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CapitalBio Corporation dna microarray capitalbio (tm)
Dna Microarray Capitalbio (Tm), supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tm)+dna+microarray/capitalbio++dna+microarray/pm29420022-311-20-18
Average 90 stars, based on 1 article reviews
dna microarray capitalbio (tm) - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: .. The CapitalBio™ DNA microarray is a feasible and accurate tool for the species identification of M. tuberculosis and for directly detecting RMP and INH resistance from spinal tuberculosis specimens in fewer than 9 hours. ..

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: .. Overall, the CapitalBio™ DNA microarray is a simple and accurate tool for M. tuberculosis identification and for the diagnosis of RMP and INH resistance, demonstrating that the system is likely to be applicable to spinal tuberculosis specimens. ..

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: .. Clinical specimens (e.g., pus, caseous or granulation tissue) were collected during surgery and were divided into two aliquots for tuberculosis detection; one of the aliquots was subjected to species identification and detection of gene mutations by the CapitalBioTM DNA microarray (CapitalBio Corp., Beijing, China), and the other aliquot was processed for culture and DST. ..

Article Title: Current approaches and developments in transcript profiling of the human placenta
Article Snippet: 2019 , NCBI GEO GSE102897 , Agilent-078298 human ceRNA array V1.0 4X180K , Microarray , Tissue , Chorionic villi , 12 (pooled in pairs) −6 C −6 PE , 3rd trimester , PE vs controls , Hu et al. (2018a ) . .. , Not publically available, but available on request , CapitalBio Genomewide Microarray , Microarray , Tissue , Chorionic villi , 10 (pooled) −5 C −5 PE , 3rd trimester , PE vs controls , Zhou et al. (2006) . .. , Not publically available , Affymetrix Human Genome U133 Plus 2 , Microarray , Tissue , Placenta biopsy (no details provided) , 5 −3 C −2 PE + IUGR , 3rd trimester , PE with IUGR vs controls , Jarvenpaa et al. (2007) .

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: .. Specimens collected during surgery from the tuberculosis patients were subjected to M. tuberculosis species identification and drug-resistance detection by the CapitalBio™ DNA microarray, and results were compared with those obtained from the absolute concentration drug susceptibility testing. .. The CapitalBio™ DNA microarray achieved 93.55% sensitivity for the correct M. tuberculosis species identification of the 93 specimens that tested positive for spinal tuberculosis through culture.

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: Recently, a multitude of commercial molecular DST kits, such as INNO-LiPA, Genotype MDR-TBplus, CapitalBio™ DNA microarray and Xpert MTB/RIF, have been developed for the detection of mutations associated with resistance to RMP and INH [ - ]. .. Among them, the CapitalBioTM DNA microarray that incorporate specific nucleotides at a given position of the rpoB , inhA and katG gene has been developed by CapitalBio Corporation to detect tuberculosis and its multi-drug resistant form in M. tuberculosis isolates and sputum specimens with notable sensitivity and specificity [ , , ]. ..

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: Specimens collected during surgery from the tuberculosis patients were subjected to M. tuberculosis species identification and drug-resistance detection by the CapitalBio™ DNA microarray, and results were compared with those obtained from the absolute concentration drug susceptibility testing. .. The CapitalBio™ DNA microarray achieved 93.55% sensitivity for the correct M. tuberculosis species identification of the 93 specimens that tested positive for spinal tuberculosis through culture. ..

Article Title: Exploring diagnostic methods for drug-resistant tuberculosis: A comprehensive overview.
Article Snippet: Despite available global efforts and funding, Tuberculosis (TB) continues to affect a considerable number of patients worldwide.. Policy makers and stakeholders set clear goals to reduce TB incidence and mortality, but the emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) complicate the reach of these goals.. Drug-resistance TB needs to be diagnosed rapidly and accurately to effectively treat patients, prevent the transmission of MDR-TB, minimise mortality, reduce treatment costs and avoid unnecessary hospitalisations.

Concentration Assay:

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study
Article Snippet: .. Specimens collected during surgery from the tuberculosis patients were subjected to M. tuberculosis species identification and drug-resistance detection by the CapitalBio™ DNA microarray, and results were compared with those obtained from the absolute concentration drug susceptibility testing. .. The CapitalBio™ DNA microarray achieved 93.55% sensitivity for the correct M. tuberculosis species identification of the 93 specimens that tested positive for spinal tuberculosis through culture.



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CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray, Hybridization, Control, Quantitation Assay, Negative Control, Mutagenesis

Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray, Mutagenesis

Performance evaluation of the  CapitalBio™ DNA microarray  for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray

Performance evaluation of the  CapitalBio™ DNA microarray  for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray

 Microarray  chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray, Mutagenesis

 Microarray  chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

Journal: BMC Infectious Diseases

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

doi: 10.1186/s12879-018-3131-8

Figure Lengend Snippet: Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Techniques: Microarray, Mutagenesis