stereo discovery v12 microscope (Carl Zeiss)
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Structured Review
Carl Zeiss
stereo discovery v12 microscope
Stereo Discovery V12 Microscope, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 96/100, based on 645 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stereo+microscope/SteREO+Discovery%2EV12+microscope+body/pmc09523645-55-6-5
Average 96 stars, based on 645 article reviews
Stereo Discovery V12 Microscope, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 96/100, based on 645 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stereo+microscope/SteREO+Discovery%2EV12+microscope+body/pmc09523645-55-6-5
Average 96 stars, based on 645 article reviews
stereo discovery v12 microscope - by Bioz Stars,
2026-11
96/100 stars
Images
1) Product Images from "SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis"
Article Title: SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Journal: Communications Biology
doi: 10.1038/s42003-022-03986-6
Figure Legend Snippet: a Schematic representation of the genetic screen to identify individual SARS-CoV-2 genes with cardiac pathology. Fly images taken using a ZEISS SteREO Discovery.V12 microscope. Scale bar = 0.5 mm. b Quantitation of mortality rate prior to eclosion for each individually expressed SARS-CoV-2 gene from the crosses in a . Mortality was calculated as (CyO wing − straight wing)/CyO wing × 100. n = ~200 flies (across 4 vials). c Graph displaying the lifespan for adult flies carrying SARS-CoV-2 Nsp6 , Orf6 , Orf7a or Nsp3 transgene expression. w 1118 is a wild-type control. d The adult heart phenotype induced by 4X Hand -Gal4, cardioblast-specific overexpression (OE) of the UAS- SARS-CoV-2 Nsp6 transgene. Cardiac actin myofibers were visualized by phalloidin staining. Dotted lines delineate the outline of the heart tube. Arrow points to missing cardiac myofibers. w 1118 is a wild-type control. Scale bars (both) = 40 μm. e Quantitation of adult heart cardiac myofibrillar density relative to control. SARS-CoV-2 Nsp6 (4X Hand -Gal4) flies, and w 1118 is a wild-type control. P value = 5.3E−05. n = 6 flies per genotype. f Schematic representation of heart diastolic and systolic diameter, and the heart period by optical coherence tomography (OCT). Scale bars (top two panels) = 20 μm; (bottom) = 30 μm. g Drosophila heartbeat video images from flies induced by 4X Hand - Gal4 cardioblast-specific overexpression (OE) of the UAS- SARS-CoV-2 Nsp6 transgene. w 1118 is a wild-type control. Scale bars (both) = 25 μm. h Quantitation of adult heart diastolic diameter. n = 10 flies per genotype. P value = 8.3E−08. i Quantitation of heart period, i.e., indication of heart rate. n = 10 flies per genotype. P value = 4.0E−08. Statistical significance (*) defined as P < 0.05 (Student’s t test); data shown as mean ± SD.
Techniques Used: Microscopy, Quantitation Assay, Expressing, Over Expression, Staining, Tomography
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