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sequencing of 74 genes and genotyping of 24 single nucleotide variants (snvs)  (Medical Genetics Laboratories)

 
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    Medical Genetics Laboratories sequencing of 74 genes and genotyping of 24 single nucleotide variants (snvs)
    Sequencing Of 74 Genes And Genotyping Of 24 Single Nucleotide Variants (Snvs), supplied by Medical Genetics Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/snv+sequence/pmc07475159-208-5-16?v=Medical+Genetics+Laboratories
    Average 90 stars, based on 1 article reviews
    sequencing of 74 genes and genotyping of 24 single nucleotide variants (snvs) - by Bioz Stars, 2026-08
    90/100 stars

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    Completed observational ctDNA studies in non-metastatic/oligometastatic CRC.

    Journal: Cancers

    Article Title: ctDNA and Adjuvant Therapy for Colorectal Cancer: Time to Re-Invent Our Treatment Paradigm

    doi: 10.3390/cancers13020346

    Figure Lengend Snippet: Completed observational ctDNA studies in non-metastatic/oligometastatic CRC.

    Article Snippet: Overman et al., 2017 [ ] , 54 , IV (resectable liver metastases) , 30 kb ctDNA digital sequencing panel (Guardant Health) covering SNVs in 21 genes , Not reported , In 43 patients who underwent successful resection of all visible disease, post-op detection of ctDNA significantly correlated with RFS (HR, 3.1; 95% CI, 1.7–9.1; p = 0.002) with 2-year RFS of 0% vs. 47%. ctDNA detected at median of 5.1 months prior to radiographic recurrence. , Post-op: 44% Post-Treatment: Not reported Surveillance: Not reported.

    Techniques: Adjuvant, Methylation, Clinical Proteomics, Sequencing