected for GLP-1. E, Rosuvastatin-treated mice had higher insulin secretion; AUC is presented in F. G, Long-term administration of rosuvastatin had no effect on the number of L cells in the jejunum. H to J, Long-term administration of rosuvastatin had no effect on intestinal messenger RNA expression of Gcg , Gip , Pyy , Pcsk1 , or Dpp4 in the H, duodenum; I, jejunum; or J, ileum. K, Long-term administration of rosuvastatin had no effect on β-cell mass. All parameters were assessed in 10 mice per group. Data are presented as box and whisker plots showing the minimum and maximum values (bottom and top error bars), the first (bottom of the box) and third (top of the box) quartiles and the median (middle of the box), or as a line graph showing the mean ± SEM. * P less than .05; ** P less than .01; and *** P less than .001 compared with vehicle-treated mice.

    Journal: The Journal of Clinical Endocrinology and Metabolism

    Article Title: HMGCR and Rosuvastatin Regulates GLP-1 Secretion and Expression—A Translational Study

    doi: 10.1210/clinem/dgaf608

    Figure Lengend Snippet: A to F, Oral glucose tolerance test (OGTT) performed after rosuvastatin (0.2 mg) treatment once daily for 27 days. A, Rosuvastatin-treated mice exhibit lower 60- and 90-minute plasma glucose levels, but B, area under the curve (AUC) was unaffected for glucose. C, Rosuvastatin-treated mice exhibit higher 5- and 60-minute plasma glucagon-like peptide 1 (GLP-1) levels, but D, AUC was unaffected for GLP-1. E, Rosuvastatin-treated mice had higher insulin secretion; AUC is presented in F. G, Long-term administration of rosuvastatin had no effect on the number of L cells in the jejunum. H to J, Long-term administration of rosuvastatin had no effect on intestinal messenger RNA expression of Gcg , Gip , Pyy , Pcsk1 , or Dpp4 in the H, duodenum; I, jejunum; or J, ileum. K, Long-term administration of rosuvastatin had no effect on β-cell mass. All parameters were assessed in 10 mice per group. Data are presented as box and whisker plots showing the minimum and maximum values (bottom and top error bars), the first (bottom of the box) and third (top of the box) quartiles and the median (middle of the box), or as a line graph showing the mean ± SEM. * P less than .05; ** P less than .01; and *** P less than .001 compared with vehicle-treated mice.

    Article Snippet: RNA was reverse-transcribed using RevertAid First Strand complementary DNA synthesis kit (Thermo Scientific). qPCR for Dpp4 (Mm00494538_m1), Gip (Mm00433601_m1) Hmgcr (Mm01282499_m1), Proglucagon ( Gcg ; Mm01269055_m1), Pcsk1 (Mm00479023_m1), Pyy (Mm00520715_m1), and 2 housekeeping genes ( Hprt [Mm03024075_m1] and Tbp [Mm01277042_m1]) was performed using TaqMan Expression PCR Master Mix (Life Technologies) using the ABI Prism 7900 HT system (Applied Biosystems).

    Techniques: Clinical Proteomics, RNA Expression, Whisker Assay