human membrane protein activation library (Addgene inc)
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human membrane protein activation library
Human Membrane Protein Activation Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/wright/Wright+Human+Membrane+Protein+Activation+Library+(Pooled+Library+%23113345)/pm41872506-211-5-14
Average 92 stars, based on 4 article reviews
Human Membrane Protein Activation Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/wright/Wright+Human+Membrane+Protein+Activation+Library+(Pooled+Library+%23113345)/pm41872506-211-5-14
Average 92 stars, based on 4 article reviews
human membrane protein activation library - by Bioz Stars,
2026-11
92/100 stars
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other:Article Title: Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform. Article Snippet: The library DNA was electroporated into NEB 10- beta electrocompetent E. coli [New England Biolabs (NEB), cat. no. C3020K] at 2.0 kV, 200 Omega and 25 μF using a Gene Pulser Xcell Electroporation System (BioRad). Infection:Article Title: Cell softness renders cytotoxic T lymphocytes and T leukemic cells resistant to perforin-mediated killing Article Snippet: Jurkat cells were transduced with a lentiviral vector encoding dCas9-V64-p65-HSF1 and selected with blasticidin. .. 1 × 10 7 cells Jurkat cells were infected with the pooled Membrane:Article Title: Cell softness renders cytotoxic T lymphocytes and T leukemic cells resistant to perforin-mediated killing Article Snippet: Jurkat cells were transduced with a lentiviral vector encoding dCas9-V64-p65-HSF1 and selected with blasticidin. .. 1 × 10 7 cells Jurkat cells were infected with the pooled Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. Article Snippet: .. The Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity Article Snippet: .. The Article Title: Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform Article Snippet: .. The Article Title: TMX2 potentiates cell viability of hepatocellular carcinoma by promoting autophagy and mitophagy. Article Snippet: The dysregulation of membrane protein expression has been implicated in tumorigenesis and progression, including hepatocellular carcinoma (HCC).. In this study, we aimed to identify membrane proteins that modulate HCC viability.. To achieve this, we performed a CRISPR activation screen targeting human genes encoding membrane-associated proteins, revealing TMX2 as a potential driver of HCC cell viability. Article Title: Engineering NK and T cells with metabolite-sensing receptors to target solid tumors. Article Snippet: The customized library consisted of 1,070 sgRNAs targeting 256 genes with four guides per gene and 46 NTCs (Supplementary Table 1c), using protospacer sequences from the Human Genome-Wide CRISPRa-v2 Libraries69 and Human CRISPRa Library19 cloned into pKVL2-U6gRNA_SAM(BbsI)-PGKpuroBFP-W vector (Addgene, 112925) by Genscript. .. The large-scale library was a Transduction:Article Title: Cell softness renders cytotoxic T lymphocytes and T leukemic cells resistant to perforin-mediated killing Article Snippet: Jurkat cells were transduced with a lentiviral vector encoding dCas9-V64-p65-HSF1 and selected with blasticidin. .. 1 × 10 7 cells Jurkat cells were infected with the pooled Activation Assay:Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. Article Snippet: .. The Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity Article Snippet: .. The Article Title: Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform Article Snippet: .. The Article Title: TMX2 potentiates cell viability of hepatocellular carcinoma by promoting autophagy and mitophagy. Article Snippet: The dysregulation of membrane protein expression has been implicated in tumorigenesis and progression, including hepatocellular carcinoma (HCC).. In this study, we aimed to identify membrane proteins that modulate HCC viability.. To achieve this, we performed a CRISPR activation screen targeting human genes encoding membrane-associated proteins, revealing TMX2 as a potential driver of HCC cell viability. Article Title: Engineering NK and T cells with metabolite-sensing receptors to target solid tumors. Article Snippet: The customized library consisted of 1,070 sgRNAs targeting 256 genes with four guides per gene and 46 NTCs (Supplementary Table 1c), using protospacer sequences from the Human Genome-Wide CRISPRa-v2 Libraries69 and Human CRISPRa Library19 cloned into pKVL2-U6gRNA_SAM(BbsI)-PGKpuroBFP-W vector (Addgene, 112925) by Genscript. .. The large-scale library was a Plasmid Preparation:Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. Article Snippet: .. The Article Title: A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity Article Snippet: .. The CRISPR:Article Title: TMX2 potentiates cell viability of hepatocellular carcinoma by promoting autophagy and mitophagy. Article Snippet: The dysregulation of membrane protein expression has been implicated in tumorigenesis and progression, including hepatocellular carcinoma (HCC).. In this study, we aimed to identify membrane proteins that modulate HCC viability.. To achieve this, we performed a CRISPR activation screen targeting human genes encoding membrane-associated proteins, revealing TMX2 as a potential driver of HCC cell viability. |
