az11645373 (Tocris)
Tocris is a verified supplier 
Tocris manufactures this product 
92
Structured Review
Tocris
az11645373
Az11645373, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 34 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/az+11645373/AZ+11645373/pm39225832-59-0-4
Average 92 stars, based on 34 article reviews
Az11645373, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 34 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/az+11645373/AZ+11645373/pm39225832-59-0-4
Average 92 stars, based on 34 article reviews
az11645373 - by Bioz Stars,
2026-10
92/100 stars
Images
Related Articles
other:Article Title: Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD. Article Snippet: 343 344 Treament of pHBECs with P2X7 antagonist: Confluent pHBECs were pre-incubated with AZ 345 11645373, a highly specific Article Title: Lipopolysaccharide-Mediated Induction of Concurrent IL-1β and IL-23 Expression in THP-1 Cells Exhibits Differential Requirements for Caspase-1 and Cathepsin B Activity. Article Snippet: The inflammasome is a multimeric protein complex required for interleukin (IL)-1b production.. Upon lipopolysaccharide (LPS) triggering of toll-like receptor (TLR)-4 and subsequent ATP signaling, the NOD-like receptor containing-pyrin domain 3 (NLRP3) inflammasome is activated to cleave pro-caspase-1 into caspase-1, allowing the secretion of IL-1b.. IL-1b is known to function with IL-23 in the regulation of IL-17-producing CD4 T cells, Th17 cells, in adaptive immunity. Article Title: Method for treatment of macular degeneration by modulating P2Y12 or P2X7 receptors Article Snippet: Other known compositions that are also useful to inhibit the P2X7 receptors (antagonists for the P2X7 receptor), e.g., A740003 (18/40 nM), AZ-10606120 (19/1.4 nM), AZ-11645373 (6 nM human), KN-62 (15 nM human), A-839977, A-74003, NF279, Article Title: Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD. Article Snippet: AZ 11645373) came from Article Title: P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts. Article Snippet: P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts Ankita Agrawal, Zanne Henriksen, Susanne Syberg, Solveig Petersen, Derya Aslan, Marie Solgaard, Nis Nissen, Tommy Korsgaard Larsen, Peter Schwarz, Thomas H. Steinberg, Niklas Rye Jørgensen PII: S8756-3282(16)30344-1 DOI: doi: 10.1016/j.bone.2016.11.011 Reference: BON 11183 To appear in: Bone Received date: 8 August 2016 Revised date: 10 November 2016 Accepted date: 11 November 2016 Please cite this article as: Agrawal Ankita, Henriksen Zanne, Syberg Susanne, Petersen Solveig, Aslan Derya, Solgaard Marie, Nissen Nis, Larsen Tommy Korsgaard, Schwarz Peter, Steinberg Thomas H., Jørgensen Niklas Rye, P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts, Bone (2016), doi: 10.1016/j.bone.2016.11.011 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Article Title: Activated Human CD4+CD45RO+ Memory T-Cells Indirectly Inhibit NLRP3 Inflammasome Activation through Downregulation of P2X7R Signalling Article Snippet: recFASL and ATP were purchased from SIGMA-Aldrich. |
