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web-based platform  (TriNetX Inc)

 
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    TriNetX Inc web-based platform
    Web Based Platform, supplied by TriNetX Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/web-based+platform/web+based+platform/pm37832859-123-3-0
    Average 90 stars, based on 1 article reviews
    web-based platform - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: Trends, risk factors, and outcomes of selective screening for abdominal aortic aneurysms in at-risk patients.
    Article Snippet: Objectives: For men ages 65 to 75 years without a smoking history and for women ages 65 to 75 years with a smoking history, the United States Preventative Service Task Force recommends that primary care providers (PCPs) use their clinical judgement when offering abdominal aortic aneurysm (AAA) screening.. This study describes the trends in screening for these cohorts, identifies factors that may influence screening rates, and compares outcomes between screened and unscreened patients.. Methods: The TriNetX population database was queried for subjects with routine PCP visit between ages 65 to 75 from 2007 to 2023 to create cohorts of male smokers, male nonsmokers, and female smokers.

    Article Title: From flare to care: Dermatologists' impact on pediatric atopic dermatitis hospital admissions.
    Article Snippet: Correspondence Jill K. Wieser, Case Western Reserve University Department of Dermatology, University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Lakeside Suite 3500 Cleveland, OH 44106, USA.. Email: jill.wieser.2@gmail.com Abstract Background/Objectives: Atopic dermatitis (AD) is a common chronic skin disease in the pediatric population; however, rates of admissions for flares in patients established with dermatology compared to those that are not established have not been fully assessed in prior studies.. Methods: We reviewed electronic medical records of patients hospitalized (billing codes 99221–99223, 99217) with diagnoses encompassing AD, eczema, and dermatitis (ICD-10 codes L20.8-L20.9, L30.8-L30.9) between January 1, 2011, and December 31, 2021, at University Hospitals (UH) in Cleveland, Ohio.

    Article Title: Glucagon-Like Peptide-1 Receptor Agonists are Associated with Improved Survival and Reduced Liver-Related Events in Patients with Type 2 Diabetes and Metabolic Dysfunction-Associated Liver Disease: A Large Real-World Retrospective Study.
    Article Snippet: Please cite this article as: Liu BD, Aly M, Hsin-Ti Lin C, Panesar N, Hill H, Qureshi K, Glucagon-Like Peptide-1 Receptor Agonists are Associated with Improved Survival and Reduced Liver-Related Events in Patients with Type 2 Diabetes and Metabolic Dysfunction-Associated Liver Disease: A Large RealWorld Retrospective Study, Endocrine Practice (2025), doi: https://doi.org/10.1016/j.eprac.2025.04.017.

    Article Title: Trends in the Epidemiology of Deep Vein Thrombosis and Pulmonary Embolism in Patients Undergoing Surgery
    Article Snippet: Global Collaborative Network The Global Collaborative Network through TriNetX is a web-based database tool that allows for research of population cohorts, feasibility queries, and collaboration with medical researchers worldwide.

    Article Title: Association between Semaglutide and Non-Arteritic Anterior Ischemic Optic Neuropathy: A Multinational Population-Based Real-World Study.
    Article Snippet: 58 Objective: To investigate whether semaglutide increases the risk of non-arteritic anterior ischemic 59 optic neuropathy (NAION) in the general population.. 60 Design: This retrospective cohort study utilized a de-identified global electronic medical records 61 database.. The enrollment period was extended from January 2017 to August 2023, with 62 observations concluding in August 2024.

    Article Title: Hyponatremia and the risk of sepsis in the setting of chronic kidney disease not on dialysis
    Article Snippet: The data are searchable via standardized terminologies on TriNetX's web-based platform.

    Article Title: Patients undergoing major amputation for peripheral arterial disease are at high risk for developing major depressive disorder and requiring long-term antidepressants.
    Article Snippet: Objective: Amputation is an undesirable outcome of severe peripheral artery disease (PAD), which affects both the mobility and broader lifestyle of the patient.. Prior studies have shown that lower extremity amputation is associated with increased risk of developing depression in the postoperative period.. However, these studies are primarily single-center studies, confined to specific populations, or do not include analysis over various timepoints.

