Review



il 6 catalog no d6050b elisa kits  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 96
      Buy from Supplier

    Structured Review

    R&D Systems il 6 catalog no d6050b elisa kits
    The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) <t>postoperative</t> <t>IL-6</t> in all 93 cases of patients after abdominal surgery.
    Il 6 Catalog No D6050b Elisa Kits, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 813 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 6 catalog no d6050b elisa kits/product/R&D Systems
    Average 96 stars, based on 813 article reviews
    il 6 catalog no d6050b elisa kits - by Bioz Stars, 2026-06
    96/100 stars

    Images

    1) Product Images from "The Relationship Between Decreased Serum Klotho Protein and Cognitive Impairment in Patients After Abdominal Surgery"

    Article Title: The Relationship Between Decreased Serum Klotho Protein and Cognitive Impairment in Patients After Abdominal Surgery

    Journal: Journal of Inflammation Research

    doi: 10.2147/JIR.S593405

    The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) postoperative IL-6 in all 93 cases of patients after abdominal surgery.
    Figure Legend Snippet: The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) postoperative IL-6 in all 93 cases of patients after abdominal surgery.

    Techniques Used:

    Proposed mechanism linking decreased postoperative serum Klotho levels to postoperative cognitive dysfunction (POCD) after abdominal surgery. Surgery and prolonged anesthesia lead to a reduction in serum Klotho levels, which contributes to increased oxidative stress and systemic inflammation, as indicated by elevated levels of CRP, IL-1β, and IL-6. These processes promote neuroinflammation and synaptic dysfunction, resulting in cognitive decline and POCD. Arrows indicate the direction of the effects, illustrating how decreased Klotho mediates the relationship between perioperative stress, inflammation, and postoperative cognitive impairment.
    Figure Legend Snippet: Proposed mechanism linking decreased postoperative serum Klotho levels to postoperative cognitive dysfunction (POCD) after abdominal surgery. Surgery and prolonged anesthesia lead to a reduction in serum Klotho levels, which contributes to increased oxidative stress and systemic inflammation, as indicated by elevated levels of CRP, IL-1β, and IL-6. These processes promote neuroinflammation and synaptic dysfunction, resulting in cognitive decline and POCD. Arrows indicate the direction of the effects, illustrating how decreased Klotho mediates the relationship between perioperative stress, inflammation, and postoperative cognitive impairment.

    Techniques Used:



    Similar Products

    human il-6 quantikine elisa kit  (Bio-Techne corporation)
    97
    Bio-Techne corporation human il-6 quantikine elisa kit
    Human Il 6 Quantikine Elisa Kit, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human il-6 quantikine elisa kit/product/Bio-Techne corporation
    Average 97 stars, based on 1 article reviews
    human il-6 quantikine elisa kit - by Bioz Stars, 2026-06
    97/100 stars
    		  Buy from Supplier
    il 6 catalog no d6050b elisa kits  (R&D Systems)
    96
    R&D Systems il 6 catalog no d6050b elisa kits
    The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) <t>postoperative</t> <t>IL-6</t> in all 93 cases of patients after abdominal surgery.
    Il 6 Catalog No D6050b Elisa Kits, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 6 catalog no d6050b elisa kits/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    il 6 catalog no d6050b elisa kits - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    human il 6 quantikine elisa kit  (R&D Systems)
    96
    R&D Systems human il 6 quantikine elisa kit
    A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 <t>(IL-6)</t> levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).
    Human Il 6 Quantikine Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human il 6 quantikine elisa kit/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    human il 6 quantikine elisa kit - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    d6050b  (R&D Systems)
    96
    R&D Systems d6050b
    A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 <t>(IL-6)</t> levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).
    D6050b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/d6050b/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    d6050b - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    d6050b il 6  (R&D Systems)
    96
    R&D Systems d6050b il 6
    A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 <t>(IL-6)</t> levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).
    D6050b Il 6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/d6050b il 6/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    d6050b il 6 - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    il 6  (R&D Systems)
    96
    R&D Systems il 6
    A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 <t>(IL-6)</t> levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).
    Il 6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 6/product/R&D Systems
    Average 96 stars, based on 1 article reviews
    il 6 - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) postoperative IL-6 in all 93 cases of patients after abdominal surgery.

    Journal: Journal of Inflammation Research

    Article Title: The Relationship Between Decreased Serum Klotho Protein and Cognitive Impairment in Patients After Abdominal Surgery

    doi: 10.2147/JIR.S593405

    Figure Lengend Snippet: The correlation between serum Klotho and clinical indicators. Pearson correlation test was performed between Klotho with ( A ) duration of anesthesia, ( B ) postoperative MoCA scores, ( C ) postoperative CRP, ( D ) postoperative IL-1β, and ( E ) postoperative IL-6 in all 93 cases of patients after abdominal surgery.

