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cosmx fluorescent probe hybridisation  (Bruker Corporation)


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    Bruker Corporation cosmx fluorescent probe hybridisation
    Cosmx Fluorescent Probe Hybridisation, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/visium+array+slide/MM2/pm39787997-83-191-190
    Average 97 stars, based on 1 article reviews
    cosmx fluorescent probe hybridisation - by Bioz Stars, 2026-10
    97/100 stars

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    Related Articles

    other:

    Article Title: Evaluating chemical and surface stability of thermoformed and 3D-printed clear aligners after intraoral exposure
    Article Snippet: A Bruker Tracer 5i analyzer, equipped with a 20 mm 2 silicon drift detector and a Rhodium (Rh) anode, was employed for this analysis.

    Article Title: Shaping efficiency versus dentin conservation: a micro-CT taper-based analysis
    Article Snippet: Canal configuration was assessed (CTVol v2.3.1; Bruker-microCT), and canal volume (mm3) and surface area (mm2) were quantified using CTAn v1.6.6.0 (Bruker-microCT).

    Article Title: Shaping efficiency versus dentin conservation: a micro-CT taper-based analysis
    Article Snippet: After each enlargement step, quantitative analyses were performed to determine canal volume (mm3), surface area (mm2), the percentage of unprepared canal surface, and the volume of dentin removed (CTAn v1.6.6.0, Bruker-microCT).

    Article Title: Shaping efficiency versus dentin conservation: a micro-CT taper-based analysis.
    Article Snippet: Canal configuration was assessed (CTVol v2.3.1; Bruker-microCT), and canal volume (mm3) and surface area (mm2) were quantified using CTAn v1.6.6.0 (Bruker-microCT).

    Mass Spectrometry:

    Article Title: Proteomic analysis identifies distinct signaling pathways in lumbar intervertebral disc degeneration between type-2 diabetic and non-diabetic patients.
    Article Snippet: Liquid chromatography tandem mass spectometry (LC-MS/MS) Each fraction of peptides was analyzed by LC-MS/MS on a high-resolution Orbitrap Exploris 480 mass spectrometer (Thermo Fisher Scientific). .. Briefly, each fraction of peptides were resuspended in 0.1% trifluoroacetic acid, 0.2% formic acid, and 0.002% zwittergent 3-16, loaded onto an Halo EXP 2.7 μm C18 trap column (100 mm × 2 cm, Fisher Healthcare) at a flow rate of 8 μl/min and separated on a PepSep RSCL C18 column (1.5 μm, 100 μm × 40 cm, Bruker) heated at 50°C using a 150 min gradient by an Ultimate 3000 system (Thermo Fisher Scientific) coupled with a high-resolution Fourier transform Orbitrap Exploris 480 mass spectrometer (Thermo Scientific). .. Liquid chromatography tandem mass spectometry (LC-MS/MS) Each fraction of peptides was analyzed by LC-MS/MS on a high-resolution Orbitrap Exploris 480 mass spectrometer (Thermo Fisher Scientific).

    Synthesized:

    Article Title: Synthesis and evaluation of nanohybrid pour point depressants as flow improvers for waxy crude oils.
    Article Snippet: .. FTIR (Bruker RX-IFTIR, scanning range 400-4000 cm-1) was used to determine the chemical structure of synthesized polymers. .. Moreover, Bruker Avance Neo, Frequency: 500 MHz, was used to validate the existence of all monomers in the synthesized products.

    Software:

    Article Title: Effect of ultrasonic power settings on intracanal biofilm reduction
    Article Snippet: The acquired images were reconstructed with NRecon v.1.6.6.0 software (Bruker-microCT, Kontich, Belgium). .. The root canal volume (mm 3 ) and surface area (mm 2 ) were determined using CTAn v.1.18.8.0 software (Bruker-microCT, Kontich, Belgium). ..

    Article Title: Effect of ultrasonic power settings on intracanal biofilm reduction.
    Article Snippet: The acquired images were reconstructed with NRecon v.1.6.6.0 software (Bruker-microCT, Kontich, Belgium). .. The root canal volume (mm3) and surface area (mm2) were determined using CTAn v.1.18.8.0 software (Bruker-microCT, Kontich, Belgium). ..



