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human methylation 450k bead-chip microarray  (INFINIUM Inc)

 
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    INFINIUM Inc human methylation 450k bead-chip microarray
    Human Methylation 450k Bead Chip Microarray, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/450k+microarray+chips/infinium+humanmethylation450+beadchip/bio_rxiv__422345-179-30-29
    Average 90 stars, based on 1 article reviews
    human methylation 450k bead-chip microarray - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Microarray:

    Article Title: H1‐0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia
    Article Snippet: .. Hence, we analyzed previously published 450K Infinium microarray DNA methylation data comprising patient samples of T‐ALL and six B‐ALL subtypes ( n = 546). .. Indeed, the mean CGI shore methylation of H1‐0 , comprising probes cg07141002 and cg01883777, inversely correlated with H1‐0 expression (Pearson r = −0.645, p < 0.0001; Figures and ) and was lowest in ETV6::RUNX1 + BCP‐ALL (Figure ), indicating that H1‐0 expression is regulated via dynamic methylation of its CGI shore in leukemia.

    Article Title: DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights
    Article Snippet: .. Microarray DNA methylation data (Infinium Human Methylation 450k BeadChip) were analyzed and associated with functional/regulatory genome annotation data, transcriptional profiles and clinico-biological parameters. ..

    DNA Methylation Assay:

    Article Title: H1‐0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia
    Article Snippet: .. Hence, we analyzed previously published 450K Infinium microarray DNA methylation data comprising patient samples of T‐ALL and six B‐ALL subtypes ( n = 546). .. Indeed, the mean CGI shore methylation of H1‐0 , comprising probes cg07141002 and cg01883777, inversely correlated with H1‐0 expression (Pearson r = −0.645, p < 0.0001; Figures and ) and was lowest in ETV6::RUNX1 + BCP‐ALL (Figure ), indicating that H1‐0 expression is regulated via dynamic methylation of its CGI shore in leukemia.

    Article Title: DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights
    Article Snippet: .. Microarray DNA methylation data (Infinium Human Methylation 450k BeadChip) were analyzed and associated with functional/regulatory genome annotation data, transcriptional profiles and clinico-biological parameters. ..

    Article Title: PINCAGE: probabilistic integration of cancer genomics data for perturbed gene identification and sample classification.
    Article Snippet: .. BRCA samples with both 450k Infinium array DNA methylation and RNA-seq expression data were downloaded from TCGA consortium Data Portal (Fig. 1A). ..

    Article Title: Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain
    Article Snippet: .. DNA Methylation Analysis Infinium HumanMethylation 450k BeadChip Array DNA was purified from human brain samples or fluorescence-activated nuclear sorting (FANS)-sorted nuclei using the DNeasy Blood & Tissue kit (Qiagen) and bisulfite converted using EZ DNA methylation Gold kit (Zymo Research) according to manufacturers’ instructions. .. Methylation profiling was performed using Infinium HumanMethylation450 BeadChip assay (Illumina) by The SNP&SEQ Technology Platform at Science for Life Laboratory (Sweden).

    Methylation:

    Article Title: DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights
    Article Snippet: .. Microarray DNA methylation data (Infinium Human Methylation 450k BeadChip) were analyzed and associated with functional/regulatory genome annotation data, transcriptional profiles and clinico-biological parameters. ..

    Functional Assay:

    Article Title: DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights
    Article Snippet: .. Microarray DNA methylation data (Infinium Human Methylation 450k BeadChip) were analyzed and associated with functional/regulatory genome annotation data, transcriptional profiles and clinico-biological parameters. ..

    RNA Sequencing:

    Article Title: PINCAGE: probabilistic integration of cancer genomics data for perturbed gene identification and sample classification.
    Article Snippet: .. BRCA samples with both 450k Infinium array DNA methylation and RNA-seq expression data were downloaded from TCGA consortium Data Portal (Fig. 1A). ..

