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cpass svnt “wild type” kit  (GenScript corporation)

 
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    GenScript corporation cpass svnt “wild type” kit
    Cpass Svnt “Wild Type” Kit, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cpass+svnt+kit/cpass+svnt+kit/pm40288233-74-9-9
    Average 90 stars, based on 1 article reviews
    cpass svnt “wild type” kit - by Bioz Stars, 2026-09
    90/100 stars

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    Activity Assay:

    Article Title: Anti-SARS-CoV-2 inactivated vaccine in patients with ANCA-associated vasculitis: Immunogenicity, safety, antibody decay and the booster dose.
    Article Snippet: SC, Seroconversion defined as a positive serology (IgG titer ≥15 AU/mL) for antiSARS-CoV-2 S1/S2 IgG antibodies after vaccination (Indirect ELISA, LIAISON® SARS-CoV-2 S1/S2 IgG, DiaSorin, Italy). .. Positivity for Nabs defined as a neutralizing activity ≥ 30% (cPass sVNT Kit, GenScript, Piscataway). ..

    Article Title: Immunogenicity decay and case incidence six months post Sinovac-CoronaVac vaccine in autoimmune rheumatic diseases patients.
    Article Snippet: Adjusted analyses included the factorswithp >0.20 at unadjusted analyses, depicted in Table 3, using multiple logistic regression models.SP—seropositivity (IgG titer ≥ 15AU/ml) for anti-SARSCoV-2 S1/S2 IgG antibodies after vaccination (Indirect ELISA, LIAISON® SARS-CoV-2 S1/S2 IgG, DiaSorin, Italy). .. Positivity for NAb was defined as a neutralizing activity ≥30% (cPass sVNT Kit, GenScript, Piscataway, USA). ..

    Inhibition:

    Article Title: Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays
    Article Snippet: .. To detect neutralizing antibodies using an immunoassay method, the cPass sVNT kit (GenScript, Piscataway, NJ, USA) was used. sVNT measures the inhibition of interactions between the horseradish peroxidase (HRP)-conjugated SARS-CoV-2 spike protein receptor-binding domain (RBD) and the extracellular domain of the human angiotensin-converting enzyme 2 (hACE2) receptor ( ). ..

    Article Title: Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays
    Article Snippet: Up to a two-fold dilution was performed for the Abbott AdviseDx SARS-CoV2 IgG II Quant assay, which uses the CMIA method; up to 50-fold dilution was carried out for the Roche Elecsys Anti-SARS-CoV-2 S assay, which uses the ECLIA method due to its narrow measurement range with early saturation. .. For the GenScript cPass sVNT kit, dilution was not conducted because the method represents the result of the inhibition ratio calculated from the optical density measured, which does not necessarily linearly correlate with the titer of the antibodies. .. Although GenScript cPass sVNT kit exhibited a lower Pearson’s correlation coefficient than the Abbott AdviseDx SARS-CoV-2 IgG II, this may be due to the narrower reportable range of GenScript cPass sVNT, leading to early saturation in subjects with high antibody titers.

    Neutralization:

    Article Title: Evaluation of a biotin-based surrogate virus neutralization test for detecting postvaccination antibodies against SARS-CoV-2 variants in sera.
    Article Snippet: .. The neutralizing antibodies of serum from 535 participants (median age 42 years, a short period: median 27 [22 to 32] days after pre boost or after a boost; after a long term period: more than median 141.5 [97 to 168] days after pre boost or after a boost) were measured against the wild type (wild type), B.1.1.7 (Alpha), B.1.351 (Beta), P.1 test. (A) cPass sVNT kit (Genscript Biotech) and (B) a biotin-based sVNT (in this study). bited by neutralization antibodies via HRP-conjugated streptavidin. (Gamma), B.1.617.2 (Delta), and Omicron BA.2 using biotin based sVNT. .. Statistical analyses were performed using GraphPad Prism 8 (GraphPad Software, San Diego, CA, USA).

    Article Title: Evaluation of a biotin-based surrogate virus neutralization test for detecting postvaccination antibodies against SARS-CoV-2 variants in sera
    Article Snippet: In addition, by adjusting the amount of RBD, various neutralization activities at high and low levels could be measured. .. Graphical illustration of the principle of a surrogate SARS-CoV-2 virus neutralization test. (A) cPass sVNT kit (Genscript Biotech) and (B) a biotin-based sVNT (in this study). .. Biotin-based sVNTs use biotinylated RBD for the detection of h ACE2 that has not been inhibited by neutralization antibodies via HRP-conjugated streptavidin.

    other:

    Article Title: Evaluation of a biotin-based surrogate virus neutralization test for detecting postvaccination antibodies against SARS-CoV-2 variants in sera
    Article Snippet: To make up for these shortcomings, alternative methods, such as ELISA based surrogate virus neutralization tests (sVNTs), which can be conducted within 2–3 h, have been widely developed and used at biosafety level 2 without using live viruses directly [ ]. cPass (Genscript Biotech Corp, Piscataway, NJ, USA) is the first FDA approved sVNT kit for detecting neutralizing antibodies that inhibit human angiotensin converting enzyme 2 ( h ACE2) receptor binding domain (RBD) interaction [ ].

    Indirect ELISA:

    Article Title: Growing attention of immunogenicity among patients with autoimmune diseases post-SARS-CoV-2 vaccination: meta-analysis and systematic reviews of the current studies
    Article Snippet: Pasoto et al. , 2022 , HCQ, n = 31; prednisone, n = 14; AZA, n = 11; MMF, n = 7; MTX, n = 4; LEF, n = 1; ABA, n = 1, Ustekinumab, n = 1. , Primary SjS, n = 51. , Sinovac-CoronaVac , 1 & 2 , Indirect ELISA, SARS-CoV-2 sVNT Kit. .. Sampaio-Barros et al. , 2021 , HCQ, n = 3; Prednisone, n = 6; Immunosuppressive, n = 37; Monotherapy, n = 33; MMF, n = 27; MTX, n = 5; AZA, n = 4; LEF, n = 2; RTX, n = 1. , Diffuse SSc, n = 35; Limited SSc, n = 16 , Sinovac-CoronaVac , 2 , Indirect ELISA, cPass sVNT Kit, GenScript. ..

