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conventional ythdf1 ko mice  (Cyagen Biosciences)


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    Structured Review

    Cyagen Biosciences conventional ythdf1 ko mice
    Figure 1 <t>YTHDF1</t> deficiency impairs visual function and leads to progressive retinal degeneration
    Conventional Ythdf1 Ko Mice, supplied by Cyagen Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ythdf1/Ythdf1/pm40116022-53-0-12
    Average 93 stars, based on 4 article reviews
    conventional ythdf1 ko mice - by Bioz Stars, 2026-11
    93/100 stars

    Images

    1) Product Images from "Single-cell sequencing analysis reveals the essential role of the m 6 A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation."

    Article Title: Single-cell sequencing analysis reveals the essential role of the m 6 A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation.

    Journal: Zoological research

    doi: 10.24272/j.issn.2095-8137.2024.399

    Figure 1 YTHDF1 deficiency impairs visual function and leads to progressive retinal degeneration
    Figure Legend Snippet: Figure 1 YTHDF1 deficiency impairs visual function and leads to progressive retinal degeneration

    Techniques Used:

    Figure 3 Loss of Ythdf1 impairs visual function and leads to progressive degeneration of rod cells
    Figure Legend Snippet: Figure 3 Loss of Ythdf1 impairs visual function and leads to progressive degeneration of rod cells

    Techniques Used:

    Figure 5 Transcriptome-wide identification of YTHDF1 targets in retinal rod cells
    Figure Legend Snippet: Figure 5 Transcriptome-wide identification of YTHDF1 targets in retinal rod cells

    Techniques Used:

    Figure 6 YTHDF1 promotes translation of m6A-methylated Tulp1 and Dhx38 in retinas
    Figure Legend Snippet: Figure 6 YTHDF1 promotes translation of m6A-methylated Tulp1 and Dhx38 in retinas

    Techniques Used: Methylation

    Related Articles

    Generated:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: The Ythdf1 KO allele was generated using the CRISPR–Cas9 system by Cyagen Biosciences (Guangzhou, China). .. The Ythdf1 KO allele was generated using the CRISPR–Cas9 system by Cyagen Biosciences (Guangzhou, China). ..

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China). .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China).

    CRISPR:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: The Ythdf1 KO allele was generated using the CRISPR–Cas9 system by Cyagen Biosciences (Guangzhou, China). .. The Ythdf1 KO allele was generated using the CRISPR–Cas9 system by Cyagen Biosciences (Guangzhou, China). ..

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China). .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China).

    Quantitative RT-PCR:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: HEK293T ATCC CRL-3216 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025

    shRNA:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: HEK293T ATCC CRL-3216 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025

    Recombinant:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: HEK293T ATCC CRL-3216 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025 .. HCT116 ATCC CCL-247 Ytdhf1 -/- MEF This paper N/A WT MEF This paper N/A Human skin fibroblasts (HSF) Sun et al. 75 N/A YTHDF1 W411A HEK293T This paper N/A Experimental models: Organisms/strains Ythdf1 -/- mice Cyagen company Serial Number: KOCMP-11432-Ythdf1 C57BL/6N Cyagen company N/A Oligonucleotides Gene-specific primers for RT-qPCR in this study This paper see Table S5 shRNA and siRNA sequences used in this study This paper see Table S6 Recombinant DNA FLAG-YTHDF1 This paper N/A FLAG-YTHDF1-Mut This paper N/A FLAG-YTHDF2 This paper N/A FLAG-YTHDF3 This paper N/A (Continued on next page) e3 Molecular Cell 85, 1–17.e1–e8, June 5, 2025

    Mutagenesis:

    Article Title: YTHDF1 differentiates the contributing roles of mTORC1 in aging.
    Article Snippet: .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China). .. Generation of homozygous YTHDF1 W411A mutant HEK293T cell line A homozygous YTHDF1 W411A/W411A mutant HEK293T cell line was generated using the CRISPR/Cas9 system by Cyagen Biosciences (Guangzhou, China).



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