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staining intensity  (TissueGnostics)

 
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    TissueGnostics staining intensity
    Staining Intensity, supplied by TissueGnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/staining+intensity/staining+intensity/pmc06715366-75-2-4
    Average 90 stars, based on 1 article reviews
    staining intensity - by Bioz Stars, 2026-10
    90/100 stars

    Images

    Related Articles

    Comparison:

    Article Title: Fbxw7 increases CCL2/7 in CX3CR1 hi macrophages to promote intestinal inflammation
    Article Snippet: .. Comparison of staining intensity (TissueGnostics) among the groups is shown. ..

    Article Title: PCBP1 acts as a regulator of CCL2 expression in macrophages to induce recruitment of monocyte-derived macrophages into the inflamed colon.
    Article Snippet: Intestinal macrophages with functional plasticity play essential roles in gut immune responses by increasing chemokines and cytokines, thereby contributing to the pathogenesis of inflammatory bowel disease (IBD).. Poly(rC)-binding protein 1 (PCBP1), which is widely expressed in immune cells, binds to nucleic acids in mRNA processing, stabilization, translation and transcription.. However, little is known about the influence of PCBP1 on macrophages and its specific mechanism in inflamed intestines.

    Staining:

    Article Title: Fbxw7 increases CCL2/7 in CX3CR1 hi macrophages to promote intestinal inflammation
    Article Snippet: .. Comparison of staining intensity (TissueGnostics) among the groups is shown. ..

    Article Title: PCBP1 acts as a regulator of CCL2 expression in macrophages to induce recruitment of monocyte-derived macrophages into the inflamed colon.
    Article Snippet: Intestinal macrophages with functional plasticity play essential roles in gut immune responses by increasing chemokines and cytokines, thereby contributing to the pathogenesis of inflammatory bowel disease (IBD).. Poly(rC)-binding protein 1 (PCBP1), which is widely expressed in immune cells, binds to nucleic acids in mRNA processing, stabilization, translation and transcription.. However, little is known about the influence of PCBP1 on macrophages and its specific mechanism in inflamed intestines.



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    Image Search Results


    Distribution trend of TOP2A high expression group and low expression group

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Distribution trend of TOP2A high expression group and low expression group

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Expressing

    Survival prognostic model. A K-M curve, the survival rate of TOP2A high standard group was significantly worse than that of low expression group. B The AUC value of the ROC model was greater than 0.7, indicating that the accuracy of the prognostic model was good ( P < 0.05 is considered statistically significant)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Survival prognostic model. A K-M curve, the survival rate of TOP2A high standard group was significantly worse than that of low expression group. B The AUC value of the ROC model was greater than 0.7, indicating that the accuracy of the prognostic model was good ( P < 0.05 is considered statistically significant)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Expressing

    TOP2A-related gene analysis. A Heat map of genes with strong correlation with TOP2A, red represents positive correlation and blue represents negative correlation. B Correlation circle plot of the above genes, red represents positive correlation and green represents negative correlation. C Biological function analysis of the above genes (GO analysis). D , E Biological function analysis of the above genes (KEGG analysis) ( P < 0.05 is considered statistically significant)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: TOP2A-related gene analysis. A Heat map of genes with strong correlation with TOP2A, red represents positive correlation and blue represents negative correlation. B Correlation circle plot of the above genes, red represents positive correlation and green represents negative correlation. C Biological function analysis of the above genes (GO analysis). D , E Biological function analysis of the above genes (KEGG analysis) ( P < 0.05 is considered statistically significant)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques:

    Correlation analysis of TOP2A and immune cells and genes. A Correlation analysis between TOP2A and immune cells, Macrophages M0 and TOP2A expression have a certain correlation. B The correlation between TOP2A and immune genes was analyzed, and the correlation with CD276 was the strongest. C Expression of TOP2A and trend chart of various immune data ( P < 0.05 is considered statistically significant)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Correlation analysis of TOP2A and immune cells and genes. A Correlation analysis between TOP2A and immune cells, Macrophages M0 and TOP2A expression have a certain correlation. B The correlation between TOP2A and immune genes was analyzed, and the correlation with CD276 was the strongest. C Expression of TOP2A and trend chart of various immune data ( P < 0.05 is considered statistically significant)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Expressing