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    Fig. 5. SHT regulates genes expression in renal outer CTX. (A) The experimental design of spatial multi-omics. (B) UMAP dimensionality reduction of spatially resolved transcriptomic spots to visualize clusters. The x-axis and y-axis stand for PC1 and PC2 of UMAP dimensionality reduction in the above figure. Every point in the panel symbolizes a spot. Different colored spots represent different groups. Following the color of the above figure, the below panel depicts the precise spatial distribution of various clusters in the tissue slice of each sample. (C) The heatmap showing the relative intensities of differential gene expression in the outer CTX, inner CTX, outer MDLA, and inner MDLA across the three experimental groups. (D) Oat of tissue map in situ based on 10 <t>×</t> <t>Genomics</t> <t>Visium</t> platform. (E) IHC showing the distribution of Odc1 in renal outer CTX of rats in the three experimental groups. Scale, 50 µm.
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    visium array slide  (10X Genomics)
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    Fig. 5. SHT regulates genes expression in renal outer CTX. (A) The experimental design of spatial multi-omics. (B) UMAP dimensionality reduction of spatially resolved transcriptomic spots to visualize clusters. The x-axis and y-axis stand for PC1 and PC2 of UMAP dimensionality reduction in the above figure. Every point in the panel symbolizes a spot. Different colored spots represent different groups. Following the color of the above figure, the below panel depicts the precise spatial distribution of various clusters in the tissue slice of each sample. (C) The heatmap showing the relative intensities of differential gene expression in the outer CTX, inner CTX, outer MDLA, and inner MDLA across the three experimental groups. (D) Oat of tissue map in situ based on 10 <t>×</t> <t>Genomics</t> <t>Visium</t> platform. (E) IHC showing the distribution of Odc1 in renal outer CTX of rats in the three experimental groups. Scale, 50 µm.
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    Fig. 5. SHT regulates genes expression in renal outer CTX. (A) The experimental design of spatial multi-omics. (B) UMAP dimensionality reduction of spatially resolved transcriptomic spots to visualize clusters. The x-axis and y-axis stand for PC1 and PC2 of UMAP dimensionality reduction in the above figure. Every point in the panel symbolizes a spot. Different colored spots represent different groups. Following the color of the above figure, the below panel depicts the precise spatial distribution of various clusters in the tissue slice of each sample. (C) The heatmap showing the relative intensities of differential gene expression in the outer CTX, inner CTX, outer MDLA, and inner MDLA across the three experimental groups. (D) Oat of tissue map in situ based on 10 × Genomics Visium platform. (E) IHC showing the distribution of Odc1 in renal outer CTX of rats in the three experimental groups. Scale, 50 µm.

    Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

    Article Title: Spatially resolved multi-omics reveals the renal cortex-metabolic reprogramming of Shenhua Tablet for intervention on IgA nephropathy.

    doi: 10.1016/j.phymed.2025.156742

    Figure Lengend Snippet: Fig. 5. SHT regulates genes expression in renal outer CTX. (A) The experimental design of spatial multi-omics. (B) UMAP dimensionality reduction of spatially resolved transcriptomic spots to visualize clusters. The x-axis and y-axis stand for PC1 and PC2 of UMAP dimensionality reduction in the above figure. Every point in the panel symbolizes a spot. Different colored spots represent different groups. Following the color of the above figure, the below panel depicts the precise spatial distribution of various clusters in the tissue slice of each sample. (C) The heatmap showing the relative intensities of differential gene expression in the outer CTX, inner CTX, outer MDLA, and inner MDLA across the three experimental groups. (D) Oat of tissue map in situ based on 10 × Genomics Visium platform. (E) IHC showing the distribution of Odc1 in renal outer CTX of rats in the three experimental groups. Scale, 50 µm.

    Article Snippet: Two adjacent slices were placed on the SUPERFROST PLUS slides (Thermo Fisher, the USA) and 10 × Genomics Visium array slides (https://www.10xgenomics.co m/) for spatial metabolomics and transcriptomics analyses, respectively.

    Techniques: Expressing, Biomarker Discovery, Gene Expression, In Situ

    Fig. 6. SHT regulates the transcriptional heterogeneity of glomeruli and renal tubules in the outer CTX. (A) UMAP and in situ image showing the spatial distribution of diseased and normal glomeruli and renal tubules in the renal outer CTX of rats in the three group samples. (B) Spatial images and expression levels of G6pc1, Pck1, and Gpx3 in glomeruli based on 10x Genomics Visium platform. (C) The correlation analysis showing the negative correlation between G6pc1 and ascorbic acid, whereas the positive correlation between Gpx3 and NAD in renal tubules. The graph below displaying the spatial distribution of ascorbic acid and NAD. (D) Spatial images and expression levels of Gclc, Gpx3, and Oat in glomeruli based on 10x Genomics Visium platform.

    Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

    Article Title: Spatially resolved multi-omics reveals the renal cortex-metabolic reprogramming of Shenhua Tablet for intervention on IgA nephropathy.

    doi: 10.1016/j.phymed.2025.156742

    Figure Lengend Snippet: Fig. 6. SHT regulates the transcriptional heterogeneity of glomeruli and renal tubules in the outer CTX. (A) UMAP and in situ image showing the spatial distribution of diseased and normal glomeruli and renal tubules in the renal outer CTX of rats in the three group samples. (B) Spatial images and expression levels of G6pc1, Pck1, and Gpx3 in glomeruli based on 10x Genomics Visium platform. (C) The correlation analysis showing the negative correlation between G6pc1 and ascorbic acid, whereas the positive correlation between Gpx3 and NAD in renal tubules. The graph below displaying the spatial distribution of ascorbic acid and NAD. (D) Spatial images and expression levels of Gclc, Gpx3, and Oat in glomeruli based on 10x Genomics Visium platform.

    Article Snippet: Two adjacent slices were placed on the SUPERFROST PLUS slides (Thermo Fisher, the USA) and 10 × Genomics Visium array slides (https://www.10xgenomics.co m/) for spatial metabolomics and transcriptomics analyses, respectively.

    Techniques: In Situ, Expressing