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transcriptome analysis  (BioSpyder Technologies)

 
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    BioSpyder Technologies transcriptome analysis
    Hepatocyte maturation status of four different HepG2 models. (A) Bright field pictures showing morphological differences between the different models; HepG2 cultured in 2D and normal DMEM medium, HepG2 cultured in 2D and AAGLY medium, HepG2 cultured in 3D and normal DMEM medium, HepG2 cultured in 3D and AAGLY medium from left to right. (B) <t>Gene</t> <t>expression</t> <t>profiles</t> of some hepatocyte markers ( SERPINA1 and ALB ), CYP enzymes ( 3A4 , 3A7 and 1B1 ) and transporters ( UGT1A1 and SLC10A1 ) and the housekeeping genes ( GAPDH ). Gene expression values are relative to model 1 (HepG2 cultured in 2D and normal DMEM medium) and benchmarked to a pool of 10 different donors of cryopreserved PHHs (10×). N = 6; error bars represent SD; significance levels represented as * P adj < 0.05, ** P adj < 0.01 and *** P adj < 0.001.
    Transcriptome Analysis, supplied by BioSpyder Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/transcriptome+analysis/pmc09071099-125-15-18?v=BioSpyder+Technologies
    Average 90 stars, based on 1 article reviews
    transcriptome analysis - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters"

    Article Title: Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters

    Journal: Mutagenesis

    doi: 10.1093/mutage/geab031

    Hepatocyte maturation status of four different HepG2 models. (A) Bright field pictures showing morphological differences between the different models; HepG2 cultured in 2D and normal DMEM medium, HepG2 cultured in 2D and AAGLY medium, HepG2 cultured in 3D and normal DMEM medium, HepG2 cultured in 3D and AAGLY medium from left to right. (B) Gene expression profiles of some hepatocyte markers ( SERPINA1 and ALB ), CYP enzymes ( 3A4 , 3A7 and 1B1 ) and transporters ( UGT1A1 and SLC10A1 ) and the housekeeping genes ( GAPDH ). Gene expression values are relative to model 1 (HepG2 cultured in 2D and normal DMEM medium) and benchmarked to a pool of 10 different donors of cryopreserved PHHs (10×). N = 6; error bars represent SD; significance levels represented as * P adj < 0.05, ** P adj < 0.01 and *** P adj < 0.001.
    Figure Legend Snippet: Hepatocyte maturation status of four different HepG2 models. (A) Bright field pictures showing morphological differences between the different models; HepG2 cultured in 2D and normal DMEM medium, HepG2 cultured in 2D and AAGLY medium, HepG2 cultured in 3D and normal DMEM medium, HepG2 cultured in 3D and AAGLY medium from left to right. (B) Gene expression profiles of some hepatocyte markers ( SERPINA1 and ALB ), CYP enzymes ( 3A4 , 3A7 and 1B1 ) and transporters ( UGT1A1 and SLC10A1 ) and the housekeeping genes ( GAPDH ). Gene expression values are relative to model 1 (HepG2 cultured in 2D and normal DMEM medium) and benchmarked to a pool of 10 different donors of cryopreserved PHHs (10×). N = 6; error bars represent SD; significance levels represented as * P adj < 0.05, ** P adj < 0.01 and *** P adj < 0.001.

    Techniques Used: Cell Culture, Gene Expression



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    Effects of Different HLP Concentrations on the Relative Expression Levels of DEGs. (A) qPCR Validation of Transcriptomic Results for Peripheral Blood Lymphocytes. (B) qPCR Validation of Transcriptomic Results for Duodenal Tissues. Statistical tests were used for comparisons between groups, where “ns” indicates no significant difference, “**” indicates P < 0.01, and “****” indicates P < 0.0001. Error bars represent the range of mean variation (e.g., standard deviation).

    Journal: Poultry Science

    Article Title: Analysis of the immunomodulatory effects of Honeysuckle leaf polysaccharides on cherry valley ducks based on transcriptomic techniques

    doi: 10.1016/j.psj.2026.106737

    Figure Lengend Snippet: Effects of Different HLP Concentrations on the Relative Expression Levels of DEGs. (A) qPCR Validation of Transcriptomic Results for Peripheral Blood Lymphocytes. (B) qPCR Validation of Transcriptomic Results for Duodenal Tissues. Statistical tests were used for comparisons between groups, where “ns” indicates no significant difference, “**” indicates P < 0.01, and “****” indicates P < 0.0001. Error bars represent the range of mean variation (e.g., standard deviation).

    Article Snippet: Simultaneously, the liver, spleen, and duodenum were collected, rapidly frozen in liquid nitrogen, stored at −80°C, and subsequently sent to Novogene Bio-Technology Co., Ltd. for transcriptomic analysis ( ).

    Techniques: Expressing, Biomarker Discovery, Standard Deviation