    Virus:

    Article Title: Evaluation of a biotin-based surrogate virus neutralization test for detecting postvaccination antibodies against SARS-CoV-2 variants in sera
    Article Snippet: In addition, by adjusting the amount of RBD, various neutralization activities at high and low levels could be measured. .. Graphical illustration of the principle of a surrogate SARS-CoV-2 virus neutralization test. (A) cPass sVNT kit (Genscript Biotech) and (B) a biotin-based sVNT (in this study). .. Biotin-based sVNTs use biotinylated RBD for the detection of h ACE2 that has not been inhibited by neutralization antibodies via HRP-conjugated streptavidin.



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    Image Search Results


    Antibody titers from the first and second blood samples by the participants’ demographics.

    Journal: Vaccines

    Article Title: The Humoral Immune Response Against COVID-19 Through Vaccination in Hemodialysis Patients

    doi: 10.3390/vaccines13020170

    Figure Lengend Snippet: Antibody titers from the first and second blood samples by the participants’ demographics.

    Article Snippet: NAb was measured using the GenScript SARS-CoV-2 cPASS surrogate virus neutralization test (sVNT) kit (Genscript Biotech Corporation, Piscataway, NJ, USA) and spike-specific immunoglobulin G (IgG) was measured with the Euroimmun anti-SARS-CoV-2 IgG enzyme-linked immunosorbent assay (ELISA) (Euroimmun, Lübeck, Germany).

    Techniques: Infection, Sampling

    Locally estimated scatterplot smoothing curve based on data from the first blood sample collection, illustrating the relationship of antibody levels as follows: ( A – C ) inhibition rates (%) for the surrogate virus neutralization test (sVNT) against the wild-type (WT) strain, ( D – F ) inhibition rates (%) against the Omicron variant, and ( G – I ) IgG levels. The curves are plotted against the number of days since COVID-19 infection ( A , D , G ), the last vaccination ( B , E , H ), and the last exposure to COVID-19 ( C , F , I ). The blue line represents the regression line, and the shaded gray area indicates the 95% confidence interval.

    Journal: Vaccines

    Article Title: The Humoral Immune Response Against COVID-19 Through Vaccination in Hemodialysis Patients

    doi: 10.3390/vaccines13020170

    Figure Lengend Snippet: Locally estimated scatterplot smoothing curve based on data from the first blood sample collection, illustrating the relationship of antibody levels as follows: ( A – C ) inhibition rates (%) for the surrogate virus neutralization test (sVNT) against the wild-type (WT) strain, ( D – F ) inhibition rates (%) against the Omicron variant, and ( G – I ) IgG levels. The curves are plotted against the number of days since COVID-19 infection ( A , D , G ), the last vaccination ( B , E , H ), and the last exposure to COVID-19 ( C , F , I ). The blue line represents the regression line, and the shaded gray area indicates the 95% confidence interval.

    Article Snippet: NAb was measured using the GenScript SARS-CoV-2 cPASS surrogate virus neutralization test (sVNT) kit (Genscript Biotech Corporation, Piscataway, NJ, USA) and spike-specific immunoglobulin G (IgG) was measured with the Euroimmun anti-SARS-CoV-2 IgG enzyme-linked immunosorbent assay (ELISA) (Euroimmun, Lübeck, Germany).

    Techniques: Inhibition, Virus, Neutralization, Variant Assay, Infection

    Locally estimated scatterplot smoothing curve based on data from the second blood sample collection, illustrating the relationship of antibody levels as follows: ( A – C ) inhibition rates (%) for the surrogate virus neutralization test (sVNT) against the wild-type (WT) strain, ( D – F ) inhibition rates (%) against the Omicron variant, and ( G – I ) IgG levels. The curves are plotted against the number of days since COVID-19 infection ( A , D , G ), the last vaccination ( B , E , H ), and the last exposure to COVID-19 ( C , F , I ). The blue line represents the regression line, and the shaded gray area indicates the 95% confidence interval.

    Journal: Vaccines

    Article Title: The Humoral Immune Response Against COVID-19 Through Vaccination in Hemodialysis Patients

    doi: 10.3390/vaccines13020170

    Figure Lengend Snippet: Locally estimated scatterplot smoothing curve based on data from the second blood sample collection, illustrating the relationship of antibody levels as follows: ( A – C ) inhibition rates (%) for the surrogate virus neutralization test (sVNT) against the wild-type (WT) strain, ( D – F ) inhibition rates (%) against the Omicron variant, and ( G – I ) IgG levels. The curves are plotted against the number of days since COVID-19 infection ( A , D , G ), the last vaccination ( B , E , H ), and the last exposure to COVID-19 ( C , F , I ). The blue line represents the regression line, and the shaded gray area indicates the 95% confidence interval.

    Article Snippet: NAb was measured using the GenScript SARS-CoV-2 cPASS surrogate virus neutralization test (sVNT) kit (Genscript Biotech Corporation, Piscataway, NJ, USA) and spike-specific immunoglobulin G (IgG) was measured with the Euroimmun anti-SARS-CoV-2 IgG enzyme-linked immunosorbent assay (ELISA) (Euroimmun, Lübeck, Germany).

    Techniques: Inhibition, Virus, Neutralization, Variant Assay, Infection