trap-eze detection kit (oncor inc) (Oncor Inc)
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Oncor Inc
trap-eze detection kit (oncor inc)
Trap Eze Detection Kit (Oncor Inc), supplied by Oncor Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/trap-eze+oncor/trap+eze+kit/pm10568809-43-22-25
Average 90 stars, based on 1 article reviews
Trap Eze Detection Kit (Oncor Inc), supplied by Oncor Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/trap-eze+oncor/trap+eze+kit/pm10568809-43-22-25
Average 90 stars, based on 1 article reviews
trap-eze detection kit (oncor inc) - by Bioz Stars,
2026-10
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Activity Assay:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. Amplification:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. Polymerase Chain Reaction:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. TRAP Assay:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. Fluorescence:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. Lysis:Article Title: Catecholic flavonoids acting as telomerase inhibitors. Article Snippet: In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents.. Focused screening of several polyhydroxylated flavonoids has allowed us to identify 7,8,3′,4′tetrahydroxyflavone 1 as a new telomerase inhibitor with an interesting in vitro activity in a Flash-Plate assay (IC50 ) 0.2 μM) that has been confirmed in the classical TRAP assay.. Starting from this compound, we developed a medicinal chemistry program to optimize our lead, and in particular to replace one of the two catechols with potential bioisosteres. Article Title: Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid. Article Snippet: Parathyroid cancer is rare, with an estimated incidence of 0.5%–4% in primary hyperparathyroidism.1 This malignant disease is typically characterized by an extraordinarily high serum calcium level, a palpable cervical mass, and invasive tumor growth.. These features are conventionally regarded as the clinical triad to indicate parathyroid cancer.. Parathyroid cancer can be diagnosed pathologically when there is a palisade arrangement and a thick band of connective tissue, invasion of the capsule and vasculature, and a high incidence of mitoses. Article Title: Telomerase activity and human telomerase RNA component in gastrointestinal diseases. Article Snippet: Telomerase activity and human telomerase RNA component in gastrointestinal diseases Article on page 418 Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues Tominaga T, Kashimura H, Suzuki K, et al. strate that telomerase can be a very specific diagnostic and prognostic marker of gastrointestinal cancer; indeed, it is the most specific such marker known to date.7 Previous studies8,9 employing the qualitative TRAP method have, however, not demonstrated the usefulness of telomerase activity as a diagnostic or tumorspecific marker in esophageal cancer, because the activity was detected at a high frequency in the normal esophageal epithelium.. With the introduction of the TRAP-eze kit (Oncor, USA), quantitating the level of telomerase activity in tissue extracts has become easier and more accurate.10 This new quantitative assay system has demonstrated that some progenitor cells and stem cells in gastrointestinal tissues express weak telomerase activity,11,12 and the system has, at the same time, provided new information on a correlation between the telomerase activity and tumor grade and stage, prognostic factors, and patient survival in several cancers.. We have previously shown that the level of telomerase activity increases together with histopathological dedifferentiation and is associated with the clinical outcome in hepatocellular carcinoma.13 In colorectal cancer, a correlation has been shown between the level of telomerase activity and the clinical stage.14 Using a quantitative fluorescence TRAP assay, Tominaga et al.,15 have, as they report in this issue of the Journal of Gastroenterology, demonstrated the level of telomerase activity in various esophageal tissue specimens obtained at endoscopic biopsies. Article Title: Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases Article Snippet: For telomerase activity assay, Article Title: Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo Article Snippet: Article Title: Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Article Snippet: The aim of this study was to evaluate the usefulness of determination of telomerase activity and expression of human telomerase RNA component (hTERC) and human telomerase reverse transcriptase (hTERT) for the diagnosis of lung carcinomas.. The tissues studied consisted of 115 carcinomas and adjacent nonneoplastic lung, which were removed surgically without previous chemotherapy or radiotherapy.. Telomerase activity was determined using a semiquantitative polymerase chain reaction-based telomeric repeat amplification protocol (TRAP) assay. Article Title: Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Article Snippet: Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo.. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders.. However, because of their low frequency in vivo, to obtain a sufficient number of cells for tissue engineering a step of extensive in vitro expansion is required, which could significantly alter BMSC properties. |