    Article Snippet: CRP (catalog no. SEKH-0138) and Klotho (catalog no. SEKH-0280) ELISA kits were purchased from Solarbio (Beijing, China), while IL-1β (catalog no. DLB50) and IL-6 (catalog no. D6050B) ELISA kits were obtained from R&D Systems (Minneapolis).

    Techniques:

    Proposed mechanism linking decreased postoperative serum Klotho levels to postoperative cognitive dysfunction (POCD) after abdominal surgery. Surgery and prolonged anesthesia lead to a reduction in serum Klotho levels, which contributes to increased oxidative stress and systemic inflammation, as indicated by elevated levels of CRP, IL-1β, and IL-6. These processes promote neuroinflammation and synaptic dysfunction, resulting in cognitive decline and POCD. Arrows indicate the direction of the effects, illustrating how decreased Klotho mediates the relationship between perioperative stress, inflammation, and postoperative cognitive impairment.

    Journal: Journal of Inflammation Research

    Article Title: The Relationship Between Decreased Serum Klotho Protein and Cognitive Impairment in Patients After Abdominal Surgery

    doi: 10.2147/JIR.S593405

    Figure Lengend Snippet: Proposed mechanism linking decreased postoperative serum Klotho levels to postoperative cognitive dysfunction (POCD) after abdominal surgery. Surgery and prolonged anesthesia lead to a reduction in serum Klotho levels, which contributes to increased oxidative stress and systemic inflammation, as indicated by elevated levels of CRP, IL-1β, and IL-6. These processes promote neuroinflammation and synaptic dysfunction, resulting in cognitive decline and POCD. Arrows indicate the direction of the effects, illustrating how decreased Klotho mediates the relationship between perioperative stress, inflammation, and postoperative cognitive impairment.

    Article Snippet: CRP (catalog no. SEKH-0138) and Klotho (catalog no. SEKH-0280) ELISA kits were purchased from Solarbio (Beijing, China), while IL-1β (catalog no. DLB50) and IL-6 (catalog no. D6050B) ELISA kits were obtained from R&D Systems (Minneapolis).

    Techniques:

    A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 (IL-6) levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).

    Journal: Communications Medicine

    Article Title: Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene

    doi: 10.1038/s43856-026-01503-y

    Figure Lengend Snippet: A HUVECs were cultured for 4 h in the presence or absence of 500 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin. Cell viability was measured using Cell Counting Kit-8 and expressed relative to the control. B HUVECs were cultured in the presence or absence of 500 ng/ml α-toxin and 50 µM micafungin or caspofungin, and a LDH leakage assay was performed using Cytotoxicity LDH Assay Kit-WST according to the manufacturer’s protocol. LDH release was expressed relative to the control. C HUVECs were cultured for 24 h in the presence or absence of 10 ng/ml α-toxin, 10 µg/ml peptidoglycan (PGN), and the indicated concentrations of micafungin or caspofungin. Interleukin-6 (IL-6) levels in the culture medium were measured using a human IL-6 Quantikine ELISA kit according to the manufacturer’s protocol. D Bone marrow cells were cultured for 3 h in the presence or absence of 100 ng/ml α-toxin and the indicated concentrations of micafungin or caspofungin, and the cells were labeled with antibodies diluted in PBS containing 2% FBS after blocking Fc-receptors with purified rat anti-mouse CD16/CD32. To quantify the amount of CD11b, a flow cytometry analysis was performed using Guava easyCyte. The mean fluorescence intensities of CD11b in Gr-1 + cells are shown. E C57BL/6J mice were injected intraperitoneally with 600 ng of α-toxin and 300 µg of micafungin or caspofungin, which had been pre-mixed and diluted in PBS. The survival of mice was monitored, and Kaplan–Meier survival curves are shown. The total number of mice used in the experiments was 63. Median survival (hours): Control, 6; caspofungin, not reached; micafungin, 6. A one-way ANOVA ( A – D ) or the Log-rank test ( E ) was employed to assess significance. Values are the mean ± standard deviation for panels ( A – D ) ( n = 3).

    Article Snippet: After the treatment of cells with α-toxin, peptidoglycan (PGN), and the test compounds, culture supernatants were harvested and interleukin-6 levels were measured using a human IL-6 Quantikine ELISA kit (R&D Systems, MN, USA).

    Techniques: Cell Culture, Cell Counting, Control, Lactate Dehydrogenase Assay, Enzyme-linked Immunosorbent Assay, Labeling, Blocking Assay, Purification, Flow Cytometry, Fluorescence, Injection, Standard Deviation