    Article Title: Nonunion Fractures: Trends in Epidemiology and Treatment of Femur Fractures, 2017-2022
    Article Snippet: Global collaborative network The TriNetX Global Collaborative Network is a Web-based database that facilitates research on population cohorts, feasibility queries, and collaboration with medical researchers worldwide.



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    a , Schematic of the CRISPR–Cas9 knockout strategy targeting slc45a2 , designed to induce a visible pigmentation-loss phenotype for screening. Representative brightfield images of 6 and 21 dpf WT and cr slc45a2 zebrafish show loss of melanin pigmentation in mutants. b , Schematic of CRISPR guide RNA target sites (aa and ab) on the slc45a2 gene with representative Sanger sequencing traces and ICE analysis of indels from 7 dpf larvae injected at the one-cell stage with both guides. c , Indel efficiency rates for each slc45a2 CRISPR target site. d , Schematic of CRISPR guide RNA target sites (aa and ab) on the tgr5 gene with representative Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with tgr5 and slc45a2 guides (latter not shown). e , Indel efficiency rates for each tgr5 CRISPR target site. f , Schematic of the CRISPR target site (ab) on cyp7a1 with corresponding Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with cyp7a1 and slc45a2 guides (latter not shown). g , Indel efficiency rates for the cyp7a1 CRISPR target site. h-k , Biometrics of body length ( h , standard length, SL), muscle width ( i ), liver size ( j ) and adipose tissue size ( k ) in WT cr slc45a2 , WT cr tgr5 and WT cr cyp7a1 zebrafish at 21 dpf. l , Heat map of selected adipogenic, lipolytic, myogenic, proteolytic and inflammatory gene expression profiles in pooled WT, crslc45a2 , crtgr5 and crcyp7a1 zebrafish at 21 dpf, determined by bulk RNA-seq (n = 4 samples of 5 fish per condition). All data are mean ± s.e.m. P values were determined by one-way ANOVA with Tukey’s multiple-comparisons test ( h,i ) and Kruskal–Wallis test with Dunn’s multiple-comparisons post hoc adjustment ( j,k ). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

    Journal: bioRxiv

    Article Title: YAP disrupts bile acid homeostasis to drive cancer-associated cachexia

    doi: 10.64898/2026.02.01.702698

    Figure Lengend Snippet: a , Schematic of the CRISPR–Cas9 knockout strategy targeting slc45a2 , designed to induce a visible pigmentation-loss phenotype for screening. Representative brightfield images of 6 and 21 dpf WT and cr slc45a2 zebrafish show loss of melanin pigmentation in mutants. b , Schematic of CRISPR guide RNA target sites (aa and ab) on the slc45a2 gene with representative Sanger sequencing traces and ICE analysis of indels from 7 dpf larvae injected at the one-cell stage with both guides. c , Indel efficiency rates for each slc45a2 CRISPR target site. d , Schematic of CRISPR guide RNA target sites (aa and ab) on the tgr5 gene with representative Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with tgr5 and slc45a2 guides (latter not shown). e , Indel efficiency rates for each tgr5 CRISPR target site. f , Schematic of the CRISPR target site (ab) on cyp7a1 with corresponding Sanger sequencing traces and ICE analysis from 7 dpf larvae co-injected at the one-cell stage with cyp7a1 and slc45a2 guides (latter not shown). g , Indel efficiency rates for the cyp7a1 CRISPR target site. h-k , Biometrics of body length ( h , standard length, SL), muscle width ( i ), liver size ( j ) and adipose tissue size ( k ) in WT cr slc45a2 , WT cr tgr5 and WT cr cyp7a1 zebrafish at 21 dpf. l , Heat map of selected adipogenic, lipolytic, myogenic, proteolytic and inflammatory gene expression profiles in pooled WT, crslc45a2 , crtgr5 and crcyp7a1 zebrafish at 21 dpf, determined by bulk RNA-seq (n = 4 samples of 5 fish per condition). All data are mean ± s.e.m. P values were determined by one-way ANOVA with Tukey’s multiple-comparisons test ( h,i ) and Kruskal–Wallis test with Dunn’s multiple-comparisons post hoc adjustment ( j,k ). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

    Article Snippet: Indels in the sequenced data were analysed using the Inference of CRISPR Edits (ICE) web-based platform (Synthego).

    Techniques: CRISPR, Knock-Out, Sequencing, Injection, Gene Expression, RNA Sequencing