primary rabbit polyclonal anti fut8 antibody (Atlas Antibodies)
Structured Review

Primary Rabbit Polyclonal Anti Fut8 Antibody, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 91/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tissue+microarray+based+immunohistochemistry+analysis/pmc06033451-99-0-10?v=Atlas+Antibodies
Average 91 stars, based on 3 article reviews
Images
1) Product Images from "Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer"
Article Title: Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer
Journal: PLoS ONE
doi: 10.1371/journal.pone.0200315
Figure Legend Snippet: (A) FUT8 mRNA expression was significantly upregulated in primary tumors compared to normal colon mucosa. (B) In five independent datasets of colorectal cancer, higher levels of FUT8 mRNA expression were consistently observed in tumors with wild-type p53 than those of mutant p53.
Techniques Used: Expressing, Mutagenesis
Figure Legend Snippet: (A) FUT8 protein expression in colon carcinoma [T] and adjacent colon mucosa [N]. (B) FUT8 was not expressed by non-neoplastic colon mucosal cells. (C) FUT8 staining was typically found in cytoplasm of tumor cells. (D) Occasionally, concomitant cytoplasmic and membranous staining of FUT8 in tumor cells can be found. (E) p53-positive tumor showing strong nuclear staining in cancer cells. (F) p53-negative tumor showing no nuclear staining. Magnification: (A,E,F) x100; (B,C,D) x400.
Techniques Used: Expressing, Staining
Figure Legend Snippet: Clinicopathological characteristics of colorectal cancer patients according to FUT8 expression.
Techniques Used: Expressing, Immunohistochemistry
Figure Legend Snippet: (A,B) FUT8 protein or mRNA expression had no significant impact on survival in both cohorts. (C) In patients with p53-negative tumors, FUT8 protein expression was significantly associated with better survival in the IHC cohort. (D) In patients with wild-type p53 tumors, FUT8 mRNA expression tended to be associated with better survival in the microarray cohort. (E,F) In patients with p53-positive tumors or mutant p53 tumors, FUT8 protein or mRNA expression showed no association with survival.
Techniques Used: Expressing, Microarray, Mutagenesis
Figure Legend Snippet: Univariate and multivariate Cox regression analysis for disease-free survival in patients with stage II and III colorectal cancer.
Techniques Used: Immunohistochemistry, Microarray
Figure Legend Snippet: Univariate and multivariate Cox regression analysis for disease-free survival in patients with stage II and III colorectal cancer according to FUT8 expression and the p53 status.
Techniques Used: Expressing, Immunohistochemistry, Microarray, Mutagenesis