    Representative IHC of TOP2A staining intensity expression and box plot expression of TOP2A staining score in glioma. A TOP2A staining intensity was weakly positive in glioma. (Magnification, x100; EnVision two-step). B TOP2A staining intensity was moderately positive in glioma. (Magnification, x100; EnVision two-step). C TOP2A staining intensity was strongly positive in glioma. (Magnification, x100; EnVision two-step). D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Representative IHC of TOP2A staining intensity expression and box plot expression of TOP2A staining score in glioma. A TOP2A staining intensity was weakly positive in glioma. (Magnification, x100; EnVision two-step). B TOP2A staining intensity was moderately positive in glioma. (Magnification, x100; EnVision two-step). C TOP2A staining intensity was strongly positive in glioma. (Magnification, x100; EnVision two-step). D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Staining, Expressing

    Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.) A A low-grade glioma tissue showing low TOP2A protein expression (magnification, x10 left and x40 right). B A high-grade glioma tissue showing high TOP2A protein expression (magnification, x10 left and x40 right)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.) A A low-grade glioma tissue showing low TOP2A protein expression (magnification, x10 left and x40 right). B A high-grade glioma tissue showing high TOP2A protein expression (magnification, x10 left and x40 right)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Staining, Expressing, Microscopy

    Survival prognostic model in real world clinical samples. A K-M curve, the survival rate of TOP2A high standard group was significantly worse than that of low expression group. B The AUC value of the ROC model was greater than 0.7, indicating that the accuracy of the prognostic model was good ( P < 0.05 is considered statistically significant)

    Journal: Discover Oncology

    Article Title: The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study

    doi: 10.1007/s12672-025-04051-4

    Figure Lengend Snippet: Survival prognostic model in real world clinical samples. A K-M curve, the survival rate of TOP2A high standard group was significantly worse than that of low expression group. B The AUC value of the ROC model was greater than 0.7, indicating that the accuracy of the prognostic model was good ( P < 0.05 is considered statistically significant)

    Article Snippet: D Box plot expression of TOP2A staining score in low-grade glioma and high-grade glioma. ( P < 0.05 is considered statistically significant) Fig. 8 Representative IHC of TOP2A staining intensity expression in glioma (Images were taken by OLYMPUS SC180 microscope.)

    Techniques: Expressing

    (A–D) The OS curve of the core genes between the 2 risk groups; (E) immunohistochemical staining for 3 HLMRGs in the normal oral mucosa tissue and HNC; (F) correlation between HS3ST1, CYP27A1, STC2, and EGLN2 levels and immune cell infiltration based on CIBERSORT. CIBERSORT = Cell-type Identification By Estimating Relative Subsets Of RNA Transcripts, HLMRG = hypoxia- and lactate metabolism-related genes, HNC = head and neck cancer, OS = overall survival.

    Journal: Medicine

    Article Title: Development and experimental verification of a prognosis model for hypoxia- and lactate metabolism-associated genes in HNSCC

    doi: 10.1097/MD.0000000000042665

    Figure Lengend Snippet: (A–D) The OS curve of the core genes between the 2 risk groups; (E) immunohistochemical staining for 3 HLMRGs in the normal oral mucosa tissue and HNC; (F) correlation between HS3ST1, CYP27A1, STC2, and EGLN2 levels and immune cell infiltration based on CIBERSORT. CIBERSORT = Cell-type Identification By Estimating Relative Subsets Of RNA Transcripts, HLMRG = hypoxia- and lactate metabolism-related genes, HNC = head and neck cancer, OS = overall survival.

    Article Snippet: We further evaluated the immunohistochemical images and staining intensity of HLMRGs in HNSCC and normal tissues in the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

    Techniques: Immunohistochemical staining, Staining