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dna microarray method  (CapitalBio Corporation)

 
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    CapitalBio Corporation dna microarray method
    The layout of the <t>DNA</t> <t>microarray</t> method module; each detection panel includes 4 detection modules, which can detect two specimens at the same time. Modules 1 and 3 are used to detect mutations in the rpoB gene, and modules 2 and 4 are used to detect mutations in the katG gene and inhA promoter. QC quality control probe; EC external control probe; BC blank control; NC negative control probe; IC internal control probe; WT wild-type.
    Dna Microarray Method, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tm+dna+microarray+method/pmc08429459-159-21-21?v=CapitalBio+Corporation
    Average 90 stars, based on 1 article reviews
    dna microarray method - by Bioz Stars, 2026-07
    90/100 stars

    Images

    1) Product Images from "Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study"

    Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study

    Journal: Scientific Reports

    doi: 10.1038/s41598-021-97559-y

    The layout of the DNA microarray method module; each detection panel includes 4 detection modules, which can detect two specimens at the same time. Modules 1 and 3 are used to detect mutations in the rpoB gene, and modules 2 and 4 are used to detect mutations in the katG gene and inhA promoter. QC quality control probe; EC external control probe; BC blank control; NC negative control probe; IC internal control probe; WT wild-type.
    Figure Legend Snippet: The layout of the DNA microarray method module; each detection panel includes 4 detection modules, which can detect two specimens at the same time. Modules 1 and 3 are used to detect mutations in the rpoB gene, and modules 2 and 4 are used to detect mutations in the katG gene and inhA promoter. QC quality control probe; EC external control probe; BC blank control; NC negative control probe; IC internal control probe; WT wild-type.

    Techniques Used: Microarray, Control, Negative Control

    The drug susceptibility test was used as a standard method to evaluate the efficacy of the DNA microarray for detecting RIF and INH resistance and MDR-TB.
    Figure Legend Snippet: The drug susceptibility test was used as a standard method to evaluate the efficacy of the DNA microarray for detecting RIF and INH resistance and MDR-TB.

    Techniques Used: Microarray

    Comparison of the diagnostic efficacy of the DNA microarray method when sputum smear grades were ≤ 1 + and ≥ 2 +
    Figure Legend Snippet: Comparison of the diagnostic efficacy of the DNA microarray method when sputum smear grades were ≤ 1 + and ≥ 2 +

    Techniques Used: Comparison, Diagnostic Assay, Microarray

    Specimen processing procedure: A total of 5,911 sputum smear-positive specimens were collected. After experimental processing, 4148 specimens that were positive with the DNA microarray method and DST were finally included in the study. NTM, nontuberculous mycobacteria ; DST, drug sensitivity test.
    Figure Legend Snippet: Specimen processing procedure: A total of 5,911 sputum smear-positive specimens were collected. After experimental processing, 4148 specimens that were positive with the DNA microarray method and DST were finally included in the study. NTM, nontuberculous mycobacteria ; DST, drug sensitivity test.

    Techniques Used: Microarray

    Pattern diagrams of several common drug-resistant gene mutations detected by the DNA microarray method. The white box is the detection site of the wild-type codon, and the red box is the site of the detected mutant codon. ( a ) rpoB gene Leu511Pro (CTG → CCG); ( b ) rpoB gene Asp516Tyr (GAC → TAC); ( c ) rpoB gene His526Tyr (CAC → TAC); ( d ) rpoB gene Ser531Trp (TCG → TGG); ( e ) rpoB gene Ser531Leu (TCG → TTG); ( f ) katG gene Ser315Thr (AGC → ACC); ( g ) katG gene Ser315Asn (AGC → AAC); ( h ) inhA gene promoter-15 (C → T).
    Figure Legend Snippet: Pattern diagrams of several common drug-resistant gene mutations detected by the DNA microarray method. The white box is the detection site of the wild-type codon, and the red box is the site of the detected mutant codon. ( a ) rpoB gene Leu511Pro (CTG → CCG); ( b ) rpoB gene Asp516Tyr (GAC → TAC); ( c ) rpoB gene His526Tyr (CAC → TAC); ( d ) rpoB gene Ser531Trp (TCG → TGG); ( e ) rpoB gene Ser531Leu (TCG → TTG); ( f ) katG gene Ser315Thr (AGC → ACC); ( g ) katG gene Ser315Asn (AGC → AAC); ( h ) inhA gene promoter-15 (C → T).

    Techniques Used: Microarray, Mutagenesis



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    tm dna microarray method  (CapitalBio Corporation)
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    CapitalBio Corporation tm dna microarray method
    CapitalBio™ <t>DNA</t> <t>microarray</t> detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified
    Tm Dna Microarray Method, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tm+dna+microarray+method/pmc05964880-93-3-3?v=CapitalBio+Corporation
    Average 90 stars, based on 1 article reviews
    tm dna microarray method - by Bioz Stars, 2026-07
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    Image Search Results


    CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray, Hybridization, Control, Quantitation Assay, Negative Control, Mutagenesis

    Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray, Mutagenesis

    Performance evaluation of the CapitalBio™ DNA microarray for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray

    Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray

    Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray, Mutagenesis

    Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

    Journal: BMC Infectious Diseases

    Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

    doi: 10.1186/s12879-018-3131-8

    Figure Lengend Snippet: Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

    Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

    Techniques: Microarray, Mutagenesis