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ad-shctrl  (Genechem)

 
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    Structured Review

    Genechem ad-shctrl
    Knockdown of Steap4 in cardiomyocytes partially rescued the fatal heart failure in TG mice. (A) Cumulative survival rates of TG mice in <t>shCtrl</t> group (n = 20) and sh Steap4 (n = 20) group were recorded. (B) Representative images of the heart. (C) <t>Cardiac</t> <t>Slc40a1</t> , Steap4 , and Fth proteins were measured using western blot analysis, normalized to β-actin (n = 4). (D) Total iron levels in the heart and serum were measured (n = 4). (E) Long-axis M-mode echocardiogram images and its analysis (n = 8). (F) Cardiac Nppa , Nppb , Myh7 mRNA were measured using qPCR, normalized to β-actin (n = 4). (G) Masson trichrome staining images and quantification of fibrotic areas (n = 4). The data is presented as the mean value plus or minus the standard error of the mean. Statistical significance is denoted by *p < 0.05 and **p < 0.01.
    Ad Shctrl, supplied by Genechem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ad-shctrl/product/Genechem
    Average 90 stars, based on 1 article reviews
    ad-shctrl - by Bioz Stars, 2026-06
    90/100 stars

    Images

    1) Product Images from "Elevated SLC40A1 impairs cardiac function and exacerbates mitochondrial dysfunction, oxidative stress, and apoptosis in ischemic myocardia"

    Article Title: Elevated SLC40A1 impairs cardiac function and exacerbates mitochondrial dysfunction, oxidative stress, and apoptosis in ischemic myocardia

    Journal: International Journal of Biological Sciences

    doi: 10.7150/ijbs.89368

    Knockdown of Steap4 in cardiomyocytes partially rescued the fatal heart failure in TG mice. (A) Cumulative survival rates of TG mice in shCtrl group (n = 20) and sh Steap4 (n = 20) group were recorded. (B) Representative images of the heart. (C) Cardiac Slc40a1 , Steap4 , and Fth proteins were measured using western blot analysis, normalized to β-actin (n = 4). (D) Total iron levels in the heart and serum were measured (n = 4). (E) Long-axis M-mode echocardiogram images and its analysis (n = 8). (F) Cardiac Nppa , Nppb , Myh7 mRNA were measured using qPCR, normalized to β-actin (n = 4). (G) Masson trichrome staining images and quantification of fibrotic areas (n = 4). The data is presented as the mean value plus or minus the standard error of the mean. Statistical significance is denoted by *p < 0.05 and **p < 0.01.
    Figure Legend Snippet: Knockdown of Steap4 in cardiomyocytes partially rescued the fatal heart failure in TG mice. (A) Cumulative survival rates of TG mice in shCtrl group (n = 20) and sh Steap4 (n = 20) group were recorded. (B) Representative images of the heart. (C) Cardiac Slc40a1 , Steap4 , and Fth proteins were measured using western blot analysis, normalized to β-actin (n = 4). (D) Total iron levels in the heart and serum were measured (n = 4). (E) Long-axis M-mode echocardiogram images and its analysis (n = 8). (F) Cardiac Nppa , Nppb , Myh7 mRNA were measured using qPCR, normalized to β-actin (n = 4). (G) Masson trichrome staining images and quantification of fibrotic areas (n = 4). The data is presented as the mean value plus or minus the standard error of the mean. Statistical significance is denoted by *p < 0.05 and **p < 0.01.

    Techniques Used: Western Blot, Staining



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    Image Search Results


    Knockdown of Steap4 in cardiomyocytes partially rescued the fatal heart failure in TG mice. (A) Cumulative survival rates of TG mice in shCtrl group (n = 20) and sh Steap4 (n = 20) group were recorded. (B) Representative images of the heart. (C) Cardiac Slc40a1 , Steap4 , and Fth proteins were measured using western blot analysis, normalized to β-actin (n = 4). (D) Total iron levels in the heart and serum were measured (n = 4). (E) Long-axis M-mode echocardiogram images and its analysis (n = 8). (F) Cardiac Nppa , Nppb , Myh7 mRNA were measured using qPCR, normalized to β-actin (n = 4). (G) Masson trichrome staining images and quantification of fibrotic areas (n = 4). The data is presented as the mean value plus or minus the standard error of the mean. Statistical significance is denoted by *p < 0.05 and **p < 0.01.

    Journal: International Journal of Biological Sciences

    Article Title: Elevated SLC40A1 impairs cardiac function and exacerbates mitochondrial dysfunction, oxidative stress, and apoptosis in ischemic myocardia

    doi: 10.7150/ijbs.89368

    Figure Lengend Snippet: Knockdown of Steap4 in cardiomyocytes partially rescued the fatal heart failure in TG mice. (A) Cumulative survival rates of TG mice in shCtrl group (n = 20) and sh Steap4 (n = 20) group were recorded. (B) Representative images of the heart. (C) Cardiac Slc40a1 , Steap4 , and Fth proteins were measured using western blot analysis, normalized to β-actin (n = 4). (D) Total iron levels in the heart and serum were measured (n = 4). (E) Long-axis M-mode echocardiogram images and its analysis (n = 8). (F) Cardiac Nppa , Nppb , Myh7 mRNA were measured using qPCR, normalized to β-actin (n = 4). (G) Masson trichrome staining images and quantification of fibrotic areas (n = 4). The data is presented as the mean value plus or minus the standard error of the mean. Statistical significance is denoted by *p < 0.05 and **p < 0.01.

    Article Snippet: Ad-sh Slc40a1 and Ad-shCtrl were provided by GeneChem Technology (Shanghai, China), in the form of adenoviral vectors carrying shRNA- Slc40a1 .Protein expression was observed 48 hours after viral infection.

    Techniques: Western Blot, Staining