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s ko 03334 morrbid  (Cyagen Biosciences)


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    Cyagen Biosciences s ko 03334 morrbid
    S Ko 03334 Morrbid, supplied by Cyagen Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+st+sequencing/Ncf2/pm40272982-676-93-96
    Average 93 stars, based on 1 article reviews
    s ko 03334 morrbid - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Labeling:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Gene Expression:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Biomarker Discovery:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Lysis:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Ligation:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    DNA Sequencing:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Double Staining:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Nitric Oxide Assay:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    RNA Sequencing:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Spatial Transcriptomics:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Software:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.

    Sequencing:

    Article Title: Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER EasySepTM Mouse Hematopoietic Progenitor Cell Isolation Kit STEMCELL Cat# 19856A Mouse MIF (Macrophage Migration Inhibitory Factor) ELISA Kit Elabscience Cat# E-EL-M0771 Mouse IL-1β ELISA Kit MULTI SCIENCES Cat# EK201B/3-48 Proinflammatory Panel 1 (mouse) kits MSD Cat# K15048D Sodium Dodecyl Sulfate (SDS) GenStar Cat# ZE153-101S Protein Free Rapid Blocking Buffer(5×) EpiZyme Cat# PS108 StarSignal Chemiluminescent Assay Kit Genstar Cat# E171-01 True-NuclearTM Transcription Factor Buffer Set BioLegend Cat# 424401 Reactive Oxygen Species Assay Kit Beyotime Cat# S0033S Tissue-Tek® O.C.T. .. Compound SAKURA Cat# 4583 SeekSpace sc-Spatial Labeling Kit V 1.0 SEEKGENE NA BMKMANU S1000 Gene Expression Kit Biomarker NA QIAzol Lysis Reagent QIAGEN Cat# 79306 Illumina Stranded mRNA Prep, Ligation kit Illumina Cat# 20040534 FastDNATM SPIN Kit for Soil MP Biomedicals Cat# 116560300 NEXTFLEX Rapid DNA-Seq Kit Bioo Scientific Cat# 5144-08 Annexin V-PE/7-AAD double staining apoptosis detection kit KeyGEN Cat# KGA1018 Cell and Tissue Lysis Buffer for Nitric Oxide Assay Beyotime Cat# S3090 Nitric oxide test kit Beyotime Cat# S0021S Experimental models: Organisms C57BL/6J Cyagen Biosciences Cat# C001089 Ncf2+/- C57BL/6J Cyagen Biosciences Cat# S-KO-03334 Morrbid+/- C57BL/6J Cyagen Biosciences Contract No. KOCMAIS211018ZQ7 Il1R1+/- C57BL/6J Cyagen Biosciences Cat# S-KO-02635 Deposited data Bulk RNA-seq This paper GSE270426 scRNA-seq This paper GSE271387 Spatial transcriptomics (SeekSpace) This paper GSE270427 Spatial transcriptomics (BMKMANU S1000 ) This paper GSE271222 Software and algorithms R R Core Team http://www.r-project.org/ RStudio RStudio https://rstudio.com/ ImageJ National Institutes of Health https://imagej.net/ij/ GraphPad Prism v.8.3.0 GraphPad https://www.graphpad.com/ Monocle3 NA https://cole-trapnell-lab.github.io/monocle3/ Seurat v4.2.0 Hao et al.67 https://satijalab.org/seurat/ FlowJo v10.0.7 BD Biosciences https://www.flowjo.com/solutions/flowjo pySCENIC v0.11.2 Van de Sande et al.68 https://github.com/aertslab/pySCENIC bcl2fastq2 v2.2.0 Illumina https://support.illumina.com/sequencing/ sequencing_software/bcl2fastqconversion-software.html SeekSpace Tools v1.0.0 SEEKGENE http://seekspace.seekgene.com/ zh/v1.0.0/index.html BSTMatrix 1.0 Biomarker http://www.biomarker.com.cN/ Archives/28318 (Continued on next page) 18 Cell Reports 44, 115612, May 27, 2025 .. The C57BL/6 WT, Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were purchased from Cyagen Biosciences Inc. Morrbid+/-, Il1R1+/-, and Ncf2+/- mice were bred to generate homozygous individuals through self-crossing.



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    Image Search Results


    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Expressing

    Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Dissection, Expressing, Gene Expression