Review



whole transcriptome sequencing wts  (Spatial Transcriptomics Inc)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 86
      Buy from Supplier

    Structured Review

    Spatial Transcriptomics Inc whole transcriptome sequencing wts
    Cancer‐associated secretory (CAS) cells originated from alveolar type 2 (AT2) cells. (A) Principal component analysis (PCA) plot of alveolar type 1 (AT1), AT2 and CAS cells in the solid component of tumour (S) and ground‐glass component of tumour (GG) regions, with lines representing the inferred trajectories. Each dot represents a single cell and is coloured according to cell type. Lines indicate inferred trajectories, estimated using Slingshot. (B) PCA plots of single‐cell transcriptomes, with cells (dots) coloured by region (GG vs. S) (top) and patient (bottom). (C) Pseudotime analysis depicting the gene expression dynamics of surfactant protein A1 (SFTPA1) (AT2 marker), advanced glycation end‐product specific receptor (AGER) (AT1 marker), secretoglobin family 3A member 2 (SCGB3A2) (CAS marker) and carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) (CAS marker) along the inferred trajectory. The black line and points represent lineage 1 (AT2 to AT1), while the red line and points represent lineage 2 (AT2 to CAS). (D) Violin plots showing the expression levels of carcinoembryonic antigen‐related cell adhesion molecule 5 (CEACAM5), CEACAM6 and serine peptidase inhibitor Kazal type 1 (SPINK1) across different samples in CAS cell types from single‐cell RNA <t>sequencing</t> (scRNA‐seq). (E) Box plots displaying normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across different components (N, GG and S, n = 7, respectively) in whole‐transcriptome sequencing analysis. The Kruskal–Wallis test was performed. (F) Box plots showing the normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across normal (N, n = 23) and cancer (C, n = 34) tissues from a study by Zhang et al. (2020). Wilcox statistical significance is indicated by p ‐values. PSN, part‐solid nodule; SCGB3A1, secretoglobin family 3A member 1.
    Whole Transcriptome Sequencing Wts, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/pmc12360329-5-6-21?v=Spatial+Transcriptomics+Inc
    Average 86 stars, based on 1 article reviews
    whole transcriptome sequencing wts - by Bioz Stars, 2026-08
    86/100 stars

    Images

    1) Product Images from "Novel cancer‐associated secretory cells and IL‐1β + macrophages as key players in early lung adenocarcinoma progression in female never‐smokers"

    Article Title: Novel cancer‐associated secretory cells and IL‐1β + macrophages as key players in early lung adenocarcinoma progression in female never‐smokers