    Expressing:

    Article Title: PINCAGE: probabilistic integration of cancer genomics data for perturbed gene identification and sample classification.
    Article Snippet: .. BRCA samples with both 450k Infinium array DNA methylation and RNA-seq expression data were downloaded from TCGA consortium Data Portal (Fig. 1A). ..

    Purification:

    Article Title: Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain
    Article Snippet: .. DNA Methylation Analysis Infinium HumanMethylation 450k BeadChip Array DNA was purified from human brain samples or fluorescence-activated nuclear sorting (FANS)-sorted nuclei using the DNeasy Blood & Tissue kit (Qiagen) and bisulfite converted using EZ DNA methylation Gold kit (Zymo Research) according to manufacturers’ instructions. .. Methylation profiling was performed using Infinium HumanMethylation450 BeadChip assay (Illumina) by The SNP&SEQ Technology Platform at Science for Life Laboratory (Sweden).

    Fluorescence:

    Article Title: Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain
    Article Snippet: .. DNA Methylation Analysis Infinium HumanMethylation 450k BeadChip Array DNA was purified from human brain samples or fluorescence-activated nuclear sorting (FANS)-sorted nuclei using the DNeasy Blood & Tissue kit (Qiagen) and bisulfite converted using EZ DNA methylation Gold kit (Zymo Research) according to manufacturers’ instructions. .. Methylation profiling was performed using Infinium HumanMethylation450 BeadChip assay (Illumina) by The SNP&SEQ Technology Platform at Science for Life Laboratory (Sweden).



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    Image Search Results


    Weight loss driven improvement of methylation age.

    Journal: Frontiers in Endocrinology

    Article Title: Implication of DNA methylation during lifestyle mediated weight loss

    doi: 10.3389/fendo.2023.1181002

    Figure Lengend Snippet: Weight loss driven improvement of methylation age.

    Article Snippet: hypocaloric dietary intervention/ 6 weeks Aim: investigate the effects of short-term hypocaloric diet-induced weight loss on DNA methylation profile in leukocytes from women with severe obesity , 11 women with morbid obesity (Age = 36.9 ± 10.3 years; BMI: 58.5 ± 10.5 kg/m 2 ) , Illumina HumanMethylation 450K Bead Chips microarray Tissue: blood , intervention changed the methylation levels at 16,064 CpG sites; These CpGs sites were related to cancer, cell cycle-related, MAPK, Rap1, and Ras signaling pathways; regardless of hypocaloric intervention, a group of 878 CpGs (related to 649 genes) remained significantly altered in obese women when compared with normal-weight women; Pathway enrichment analysis identified genes related to the cadherin and Wnt pathway, angiogenesis signaling, and p53 pathways by glucose deprivation , Nicoletti et al. 2020 ( ) .

    Techniques: Methylation, DNA Methylation Assay

    In-utero methylation studies under lifestyle intervention.

    Journal: Frontiers in Endocrinology

    Article Title: Implication of DNA methylation during lifestyle mediated weight loss

    doi: 10.3389/fendo.2023.1181002

    Figure Lengend Snippet: In-utero methylation studies under lifestyle intervention.

    Article Snippet: hypocaloric dietary intervention/ 6 weeks Aim: investigate the effects of short-term hypocaloric diet-induced weight loss on DNA methylation profile in leukocytes from women with severe obesity , 11 women with morbid obesity (Age = 36.9 ± 10.3 years; BMI: 58.5 ± 10.5 kg/m 2 ) , Illumina HumanMethylation 450K Bead Chips microarray Tissue: blood , intervention changed the methylation levels at 16,064 CpG sites; These CpGs sites were related to cancer, cell cycle-related, MAPK, Rap1, and Ras signaling pathways; regardless of hypocaloric intervention, a group of 878 CpGs (related to 649 genes) remained significantly altered in obese women when compared with normal-weight women; Pathway enrichment analysis identified genes related to the cadherin and Wnt pathway, angiogenesis signaling, and p53 pathways by glucose deprivation , Nicoletti et al. 2020 ( ) .

    Techniques: Methylation, DNA Methylation Assay, Activity Assay, Control, Modification