stat3 inhibitor sta 21 (Santa Cruz Biotechnology)

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Santa Cruz Biotechnology stat3 inhibitor sta 21
Stat3 Inhibitor Sta 21, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 4502 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sta+21/Stat3/pm39487455-81-3-8
Average 96 stars, based on 4502 article reviews

stat3 inhibitor sta 21 - by Bioz Stars, 2026-10

96/100 stars

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Cell-Signaling:

Article Title: In vivo exposure to lipopolysaccharide inhibits STAT1 signaling
Article Snippet: Immunoreactive bands were visualized using the Odys‐ sey CLx infrared imaging system (LI‐COR Biosciences, Lincoln, NE, USA). .. The following primary antibodies were purchased from Cell Signaling Technology, Dan‐ vers, MA, USA: anti‐GAPDH (14C10) diluted 1:5000, anti‐phospho‐Tyr701‐STAT1 (58D6) 1:1000, anti‐STAT1 (D1K9Y) 1:1000, anti‐phospho‐Tyr705‐STAT3 (D3A7) 1:1000, and anti‐STAT3 (D1B2J) 1:1000, while the mon‐ oclonal anti‐NF‐κB (F‐6) diluted 1:1000 and anti‐IκBα (H‐4) 1:1000 were from Santa Cruz Biotechnology, Dal‐ las, TX, USA. .. Bound immunoreactivity was detected using either anti‐rabbit or anti‐mouse secondary anti‐ bodies conjugated with IRDye (1:10,000; LI‐COR Biosciences).

other:

Article Title: Visceral and subcutaneous adipose stem cells modulate colorectal cancer cell progression: direct and indirect contact distinctly accelerate tumor aggressiveness.
Article Snippet: Quantification of roundness of elongated cells in direct co-culture in relation to cells in monoculture was performed with ImageJ software.

Article Title: FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.
Article Snippet: Primary antibodies used were anti-FAK (proteintech, Cat#66258-1-Ig), anti-SRC (proteintech, Cat#603151-Ig), anti-JNK1 (proteintech, Cat#66210-1-Ig), anti-JNK2 (PTMALO, Cat#PTM-6948), anti-ACSL4 (SANTA CRUZ, Cat#sc365230), anti-SMAD4 (proteintech, Cat#10231-1-AP), anti-SMAD4 (MCE, Cat#HY-P80326), anti-Phospho-FAK-Ser708 (Wanleibio, Cat#WL02764), anti-Phospho-SRC-Tyr530 (Wanleibio, Cat#WL02114), anti-Phospho-JNK-Thr183/Tyr185 (Wanleibio, Cat#WL01813), antiGAPDH (proteintech, Cat#60004-1-Ig).

Control:

Article Title: Exploring the immunomodulatory effects of environmental contaminants on autoimmune patients: An in vitro approach
Article Snippet: Following washes, membranes were incubated with HRP-conjugated secondary antibodies, and signals were detected using PierceTM ECL substrate (Thermo Scientific, Waltham, MA, USA) on a ChemiDocTM MP imaging system (Bio-Rad, Hercules, CA, USA). .. Membranes were stripped and re-probed for total AKT, NFκB p65, p38 MAPK, STAT1, STAT3, and β-actin (Cell Signaling Technology, Danvers, MA, USA; Santa Cruz Biotechnology, Dallas, TX, USA) as a loading control. ..

shRNA:

Article Title: STING–STAT3–SOX18 Axis Drives EndMT and Epigenetic Reprogramming in SAVI Lung Fibrosis
Article Snippet: The following day, cells were transfected with siRNA plasmids using Lipofectamine RNAiMAX transfection reagent (Thermo Fisher Scientific, Cat# 13778075) following the manufacturer’s instructions. .. shRNA (h) lentiviral particles for STAT3 (Catsc-29493-V), STAT1 (Cat#sc-44123-V), STING1 (previously TMEM173) (Cat#sc-92042-V), and scrambled controls (sc-108080) were purchased from Santa Cruz. .. Subsequently, HLMECs were treated with 20 μg/ml of the STING ligand Cyclic [G(2’,5’)pA(3’,5’)p] (2’3’cGAMP) (Invivogen, Cat# tlrl-nacga23-5) and/or 1000 units/ml IFNβ (human IFN beta 1a, PBL Assay Science, Cat# 11410-2).

Incubation:

Article Title: CYBRD1 is transcriptionally regulated by RUNX1 and mediates JAK2/STAT3 signaling activation during ovarian cancer progression.
Article Snippet: The protein concentration was quantified with a BCA protein assay kit (Thermo Fisher Scientific), and 1– 1.5 mg of total protein per sample was used for immunoprecipitation. .. For IP of endogenous protein, the lysates were rotated overnight at 4 °C with anti‐STAT3 or anti‐JAK2 antibodies and then incubated for 3 h with Protein A/G PLUS‐Agarose beads (Santa Cruz) to capture the immunocomplexes. .. For the Flag‐CYBRD1 pulldowns, the lysates were incubated overnight at 4 °C with anti‐Flag M2 magnetic beads (Sigma‐Aldrich).

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