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Biacore 3000 spr biosensor instrument
3000 Spr Biosensor Instrument, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/biosensor-spr/3000+biacore+instrument/us12624124-815-19-18
Average 86 stars, based on 1 article reviews
3000 spr biosensor instrument - by Bioz Stars, 2026-11
86/100 stars

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Article Title: Cooperative dimerization of a heterocyclic diamidine determines sequence-specific DNA recognition.
Article Snippet: In the course of a program aimed at discovering novel DNA-targeted antiparasitic drugs, the phenylfuran-benzimidazole unfused aromatic dication DB293 was identified as the first diamidine capable of forming stacked dimers in the DNA minor groove of GC-containing sequences.. Its preferred binding sequence encompasses the tetranucleotide 5′-ATGA‚5′-TCAT to which DB293 binds tightly with a strong positive cooperativity.. Here we have investigated the influence of the DNA sequence on drug binding using two complementary technical approaches: surface plasmon resonance and DNase I footprinting.

Article Title: Promoter scanning of the Human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with ?-alanine
Article Snippet: Competition Fluorescence Binding Assay Aliquots of unlabeled DNA hairpin PA were added to a solution of fluorescent DNA-PA complex at a concentration 10-fold above the K d . The resulting data were normalized and fit to a mathematical model describing both the labeled PA-DNA equilibrium (known K d ) and the unlabeled PA-DNA equilibrium (unknown K d ) using Scientist software (MicroMath, St. Louis, MO) as previously described [ 27 ].



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A schematic representation of an <t>SPR</t> DNA <t>origami</t> <t>biosensor</t> setup. A gold film has a light source directed at it through a glass prism. This generates the surface plasmons in the form of oscillating plasmon waves due to the free plasmons in the metal. The presence of DNA origami with the analytes that are immobilised onto the gold surface at precise and controlled positions shifts the angle of the reflected light, leading to the most optimal SPR signal to be monitored with a detector. Created with BioRender.com.
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A schematic representation of an SPR DNA origami biosensor setup. A gold film has a light source directed at it through a glass prism. This generates the surface plasmons in the form of oscillating plasmon waves due to the free plasmons in the metal. The presence of DNA origami with the analytes that are immobilised onto the gold surface at precise and controlled positions shifts the angle of the reflected light, leading to the most optimal SPR signal to be monitored with a detector. Created with BioRender.com.

Journal: Biosensors

Article Title: DNA Origami and Their Application in Biosensors

doi: 10.3390/bios16050247

Figure Lengend Snippet: A schematic representation of an SPR DNA origami biosensor setup. A gold film has a light source directed at it through a glass prism. This generates the surface plasmons in the form of oscillating plasmon waves due to the free plasmons in the metal. The presence of DNA origami with the analytes that are immobilised onto the gold surface at precise and controlled positions shifts the angle of the reflected light, leading to the most optimal SPR signal to be monitored with a detector. Created with BioRender.com.

Article Snippet: 1990 , The first commercial SPR biosensor , This was created by a company known as Pharmacia Biacore, which determined molecules’ characteristics through affinity and kinetics [ ]. .

Techniques: