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stat3 inhibitor  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology stat3 inhibitor
    Stat3 Inhibitor, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 19 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stat3/STAT3+Inhibitor+VII/us09897607-449-0-5
    Average 93 stars, based on 19 article reviews
    stat3 inhibitor - by Bioz Stars, 2026-10
    93/100 stars

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    Related Articles

    Blocking Assay:

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. ..

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. siRNA Transfection According to the gene sequence of rat NgR, a small interfering RNA (siRNA) targeting NgR (NgR siRNA, 5′-UUCUCCGAACGUGUCACGUTT-3′ (sense) and 5′-ACGUGACACGUUCGGAGAATT-3′ (antisense)) was designed. ..

    Activation Assay:

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. ..

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. siRNA Transfection According to the gene sequence of rat NgR, a small interfering RNA (siRNA) targeting NgR (NgR siRNA, 5′-UUCUCCGAACGUGUCACGUTT-3′ (sense) and 5′-ACGUGACACGUUCGGAGAATT-3′ (antisense)) was designed. ..

    Transduction:

    Article Title: A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer
    Article Snippet: For certain experimental setups, the breast cancer cell lines (5 × 10 5 cells/mL) were treated with IL-1β (0.4 ng/mL), IL-6 (20 ng/mL), or TNF-α (1.6 ng/mL) (R&D, USA). .. To inhibit the STAT3-mediated signal transduction, the myeloid cells were pre-incubated for 45 min with previously determined non-toxic doses of a small molecule inhibitor, stattic (5 μM for healthy monocytes and THP-1, 2.5 μM for U937) (Santa Cruz, USA). ..

    Concentration Assay:

    Article Title: Dual STAT-3 and IL-6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL-6/IL-6R/STAT-3 axis
    Article Snippet: .. STAT-3 inhibitor Stt was purchased from Santa Cruz Biotechnology, Inc. and used at non-toxic doses below the reported half-maximal inhibitory concentration (<10 μM) ( ). .. Stt was dissolved in DMSO (Sigma-Aldrich; Merck KGaA) to create 50 mM stock solution and stored in aliquots at −80°C until use.

    Transfection:

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. siRNA Transfection According to the gene sequence of rat NgR, a small interfering RNA (siRNA) targeting NgR (NgR siRNA, 5′-UUCUCCGAACGUGUCACGUTT-3′ (sense) and 5′-ACGUGACACGUUCGGAGAATT-3′ (antisense)) was designed. ..

    Sequencing:

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. siRNA Transfection According to the gene sequence of rat NgR, a small interfering RNA (siRNA) targeting NgR (NgR siRNA, 5′-UUCUCCGAACGUGUCACGUTT-3′ (sense) and 5′-ACGUGACACGUUCGGAGAATT-3′ (antisense)) was designed. ..

    Small Interfering RNA:

    Article Title: The Nogo/Nogo Receptor (NgR) Signal Is Involved in Neuroinflammation through the Regulation of Microglial Inflammatory Activation
    Article Snippet: .. To elucidate the signal pathway related to inflammation cytokine production induced by Nogo-P4, microglia were preincubated with the blocking agent NEP1–40 (Nogo-66(1–40) antagonist peptide) (10 μ m ; Sigma-Aldrich), PI-PLC (0.3 units/ml, Sigma-Aldrich), JSH-23, NF-κB activation inhibitor II (10 μ m ; Selleck Chemicals) or S3I-201, and STAT3 inhibitor VII (20 μ m ; Santa Cruz Biotechnology, Inc.) for 30 min before they were transferred into prepared wells. siRNA Transfection According to the gene sequence of rat NgR, a small interfering RNA (siRNA) targeting NgR (NgR siRNA, 5′-UUCUCCGAACGUGUCACGUTT-3′ (sense) and 5′-ACGUGACACGUUCGGAGAATT-3′ (antisense)) was designed. ..



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