Review




Structured Review

Spatial Transcriptomics Inc gingival spatial transcriptomics data
Acetylcholine signaling and receptor distribution in the periodontal epithelium. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment of epithelial neurotransmitter signaling-related DEGs. Left: upregulated pathways in PD vs. HC; right: downregulated pathways in TP vs. PD. (B) Expression profiles of acetylcholine receptors across different cell types. Receptors not detected in any cells were excluded. (C) Transcript counts of acetylcholine receptor genes from HOKs RNA-seq data. Five receptors detected in all 12 samples (n = 3 per group), with colored shapes representing groups and black bars indicating the mean. Receptors with low expression (zero counts in some samples) were excluded. (D) Expression of acetylcholine receptors CHRNB1 , CHRNA5 , and CHRNA7 in gingival spatial <t>transcriptomics</t> data.
Gingival Spatial Transcriptomics Data, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pmc12675406-12-13-14?v=Spatial+Transcriptomics+Inc
Average 86 stars, based on 1 article reviews
gingival spatial transcriptomics data - by Bioz Stars, 2026-07
86/100 stars

Images

1) Product Images from "Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis"

Article Title: Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis

Journal: Frontiers in Cell and Developmental Biology

doi: 10.3389/fcell.2025.1701252

Acetylcholine signaling and receptor distribution in the periodontal epithelium. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment of epithelial neurotransmitter signaling-related DEGs. Left: upregulated pathways in PD vs. HC; right: downregulated pathways in TP vs. PD. (B) Expression profiles of acetylcholine receptors across different cell types. Receptors not detected in any cells were excluded. (C) Transcript counts of acetylcholine receptor genes from HOKs RNA-seq data. Five receptors detected in all 12 samples (n = 3 per group), with colored shapes representing groups and black bars indicating the mean. Receptors with low expression (zero counts in some samples) were excluded. (D) Expression of acetylcholine receptors CHRNB1 , CHRNA5 , and CHRNA7 in gingival spatial transcriptomics data.
Figure Legend Snippet: Acetylcholine signaling and receptor distribution in the periodontal epithelium. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment of epithelial neurotransmitter signaling-related DEGs. Left: upregulated pathways in PD vs. HC; right: downregulated pathways in TP vs. PD. (B) Expression profiles of acetylcholine receptors across different cell types. Receptors not detected in any cells were excluded. (C) Transcript counts of acetylcholine receptor genes from HOKs RNA-seq data. Five receptors detected in all 12 samples (n = 3 per group), with colored shapes representing groups and black bars indicating the mean. Receptors with low expression (zero counts in some samples) were excluded. (D) Expression of acetylcholine receptors CHRNB1 , CHRNA5 , and CHRNA7 in gingival spatial transcriptomics data.

Techniques Used: Expressing, RNA Sequencing

Distribution of tight junction genes in the periodontal gingival epithelium and their regulation by acetylcholine. (A) Expressions of OCLN, CLDN1, and CDH1 in spatial transcriptomics data. (B) Differential comparison of OCLN, CLDN1, and CDH1 in the epithelial subpopulation of HC versus PD groups (***, p < 0.001). (C) Heatmap showing the expressions of OCLN, CLDN1, and CDH1 for each cluster in HC and PD gingiva. (D) Quantitative polymerase chain reaction (qPCR) validation in HOKs. Data are presented as the mean ± standard error of the mean (SEM). ***, p < 0.001.
Figure Legend Snippet: Distribution of tight junction genes in the periodontal gingival epithelium and their regulation by acetylcholine. (A) Expressions of OCLN, CLDN1, and CDH1 in spatial transcriptomics data. (B) Differential comparison of OCLN, CLDN1, and CDH1 in the epithelial subpopulation of HC versus PD groups (***, p < 0.001). (C) Heatmap showing the expressions of OCLN, CLDN1, and CDH1 for each cluster in HC and PD gingiva. (D) Quantitative polymerase chain reaction (qPCR) validation in HOKs. Data are presented as the mean ± standard error of the mean (SEM). ***, p < 0.001.

Techniques Used: Comparison, Real-time Polymerase Chain Reaction, Biomarker Discovery



Similar Products

99
Akoya Biosciences analysis b multiome data analysis b spatial transcriptomics b rainbow codex analysis d quantification
Analysis B Multiome Data Analysis B Spatial Transcriptomics B Rainbow Codex Analysis D Quantification, supplied by Akoya Biosciences, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm36270275-266-123-132?v=Akoya+Biosciences
Average 99 stars, based on 1 article reviews
analysis b multiome data analysis b spatial transcriptomics b rainbow codex analysis d quantification - by Bioz Stars, 2026-07
99/100 stars
  Buy from Supplier

86
10X Genomics data analysis spatial transcriptomic experiment
Data Analysis Spatial Transcriptomic Experiment, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm42226209-88-10-38?v=10X+Genomics
Average 86 stars, based on 1 article reviews
data analysis spatial transcriptomic experiment - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier

86
Spatial Transcriptomics Inc lung cancer research immune network technology data analysis clinical application spatial transcriptomics • merfish
Lung Cancer Research Immune Network Technology Data Analysis Clinical Application Spatial Transcriptomics • Merfish, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm41619173-675-24-34?v=Spatial+Transcriptomics+Inc
Average 86 stars, based on 1 article reviews
lung cancer research immune network technology data analysis clinical application spatial transcriptomics • merfish - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier

86
Spatial Transcriptomics Inc spatial transcriptomics data analysis
Spatial Transcriptomics Data Analysis, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm41508250-90-0-0?v=Spatial+Transcriptomics+Inc
Average 86 stars, based on 1 article reviews
spatial transcriptomics data analysis - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier

90
LC Bio Co Ltd spatial transcriptome sequencing data analysis
Spatial Transcriptome Sequencing Data Analysis, supplied by LC Bio Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pmc12211156-44-2-15?v=LC+Bio+Co+Ltd
Average 90 stars, based on 1 article reviews
spatial transcriptome sequencing data analysis - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier

90
Spatial Transcriptomics Inc spatial transcriptomics data analysis spaceranger
Spatial Transcriptomics Data Analysis Spaceranger, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm38834904-291-2-0?v=Spatial+Transcriptomics+Inc
Average 90 stars, based on 1 article reviews
spatial transcriptomics data analysis spaceranger - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier

90
Bruker Corporation spatial transcriptomic data analysis
Spatial Transcriptomic Data Analysis, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/pm38885850-400-4-3?v=Bruker+Corporation
Average 90 stars, based on 1 article reviews
spatial transcriptomic data analysis - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier

Image Search Results