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expression profile and somatic mutations data of human cancer cell lines  (Broad Institute Inc)

 
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    Broad Institute Inc expression profile and somatic mutations data of human cancer cell lines
    Expression Profile And Somatic Mutations Data Of Human Cancer Cell Lines, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/somatic+mutation+profiling/transcriptional+profiling+of+human+cancer+cell+lines/pmc09748486-41-2-17
    Average 90 stars, based on 1 article reviews
    expression profile and somatic mutations data of human cancer cell lines - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Mutagenesis:

    Article Title: Investigating the role of senescence biomarkers in colorectal cancer heterogeneity by bulk and single-cell RNA sequencing
    Article Snippet: .. Based on previous study , the somatic mutation data and expression profile data of human cancer cell lines (CCLs) were downloaded from the Broad Institute Cancer Cell Line Encyclopedia (CCLE) project . .. Then, the sensitivity data for 1448 compounds to 482 CCLs was acquired from the PRISM Repurposing dataset (PRISM; https://depmap.org/portal/prism/ ) and the sensitivity data for 481 compounds to 835 CCLs was acquired from Cancer Therapeutics Response Portal (CTRP; https://portals.broadinstitute.org/ctrp ).

    Article Title: Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
    Article Snippet: CNVs in focal genomic loci were delineated using GISTIC2.0 via GenePattern. .. Screening and validation of potential therapeutic compounds for high CAIPS scores in HCC The human cancer cell line expression profiles and somatic mutation data were acquired from the Cancer Cell Line Encyclopedia project at the Broad Institute (https://portals.broadinstitute.org/ccle/)73. .. Drug sensitivity matrices were curated from Profiling Relative Inhibition Simultaneously in Mixtures (PRISM) (https://depmap.org/portal/prism/) and Cancer Therapeutics Response Portal (CTRP) (https://portals.broadinstitute.org/ctrp).

    Expressing:

    Article Title: Investigating the role of senescence biomarkers in colorectal cancer heterogeneity by bulk and single-cell RNA sequencing
    Article Snippet: .. Based on previous study , the somatic mutation data and expression profile data of human cancer cell lines (CCLs) were downloaded from the Broad Institute Cancer Cell Line Encyclopedia (CCLE) project . .. Then, the sensitivity data for 1448 compounds to 482 CCLs was acquired from the PRISM Repurposing dataset (PRISM; https://depmap.org/portal/prism/ ) and the sensitivity data for 481 compounds to 835 CCLs was acquired from Cancer Therapeutics Response Portal (CTRP; https://portals.broadinstitute.org/ctrp ).

    Article Title: Pyroptosis-related lncRNAs: A novel prognosis signature of colorectal cancer
    Article Snippet: .. After that, expression profile and somatic mutations data of human cancer cell lines were obtained from the Broad Institute Cancer Cell Line Encyclopedia (CCLE) project ( https://portals.broadinstitute.org/ccle/ ) ( ). ..

    Article Title: Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
    Article Snippet: CNVs in focal genomic loci were delineated using GISTIC2.0 via GenePattern. .. Screening and validation of potential therapeutic compounds for high CAIPS scores in HCC The human cancer cell line expression profiles and somatic mutation data were acquired from the Cancer Cell Line Encyclopedia project at the Broad Institute (https://portals.broadinstitute.org/ccle/)73. .. Drug sensitivity matrices were curated from Profiling Relative Inhibition Simultaneously in Mixtures (PRISM) (https://depmap.org/portal/prism/) and Cancer Therapeutics Response Portal (CTRP) (https://portals.broadinstitute.org/ctrp).

    Article Title: USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells
    Article Snippet: .. TCGA PANCAN samples used in this analysis are shown in . (E) Expression of USP15 from transcriptional profiling of human cancer cell lines (CCLE, Broad Institute). (F) USP15 normalized expression levels in a panel of leukemia cell lines as assessed by qRT-PCR and RNA-seq by CCLE. ..

    other:

    Article Title: Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy
    Article Snippet: Transcriptome data of human cancer cell lines (CCLs) were downloaded from the Broad Institute-Cancer Cell Line Encyclopedia project (CCLE, https://sites.broadinstitute.org/ccle/ ) and the CERES scores, the score to evaluate the dependency of the certain gene in the CCL, which indicated that the score was negative correlation with the possible significance of the gene in cell proliferation of the certain CCL, were downloaded from the dependency map portal (DepMap, https://depmap.org/portal/ ).

    Biomarker Discovery:

    Article Title: Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
    Article Snippet: CNVs in focal genomic loci were delineated using GISTIC2.0 via GenePattern. .. Screening and validation of potential therapeutic compounds for high CAIPS scores in HCC The human cancer cell line expression profiles and somatic mutation data were acquired from the Cancer Cell Line Encyclopedia project at the Broad Institute (https://portals.broadinstitute.org/ccle/)73. .. Drug sensitivity matrices were curated from Profiling Relative Inhibition Simultaneously in Mixtures (PRISM) (https://depmap.org/portal/prism/) and Cancer Therapeutics Response Portal (CTRP) (https://portals.broadinstitute.org/ctrp).

    Quantitative RT-PCR:

    Article Title: USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells
    Article Snippet: .. TCGA PANCAN samples used in this analysis are shown in . (E) Expression of USP15 from transcriptional profiling of human cancer cell lines (CCLE, Broad Institute). (F) USP15 normalized expression levels in a panel of leukemia cell lines as assessed by qRT-PCR and RNA-seq by CCLE. ..

    RNA Sequencing:

    Article Title: USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells
    Article Snippet: .. TCGA PANCAN samples used in this analysis are shown in . (E) Expression of USP15 from transcriptional profiling of human cancer cell lines (CCLE, Broad Institute). (F) USP15 normalized expression levels in a panel of leukemia cell lines as assessed by qRT-PCR and RNA-seq by CCLE. ..



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