    Journal: Clinical and Translational Medicine

    doi: 10.1002/ctm2.70433

    Cancer‐associated secretory (CAS) cells originated from alveolar type 2 (AT2) cells. (A) Principal component analysis (PCA) plot of alveolar type 1 (AT1), AT2 and CAS cells in the solid component of tumour (S) and ground‐glass component of tumour (GG) regions, with lines representing the inferred trajectories. Each dot represents a single cell and is coloured according to cell type. Lines indicate inferred trajectories, estimated using Slingshot. (B) PCA plots of single‐cell transcriptomes, with cells (dots) coloured by region (GG vs. S) (top) and patient (bottom). (C) Pseudotime analysis depicting the gene expression dynamics of surfactant protein A1 (SFTPA1) (AT2 marker), advanced glycation end‐product specific receptor (AGER) (AT1 marker), secretoglobin family 3A member 2 (SCGB3A2) (CAS marker) and carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) (CAS marker) along the inferred trajectory. The black line and points represent lineage 1 (AT2 to AT1), while the red line and points represent lineage 2 (AT2 to CAS). (D) Violin plots showing the expression levels of carcinoembryonic antigen‐related cell adhesion molecule 5 (CEACAM5), CEACAM6 and serine peptidase inhibitor Kazal type 1 (SPINK1) across different samples in CAS cell types from single‐cell RNA sequencing (scRNA‐seq). (E) Box plots displaying normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across different components (N, GG and S, n = 7, respectively) in whole‐transcriptome sequencing analysis. The Kruskal–Wallis test was performed. (F) Box plots showing the normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across normal (N, n = 23) and cancer (C, n = 34) tissues from a study by Zhang et al. (2020). Wilcox statistical significance is indicated by p ‐values. PSN, part‐solid nodule; SCGB3A1, secretoglobin family 3A member 1.
    Figure Legend Snippet: Cancer‐associated secretory (CAS) cells originated from alveolar type 2 (AT2) cells. (A) Principal component analysis (PCA) plot of alveolar type 1 (AT1), AT2 and CAS cells in the solid component of tumour (S) and ground‐glass component of tumour (GG) regions, with lines representing the inferred trajectories. Each dot represents a single cell and is coloured according to cell type. Lines indicate inferred trajectories, estimated using Slingshot. (B) PCA plots of single‐cell transcriptomes, with cells (dots) coloured by region (GG vs. S) (top) and patient (bottom). (C) Pseudotime analysis depicting the gene expression dynamics of surfactant protein A1 (SFTPA1) (AT2 marker), advanced glycation end‐product specific receptor (AGER) (AT1 marker), secretoglobin family 3A member 2 (SCGB3A2) (CAS marker) and carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) (CAS marker) along the inferred trajectory. The black line and points represent lineage 1 (AT2 to AT1), while the red line and points represent lineage 2 (AT2 to CAS). (D) Violin plots showing the expression levels of carcinoembryonic antigen‐related cell adhesion molecule 5 (CEACAM5), CEACAM6 and serine peptidase inhibitor Kazal type 1 (SPINK1) across different samples in CAS cell types from single‐cell RNA sequencing (scRNA‐seq). (E) Box plots displaying normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across different components (N, GG and S, n = 7, respectively) in whole‐transcriptome sequencing analysis. The Kruskal–Wallis test was performed. (F) Box plots showing the normalised expression levels of SFTPA1, SCGB3A2, CEACAM5, CEACAM6 and SPINK1 across normal (N, n = 23) and cancer (C, n = 34) tissues from a study by Zhang et al. (2020). Wilcox statistical significance is indicated by p ‐values. PSN, part‐solid nodule; SCGB3A1, secretoglobin family 3A member 1.

    Techniques Used: Gene Expression, Marker, Expressing, RNA Sequencing, Sequencing



    Similar Products

    spatial transcriptomics sequencing st seq  (Spatial Transcriptomics Inc)
    86
    Spatial Transcriptomics Inc spatial transcriptomics sequencing st seq
    Spatial Transcriptomics Sequencing St Seq, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/pmc12356410-227-0-0?v=Spatial+Transcriptomics+Inc
    Average 86 stars, based on 1 article reviews
    spatial transcriptomics sequencing st seq - by Bioz Stars, 2026-08
    86/100 stars
    		  Buy from Supplier
    spatial transcriptomics sequencing st-seq  (Spatial Transcriptomics Inc)
    90
    Spatial Transcriptomics Inc spatial transcriptomics sequencing st-seq
    Spatial Transcriptomics Sequencing St Seq, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/pmc12160929-266-0-0?v=Spatial+Transcriptomics+Inc
    Average 90 stars, based on 1 article reviews
    spatial transcriptomics sequencing st-seq - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    spatial transcriptome sequencing (st-seq) dataset  (Mendeley Ltd)
    90
    Mendeley Ltd spatial transcriptome sequencing (st-seq) dataset
    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial <t>transcriptome</t> displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.
    Spatial Transcriptome Sequencing (St Seq) Dataset, supplied by Mendeley Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/pmc11266328-46-1-9?v=Mendeley+Ltd
    Average 90 stars, based on 1 article reviews
    spatial transcriptome sequencing (st-seq) dataset - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    spatial transcriptomics sequencing (st-seq)  (Spatial Transcriptomics Inc)
    90
    Spatial Transcriptomics Inc spatial transcriptomics sequencing (st-seq)
    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial <t>transcriptome</t> displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.
    Spatial Transcriptomics Sequencing (St Seq), supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/pmc10942862-252-4-2?v=Spatial+Transcriptomics+Inc
    Average 90 stars, based on 1 article reviews
    spatial transcriptomics sequencing (st-seq) - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Expressing

    Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Dissection, Expressing, Gene Expression